The field of metabolic engineering, loosely defined as the manipulation of living organisms to achieve a desired metabolic objective, has grown and advanced significantly over the past 20 years. First applied to improve organisms producing existing biochemicals, it is now a promising approach to develop biocatalysts for the production of nonnatural fuels and chemicals previously accessible only through petrochemical processes. New tools such as gene synthesis, advanced cloning techniques, ‘omics’ analysis, and mathematical modeling have greatly accelerated the pace of innovation in the field, leading to many success stories and even some commercialization examples. This volume reviews the current state of the art in tools and technologies for metabolic engineering.
KeywordsMetabolic Engineering Success Story Flux Balance Analysis Metabolic Control Analysis Metabolic Engineer
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