Biomedical Applications



This chapter deals with some of the important biomedical applications of chalcogenide materials in early detection as well as fast cure of some of the critical illnesses. In particular, bio-conjugated nanoparticles of chalcogenides may be used for applications in drug delivery, biosensing, and bioimaging. Toxicity of Se decreases in going from its ionic forms to organic compounds, especially containing zero oxidation state Se (red nano Se). It is known that addition of BSA to the sodium selenite–glutathione redox system results in formation of red amorphous selenium which is seven times less toxic than sodium selenite but retains the profile and level of biological activity of sodium selenite. Selenium has been shown to prevent cancer in numerous animal model systems when fed at levels exceeding the nutritional requirement. Although it is convenient to describe the effects of Se in terms of the element, it must always be kept in mind that chemical form and dose are determinants of its biological activities as an essential nutrient, cancer preservative agent, or toxicant.


Drug delivery Biomedical applications Anticarcinogenic Nano selenium Chalcogenides Selenium metabolism Cancer 


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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Mandeep Singh Bakshi
    • 1
  • Gurinder Kaur Ahluwalia
    • 2
  1. 1.Department of Natural and Applied SciencesUniversity of Wisconsin - Green BayGreen BayUSA
  2. 2.Department of Physics College of The North AtlanticMaterials and Nanotechnology Research LaboratoryLabrador CityCanada

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