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Inorganic Polyphosphates in Eukaryotic Cells pp 3–14Cite as

The Role of Inorganic Polyphosphates in Stress Response and Regulation of Enzyme Activities in Yeast

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Abstract

Inorganic polyphosphates (polyPs) are multifunctional compounds involved in adaptation of microorganisms to stress. In yeast, polyPs serve a reserve of phosphorus that is consumed by cells with phosphate deficiency. Under phosphate excess, polyP biosynthesis regulates the intracellular phosphate concentration. PolyPs accumulate under conditions of growth suppression under nitrogen starvation and heavy metal toxic stress, and also upon the adaptation of yeast to a hydrophobic carbon source. The participation of polyPs in the regulation of enzyme activities is discussed.

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Acknowledgments

The research was supported by Russian Foundation for Basic Research (grant 16-04-00396).

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Authors and Affiliations

  1. Laboratory of Regulation of Biochemical Processes, Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia

    Tatiana Kulakovskaya

  2. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia

    Lubov Ryasanova, Vladimir Dmitriev & Anton Zvonarev

Authors
  1. Tatiana Kulakovskaya
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  2. Lubov Ryasanova
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  3. Vladimir Dmitriev
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  4. Anton Zvonarev
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Corresponding author

Correspondence to Tatiana Kulakovskaya .

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Editors and Affiliations

  1. Laboratory of Regulation of Biochemical Processes, Skryabin Institute of Biochemistry and Physiology of Microorganisms Russian Academy of Sciences, Pushchino, Russia

    Tatiana Kulakovskaya

  2. NYU College of Dentistry, New York, New York, USA

    Evgeny Pavlov

  3. Department of Pharmacology, University of California, Davis, California, USA

    Elena N. Dedkova

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Kulakovskaya, T., Ryasanova, L., Dmitriev, V., Zvonarev, A. (2016). The Role of Inorganic Polyphosphates in Stress Response and Regulation of Enzyme Activities in Yeast. In: Kulakovskaya, T., Pavlov, E., Dedkova, E. (eds) Inorganic Polyphosphates in Eukaryotic Cells. Springer, Cham. https://doi.org/10.1007/978-3-319-41073-9_1

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