Skip to main content

General Description

  • Chapter
  • First Online:
Book cover Management of Soft Tissue Sarcoma

Abstract

Soft tissue sarcomas are an unusual group of tumors deriving their name from the Greek term for a fleshy excrescence. As early as Galen (130–200 C.E.), it was suggested they were a cancerous tumor and caution advised against any surgical intervention [1]. Early reports of myxoid liposarcoma by Severinius (1580–1637) and retroperitoneal liposarcoma by Morgagni (1682–1771) have been recorded [2]. Wardrop (1782–1869), an Edinburgh surgeon who had studied in Vienna, introduced the term soft cancer. In his book Surgical Observations, published in 1816, Charles Bell (1772–1842) has been credited with the utilization of the term soft tissue sarcoma to differentiate it from carcinoma [3]. The first classification of sarcoma has been attributed to Abernethy in 1804. Johannes Müller (1801–1858) has been credited with coining the term desmoid in 1838 [3]. Stout (1885–1967) published a seminal monograph in 1932 on the pathology and treatment of sarcomas [4].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Long ER. History of pathology. Baltimore: Williams & Wilkins; 1928.

    Google Scholar 

  2. Morgagni JB. The seats and causes of disease investigated by anatomy. London: Millen & Cadell; 1769. letter 39

    Google Scholar 

  3. Hajdu SI. Differential diagnosis of soft tissue and bone tumors. Philadelphia: Lea & Febiger; 1986.

    Google Scholar 

  4. Stout AP. Human cancer: etiologic factors, precancerous lesions growth, spread, symptoms, diagnosis, prognosis, principles of treatment. Philadelphia: Lea & Febiger; 1932.

    Google Scholar 

  5. Ewing J. Further report on endothelial myeloma. Proc N Y Pathol Soc. 1924;24:93–101.

    Google Scholar 

  6. Stout AP. Tumors of the soft tissues, atlas of tumor pathology. Washington, DC: Armed Forces Institute of Pathology; 1953.

    Google Scholar 

  7. Stewart FW, Treves N. Lymphangiosarcoma in postmastectomy lymphedema: a report of six cases of elephantiasis chirurgica. Cancer. 1948;1:64–81.

    Article  CAS  PubMed  Google Scholar 

  8. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin. 2016;66:7–30.

    Article  PubMed  Google Scholar 

  9. Nilsson B, Bumming P, Meis-Kindblom JM, et al. Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era—a population-based study in western Sweden. Cancer. 2005;103:821–9.

    Article  PubMed  Google Scholar 

  10. Li FP, Fraumeni Jr JF. Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome? Ann Intern Med. 1969;71:747–52.

    Article  CAS  PubMed  Google Scholar 

  11. D'Agostino AN, Soule EH, Miller RH. Sarcomas of the peripheral nerves and somatic soft tissues associated with multiple neurofibromatosis (Von Recklinghausen’s disease). Cancer. 1963;16:1015–27.

    Article  PubMed  Google Scholar 

  12. Fraumeni Jr JF, Vogel CL, Easton JM. Sarcomas and multiple polyposis in a kindred. A genetic variety of hereditary polyposis? Arch Intern Med. 1968;121:57–61.

    Article  PubMed  Google Scholar 

  13. Sorensen SA, Mulvihill JJ, Nielsen A. Long-term follow-up of von Recklinghausen neurofibromatosis. Survival and malignant neoplasms. N Engl J Med. 1986;314:1010–5.

    Article  CAS  PubMed  Google Scholar 

  14. Abramson DH, Melson MR, Dunkel IJ, et al. Third (fourth and fifth) nonocular tumors in survivors of retinoblastoma. Ophthalmology. 2001;108:1868–76.

    Article  CAS  PubMed  Google Scholar 

  15. Abramson DH, Dunkel IJ, Brodie SE, et al. A phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma initial results. Ophthalmology 2008;115:1398–404.

    Google Scholar 

  16. Brady MS, Gaynor JJ, Brennan MF. Radiation-associated sarcoma of bone and soft tissue. Arch Surg. 1992;127:1379–85.

    Article  CAS  PubMed  Google Scholar 

  17. Kirova YM, Vilcoq JR, Asselain B, et al. Radiation-induced sarcomas after radiotherapy for breast carcinoma: a large-scale single-institution review. Cancer. 2005;104:856–63.

    Article  PubMed  Google Scholar 

  18. Gladdy RA, Qin LX, Moraco N, et al. Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas? J Clin Oncol. 2010;28:2064–9.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Muller R, Hajdu SI, Brennan MF. Lymphangiosarcoma associated with chronic filarial lymphedema. Cancer. 1987;59:179–83.

    Article  CAS  PubMed  Google Scholar 

  20. Burningham Z, Hashibe M, Spector L, et al. The epidemiology of sarcoma. Clin Sarcoma Res. 2012;2:14.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Brennan, M.F., Antonescu, C.R., Alektiar, K.M., Maki, R.G. (2016). General Description. In: Management of Soft Tissue Sarcoma. Springer, Cham. https://doi.org/10.1007/978-3-319-41906-0_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-41906-0_1

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-41904-6

  • Online ISBN: 978-3-319-41906-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics