Abstract
The standard method of diagnosing prostate cancer is TRUS-guided biopsy; although there is general consensus on how this procedure should be conducted to maximize prostate cancer detection rates, concerns remain about false-negative results on the one hand and poor representation of cancer, both in terms of burden of disease and of grade, on the other.
HistoScanningTM (HS) (Advanced Medical Diagnostics, Waterloo, Belgium) is a technology that detects specific changes in the tissue morphology by extracting and quantifying statistical features from backscattered ultrasonography data. The core of HistoScanning consists of a set of ‘tissue characterization algorithms’ that has been developed to distinguish cancerous and noncancerous tissues in solid organs.
Different studies have shown that prostate HistoScanning has the ability to identify and locate prostate cancer and, consequently, may aid in pretreatment and presurgical planning. In men with a lesion identified, it has potential to enable improved targeting, allowing better risk stratification by obtaining more representative cores.
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Maccagnano, C., Scattoni, V. (2017). HistoScanning. In: Martino, P., Galosi, A. (eds) Atlas of Ultrasonography in Urology, Andrology, and Nephrology. Springer, Cham. https://doi.org/10.1007/978-3-319-40782-1_51
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DOI: https://doi.org/10.1007/978-3-319-40782-1_51
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