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Biomedical Applications

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Applications of Chalcogenides: S, Se, and Te

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Abstract

This chapter deals with some of the important biomedical applications of chalcogenide materials in early detection as well as fast cure of some of the critical illnesses. In particular, bio-conjugated nanoparticles of chalcogenides may be used for applications in drug delivery, biosensing, and bioimaging. Toxicity of Se decreases in going from its ionic forms to organic compounds, especially containing zero oxidation state Se (red nano Se). It is known that addition of BSA to the sodium selenite–glutathione redox system results in formation of red amorphous selenium which is seven times less toxic than sodium selenite but retains the profile and level of biological activity of sodium selenite. Selenium has been shown to prevent cancer in numerous animal model systems when fed at levels exceeding the nutritional requirement. Although it is convenient to describe the effects of Se in terms of the element, it must always be kept in mind that chemical form and dose are determinants of its biological activities as an essential nutrient, cancer preservative agent, or toxicant.

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Authors and Affiliations

  1. Department of Natural and Applied Sciences, University of Wisconsin - Green Bay, 2420 Nicolet Drive, Green Bay, WI, 54311–7001, USA

    Mandeep Singh Bakshi Ph.D.

  2. Department of Physics College of The North Atlantic, Materials and Nanotechnology Research Laboratory, Labrador West Campus, 1600 Nichols Adam Highway, Labrador City, A2V 0B8, NL, Canada

    Gurinder Kaur Ahluwalia Ph.D

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  1. Mandeep Singh Bakshi Ph.D.
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Correspondence to Mandeep Singh Bakshi Ph.D. .

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  1. Materials and Nanotechnology Research Laboratory Department of Physics, College of The North Atlantic, Labrador City, Newfoundland and Labrador, Canada

    Gurinder Kaur Ahluwalia

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Bakshi, M.S., Ahluwalia, G.K. (2017). Biomedical Applications. In: Ahluwalia, G. (eds) Applications of Chalcogenides: S, Se, and Te. Springer, Cham. https://doi.org/10.1007/978-3-319-41190-3_7

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