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Non-melanoma Skin Cancer with Clinical Perineural Invasion

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Target Volume Delineation and Treatment Planning for Particle Therapy

Part of the book series: Practical Guides in Radiation Oncology ((PGRO))

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Abstract

Non-melanoma skin cancer (NMSC) is the most common cancer in the USA and includes cutaneous basal cell and squamous cell carcinoma [1]. Although these skin cancers often present as localized and resectable [2], rarely, NMSC can present or recur with clinical perineural invasion, a condition wherein tumor cells surround nearby nerve sheaths and spread proximally along the motor or sensory nerve to the base of skull [3, 4]. Because highdose radiation therapy may also cause significant morbidity, the superior conformality of particle therapy may improve the therapeutic ratio in the management of NMSCs with clinical perineural invasion when compared to photon-based radiation therapy [5].

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References

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Authors and Affiliations

  1. University of Florida Health Proton Therapy Institute, 2015 North Jefferson St., Jacksonville, FL, 32206, USA

    Curtis Bryant & Roi Dagan

Authors
  1. Curtis Bryant
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  2. Roi Dagan
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Correspondence to Curtis Bryant .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    Nancy Y. Lee

  2. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Jonathan E. Leeman

  3. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Oren Cahlon

  4. Department of Medical Dosimetry, ProCure Proton Therapy Center, Somerset, New Jersey, USA

    Kevin Sine

  5. Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China

    Guoliang Jiang

  6. Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China

    Jiade J. Lu

  7. Department of Radiation Oncology, University Medical Center Groningen, Groningen, The Netherlands

    Stefan Both

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Bryant, C., Dagan, R. (2018). Non-melanoma Skin Cancer with Clinical Perineural Invasion. In: Lee, N., et al. Target Volume Delineation and Treatment Planning for Particle Therapy. Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-42478-1_10

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  • DOI: https://doi.org/10.1007/978-3-319-42478-1_10

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-42477-4

  • Online ISBN: 978-3-319-42478-1

  • eBook Packages: MedicineMedicine (R0)

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