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Mediastinal Lymphoma

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Target Volume Delineation and Treatment Planning for Particle Therapy

Part of the book series: Practical Guides in Radiation Oncology ((PGRO))

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Abstract

Hodgkin lymphoma and primary mediastinal large B cell lymphoma (a form of non-Hodgkin lymphoma) are lymphomas that commonly involve the mediastinum and typically affect adolescents and young adults. Owing to the young age at presentation and excellent cure rates with combined-modality therapy, late effects from treatment can cause significant problems for survivors decades later. Due to the combination of chemotherapy and radiation, patients are at risk for cardiovascular complications and secondary cancers. Proton therapy is a radiation technology that can be used to help reduce the radiation dose to the organs at risk compared with traditional photon radiation. In patients with mediastinal lymphoma, proton therapy can help reduce the radiation dose to the heart, lungs, breast, esophagus, and total body, which is expected to translate into fewer long-term toxicities from radiation. This chapter is an overview of proton planning for mediastinal lymphoma.

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Authors and Affiliations

  1. Department of Radiation Oncology, University of Florida College of Medicine, 2000 SW Archer Road, Gainesville, FL, 33710, USA

    Bradford S. Hoppe & Stella Flampouri

  2. Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

    Christine Hill-Kayser & John P. Plastaras

Authors
  1. Bradford S. Hoppe
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  2. Stella Flampouri
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  3. Christine Hill-Kayser
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  4. John P. Plastaras
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Corresponding author

Correspondence to Bradford S. Hoppe .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    Nancy Y. Lee

  2. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Jonathan E. Leeman

  3. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Oren Cahlon

  4. Department of Medical Dosimetry, ProCure Proton Therapy Center, Somerset, New Jersey, USA

    Kevin Sine

  5. Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China

    Guoliang Jiang

  6. Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China

    Jiade J. Lu

  7. Department of Radiation Oncology, University Medical Center Groningen, Groningen, The Netherlands

    Stefan Both

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Hoppe, B.S., Flampouri, S., Hill-Kayser, C., Plastaras, J.P. (2018). Mediastinal Lymphoma. In: Lee, N., et al. Target Volume Delineation and Treatment Planning for Particle Therapy. Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-42478-1_23

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  • DOI: https://doi.org/10.1007/978-3-319-42478-1_23

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-42477-4

  • Online ISBN: 978-3-319-42478-1

  • eBook Packages: MedicineMedicine (R0)

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