Abstract
DNA microarrays were developed in the mid 1990s and are an efficient tool that can take a snapshot of a cells active expressed DNA. By allowing fast and inexpensive analysis, microarrays have exploded in use. They work by fixing a short segment of cDNA or segment of oligonucleotides called a probe, to a silicon or glass backing. The probes are exposed to tissue extracted nucleic acids and if present will bind to the probe causing fluorescence. A single microarray chip the length of a matchstick can fit tens of thousands of probes at relatively low cost providing significant advantage over other techniques.
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Collins, J., Kittipongdaja, P., Morgan, M. (2016). What’s New in Dermatopathology?. In: Norman, R. (eds) Personalized, Evolutionary, and Ecological Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-41088-3_6
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DOI: https://doi.org/10.1007/978-3-319-41088-3_6
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