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Gasotransmitters in Plants pp 201–215Cite as

Protein Denitrosylation in Plant Biology

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Part of the book series: Signaling and Communication in Plants ((SIGCOMM))

Abstract

Nitric oxide (NO) is a key signalling molecule involved in fundamental processes in animals and plants. NO mainly transmits its action through post-translational modifications (NO-PTMs), among which S-nitrosylation, the covalent attachment of an NO group to a rare, highly reactive cysteine (Cys) thiol to form an S-nitrosothiol (SNO), is preeminent. In the last decade, the numbers of proteins identified that undergo S-nitrosylation have significantly increased. This analysis has revealed that a wide range of both physiological and stress response processes are regulated by this post-translational modification. To function effectively as a molecular cue, S-nitrosylation must be specific and reversible. Denitrosylation, the removal of an NO group from an SNO, has emerged as a key regulatory process. While the role of S-nitrosylation in plant biology has garnered significant attention, denitrosylation, a pivotal counterpoint, remains relatively unexplored. In plants, S-nitrosoglutathione reductase (GSNOR) and thioredoxin reductase (Trx)-mediated denitrosylation have emerged as key mechanisms for denitrosylation.

This chapter describes the current state of the art with respect to the role of denitrosylation in plant biology.

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References

  • Achkor H, Díaz M, Fernández MR, Biosca JA, Parés X, Martínez MC (2003) Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis. Plant Physiol 132(4):2248–2255

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Alderton WK, Cooper CH, Knowles R (2001) Nitric oxide synthases: structure, function and inhibition. Biochem J 357:593–615

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Anand P, Stamler JS (2012) Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease. J Mol Med 90(3):233–244

    Article  CAS  PubMed  Google Scholar 

  • Astier J, Rasul S, Koen E, Manzoor H, Besson-Bard A, Lamotte O, Jeandroz S, Durner J, Lindermayr C, Wendehenne D (2011) S-nitrosylation: an emerging post-translational protein modification in plants. Plant Sci 181(5):527–533

    Article  CAS  PubMed  Google Scholar 

  • Begara-Morales JC, Sánchez-Calvo B, Chaki M, Valderrama R, Mata-Pérez C, López-Jaramillo J, Padilla MN, Carreras A, Corpas FJ, Barroso JB (2014a) Dual regulation of cytosolic ascorbate peroxidase (APX) by tyrosine nitration and S-nitrosylation. J Exp Bot 65(2):527–538

    Article  CAS  PubMed  Google Scholar 

  • Begara-Morales JC, Sánchez-Calvo B, Luque F, Leyva-Pérez MO, Leterrier M, Corpas FJ, Barroso JB (2014b) Differential transcriptomic analysis by RNA-seq of GSNO-responsive genes between Arabidopsis roots and leaves. Plant Cell Physiol 55(6):1080–1095

    Article  CAS  PubMed  Google Scholar 

  • Begara-Morales JC, Sánchez-Calvo B, Chaki M, Mata-Pérez C, Valderrama R, Padilla MN, López-Jaramillo J, Luque F, Corpas FJ, Barroso JB (2015) Differential molecular response of monodehydroascorbate reductase and glutathione reductase by nitration and S-nitrosylation. J Exp Bot 66(19):5983–5996

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Beigi F, Gonzalez DR, Minhas KM, Sun Q-A, Foster MW, Khan SA, Treuer AV, Dulce RA, Harrison RW, Saraiva RM (2012) Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function. Proc Natl Acad Sci 109(11):4314–4319

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Beligni MV, Laxalt AM, Lamattina L (1997) Putative role of nitric oxide in plant-pathogen interactions. In: Moncada S, Toda N, Higgs EA (eds) The biology of nitric oxide, Part 6. Portland Press, London, 250p

    Google Scholar 

  • Benhar M, Forrester MT, Hess DT, Stamler JS (2008) Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 320(5879):1050–1054

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Benhar M, Forrester MT, Stamler JS (2009) Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol 10(10):721–732

    Article  CAS  PubMed  Google Scholar 

  • Cao Y, Gomes SA, Rangel EB, Paulino EC, Fonseca TL, Li J, Teixeira MB, Gouveia CH, Bianco AC, Kapiloff MS (2015) S-nitrosoglutathione reductase-dependent PPARγ denitrosylation participates in MSC-derived adipogenesis and osteogenesis. J Clin Invest 125(4):1679–1691

    Article  PubMed  PubMed Central  Google Scholar 

  • Chaki M, Fernández-Ocaña AM, Valderrama R, Carreras A, Esteban FJ, Luque F, Gómez-Rodríguez MV, Begara-Morales JC, Corpas FJ, Barroso JB (2009) Involvement of reactive nitrogen and oxygen species (RNS and ROS) in sunflower-mildew interaction. Plant Cell Physiol 50(2):265–279

    Article  CAS  PubMed  Google Scholar 

  • Chaki M, Kovacs I, Spannagl M, Lindermayr C (2014) Computational prediction of candidate proteins for S-nitrosylation in Arabidopsis thaliana. PLoS One 9(10):e110232

    Article  PubMed  PubMed Central  Google Scholar 

  • Chen R, Sun S, Wang C, Li Y, Liang Y, An F, Li C, Dong H, Yang X, Zhang J (2009) The Arabidopsis PARAQUAT RESISTANT2 gene encodes an S-nitrosoglutathione reductase that is a key regulator of cell death. Cell Res 19(12):1377–1387

    Article  CAS  PubMed  Google Scholar 

  • Corpas FJ, Chaki M, Fernández-Ocaña A, Valderrama R, Palma JM, Carreras A, Begara-Morales JC, Airaki M, del Río LA, Barroso JB (2008) Metabolism of reactive nitrogen species in pea plants under abiotic stress conditions. Plant Cell Physiol 49(11):1711–1722

    Article  CAS  PubMed  Google Scholar 

  • Corpas FJ, Leterrier M, Valderrama R, Airaki M, Chaki M, Palma JM, Barroso JB (2011) Nitric oxide imbalance provokes a nitrosative response in plants under abiotic stress. Plant Sci 181(5):604–611

    Article  CAS  PubMed  Google Scholar 

  • Corrales FJ, Ruiz F, Mato JM (1999) In vivo regulation by glutathione of methionine adenosyltransferase S-nitrosylation in rat liver. J Hepatol 31(5):887–894

    Article  CAS  PubMed  Google Scholar 

  • Correa-Aragunde N, Cejudo FJ, Lamattina L (2015) Nitric oxide is required for the auxin-induced activation of NADPH-dependent thioredoxin reductase and protein denitrosylation during root growth responses in Arabidopsis. Ann Bot 116(4):695–702

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Delledonne M, Xia Y, Dixon RA, Lamb C (1998) Nitric oxide functions as a signal in plant disease resistance. Nature 394(6693):585–588

    Article  CAS  PubMed  Google Scholar 

  • Delledonne M, Zeier J, Marocco A, Lamb C (2001) Signal interactions between nitric oxide and reactive oxygen intermediates in the plant hypersensitive disease resistance response. Proc Natl Acad Sci 98(23):13454–13459

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dubreuil-Maurizi C, Poinssot B (2012) Role of glutathione in plant signaling under biotic stress. Plant Signal Behav 7(2):210–212

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Durner J, Wendehenne D, Klessig DF (1998) Defense gene induction in tobacco by nitric oxide, cyclic GMP, and cyclic ADP-ribose. Proc Natl Acad Sci 95(17):10328–10333

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Feechan A, Kwon E, Yun B-W, Wang Y, Pallas JA, Loake GJ (2005) A central role for S-nitrosothiols in plant disease resistance. Proc Natl Acad Sci 102(22):8054–8059

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Foster MW, Hess DT, Stamler JS (2009) Protein S-nitrosylation in health and disease: a current perspective. Trends Mol Med 15(9):391–404

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Frendo P, Baldacci-Cresp F, Benyamina SM, Puppo A (2013) Glutathione and plant response to the biotic environment. Free Radic Biol Med 65:724–730

    Article  CAS  PubMed  Google Scholar 

  • Gill SS, Anjum NA, Hasanuzzaman M, Gill R, Trivedi DK, Ahmad I, Pereira E, Tuteja N (2012) Glutathione and glutathione reductase: a boon in disguise for plant abiotic stress defense operations. Plant Physiol Biochem 70:204–212

    Article  Google Scholar 

  • Gong B, Wen D, Wang X, Wei M, Yang F, Li Y, Shi Q (2015) S-nitrosoglutathione reductase-modulated redox signaling controls sodic alkaline stress responses in Solanum lycopersicum L. Plant Cell Physiol 56(4):790–802

    Article  CAS  PubMed  Google Scholar 

  • Grant JJ, Loake GJ (2000) Role of reactive oxygen intermediates and cognate redox signaling in disease resistance. Plant Physiol 124(1):21–30

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Greco TM, Hodara R, Parastatidis I, Heijnen HFG, Dennehy MK, Liebler DC, Ischiropoulos H (2006) Identification of S-nitrosylation motifs by site-specific mapping of the S-nitrosocysteine proteome in human vascular smooth muscle cells. Proc Natl Acad Sci 103(19):7420–7425

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gupta KJ, Fernie AR, Kaiser WM, van Dongen JT (2011) On the origins of nitric oxide. Trends Plant Sci 16(3):160–168

    Article  CAS  PubMed  Google Scholar 

  • Hogg N (2002) The biochemistry and physiology of S-nitrosothiols. Annu Rev Pharmacol Toxicol 42(1):585–600

    Article  CAS  PubMed  Google Scholar 

  • Holmes AJ, Williams DLH (2000) Reaction of ascorbic acid with S-nitrosothiols: clear evidence for two distinct reaction pathways. J Chem Soc Perkin Trans 2(8):1639–1644

    Article  Google Scholar 

  • Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G (1987) Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci 84(24):9265–9269

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jensen D, Belka G, Du Bois G (1998) S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme. Biochem J 331:659–668

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kinkema M, Fan W, Dong X (2000) Nuclear localization of NPR1 is required for activation of PR gene expression. Plant Cell 12(12):2339–2350

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Klepper L (1979) Nitric oxide (NO) and nitrogen dioxide (NO2) emissions from herbicide-treated soybean plants. Atmos Environ (1967) 13(4):537–542

    Article  CAS  Google Scholar 

  • Kneeshaw S, Gelineau S, Tada Y, Loake GJ, Spoel SH (2014) Selective protein denitrosylation activity of thioredoxin-h5 modulates plant immunity. Mol Cell 56(1):153–162

    Article  CAS  PubMed  Google Scholar 

  • Kovacs I, Lindermayr C (2013) Nitric oxide-based protein modification: formation and site-specificity of protein S-nitrosylation. Front Plant Sci 4:137

    PubMed  PubMed Central  Google Scholar 

  • Kovacs I, Durner J, Lindermayr C (2015) Crosstalk between nitric oxide and glutathione is required for NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1)-dependent defense signaling in Arabidopsis thaliana. New Phytol. doi:10.1111/nph.13502

    Article  PubMed  Google Scholar 

  • Kronenfeld G, Engelman R, Weisman-Shomer P, Atlas D, Benhar M (2015) Thioredoxin-mimetic peptides as catalysts of S-denitrosylation and anti-nitrosative stress agents. Free Radic Biol Med 79:138–146

    Article  CAS  PubMed  Google Scholar 

  • Kubienová L, Tichá T, Jahnová J, Luhová L, Mieslerovái B, Petrivalský M (2014) Effect of abiotic stress stimuli on S-nitrosoglutathione reductase in plants. Planta 239(1):139–146

    Article  PubMed  Google Scholar 

  • Kwon E, Feechan A, Yun B-W, Hwang B-H, Pallas JA, Kang J-G, Loake GJ (2012) AtGSNOR1 function is required for multiple developmental programs in Arabidopsis. Planta 236(3):887–900

    Article  CAS  PubMed  Google Scholar 

  • Laxalt A, Beligni MV, Lamattina L (1997) Nitric oxide preserves the level of chlorophyll in potato leaves infected by Phytophthora infestans. Eur J Plant Pathol 103(7):643–651

    Article  CAS  Google Scholar 

  • Lee U, Wie C, Fernandez BO, Feelisch M, Vierling E (2008) Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in Arabidopsis. Plant Cell 20(3):786–802

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Leterrier M, Chaki M, Airaki M, Valderrama R, Palma JM, Barroso JB, Corpas FJ (2011) Function of S-nitrosoglutathione reductase (GSNOR) in plant development and under biotic/abiotic stress. Plant Signal Behav 6(6):789–793

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lindermayr C, Sell S, Muller B, Leister D, Durner J (2010) Redox regulation of the NPR1-TGA1 system of Arabidopsis thaliana by nitric oxide. Plant Cell 22(8):2894–2907

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Liu L, Hausladen A, Zeng M, Que L, Heitman J, Stamler JS (2001) A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. Nature 410(6827):490–494

    Article  CAS  PubMed  Google Scholar 

  • Liu L, Yan Y, Zeng M, Zhang J, Hanes MA, Ahearn G, McMahon TJ, Dickfeld T, Marshall HE, Que LG (2004) Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell 116(4):617–628

    Article  CAS  PubMed  Google Scholar 

  • Malik SI, Hussain A, Yun B-W, Spoel SH, Loake GJ (2011) GSNOR-mediated de-nitrosylation in the plant defence response. Plant Sci 181(5):540–544

    Article  CAS  PubMed  Google Scholar 

  • Marino SM, Gladyshev VN (2010) Structural analysis of cysteine S-nitrosylation: a modified acid-based motif and the emerging role of trans-nitrosylation. J Mol Biol 395(4):844–859

    Article  CAS  PubMed  Google Scholar 

  • Meng T-C, Fukada T, Tonks NK (2002) Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol Cell 9(2):387–399

    Article  CAS  PubMed  Google Scholar 

  • Mitchell DA, Marletta MA (2005) Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine. Nat Chem Biol 1(3):154–158

    Article  CAS  PubMed  Google Scholar 

  • Moore JW, Loake GJ, Spoel SH (2011) Transcription dynamics in plant immunity. Plant Cell 23(8):2809–2820

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mou Z, Fan W, Dong X (2003) Inducers of plant systemic acquired resistance regulate NPR1 function through redox changes. Cell 113(7):935–944

    Article  CAS  PubMed  Google Scholar 

  • Noctor G, Mhamdi A, Chaouch S, Han YI, Neukermans J, Marquez-Garcia B, Queval G, Foyer CH (2012) Glutathione in plants: an integrated overview. Plant Cell Environ 35(2):454–484

    Article  CAS  PubMed  Google Scholar 

  • Noritake T, Kawakita K, Doke N (1996) Nitric oxide induces phytoalexin accumulation in potato tuber tissues. Plant Cell Physiol 37(1):113–116

    Article  CAS  Google Scholar 

  • Pajerowska-Mukhtar KM, Emerine DK, Mukhtar MS (2013) Tell me more: roles of NPRs in plant immunity. Trends Plant Sci 18(7):402–411

    Article  CAS  PubMed  Google Scholar 

  • Palmer RM, Ferrige AG, Moncada S (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327(6122):524–526

    Article  CAS  PubMed  Google Scholar 

  • Qian J, Chen F, Kovalenkov Y, Pandey D, Moseley MA, Foster MW, Black SM, Venema RC, Stepp DW, Fulton DJR (2012) Nitric oxide reduces NADPH oxidase 5 (Nox5) activity by reversible S-nitrosylation. Free Radic Biol Med 52(9):1806–1819

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Romero JM, Bizzozero OA (2009) Intracellular glutathione mediates the denitrosylation of protein nitrosothiols in the rat spinal cord. J Neurosci Res 87(3):701–709

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rustérucci C, Espunya MC, Díaz M, Chabannes M, Martínez MC (2007) S-nitrosoglutathione reductase affords protection against pathogens in Arabidopsis, both locally and systemically. Plant Physiol 143(3):1282–1292

    Article  PubMed  PubMed Central  Google Scholar 

  • Sengupta R, Holmgren A (2012) The role of thioredoxin in the regulation of cellular processes by S-nitrosylation. Biochim Biophys Acta Gen Sub 1820(6):689–700

    Article  CAS  Google Scholar 

  • Shi Y-F, Wang D-l, Wang C, Culler AH, Kreiser MA, Suresh J, Cohen JD, Pan J, Baker B, Liu J-Z (2015) Loss of GSNOR1 function leads to compromised auxin signaling and polar auxin transport. Mol Plant 8(9):1350–1365

    Article  CAS  PubMed  Google Scholar 

  • Siddiqui MH, Al-Whaibi MH, Basalah MO (2011) Role of nitric oxide in tolerance of plants to abiotic stress. Protoplasma 248(3):447–455

    Article  CAS  PubMed  Google Scholar 

  • Smith BC, Marletta MA (2012) Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling. Curr Opin Chem Biol 16(5):498–506

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Spadaro D, Yun B-W, Spoel SH, Chu C, Wang Y-Q, Loake GJ (2010) The redox switch: dynamic regulation of protein function by cysteine modifications. Physiol Plant 138(4):360–371

    Article  CAS  PubMed  Google Scholar 

  • Staab CA, Hellgren M, Höög JO (2008) Medium-and short-chain dehydrogenase/reductase gene and protein families: dual functions of alcohol dehydrogenase 3: implications with focus on formaldehyde dehydrogenase and S-nitrosoglutathione reductase activities. Cell Mol Life Sci 65(24):3950–3960

    Article  CAS  PubMed  Google Scholar 

  • Stamler JS, Toone EJ, Lipton SA, Sucher NJ (1997) (S) NO signals: translocation, regulation, and a consensus motif. Neuron 18(5):691–696

    Article  CAS  PubMed  Google Scholar 

  • Strittmatter P, Ball EG (1955) Formaldehyde dehydrogenase, a glutathione-dependent enzyme system. J Biol Chem 213(1):445–461

    Article  CAS  PubMed  Google Scholar 

  • Tada Y, Spoel SH, Pajerowska-Mukhtar K, Mou Z, Song J, Wang C, Zuo J, Dong X (2008) Plant immunity requires conformational charges of NPR1 via S-nitrosylation and thioredoxins. Science 321(5891):952–956

    Article  CAS  PubMed  Google Scholar 

  • Terrile MC, París R, Calderón-Villalobos LIA, Iglesias MJ, Lamattina L, Estelle M, Casalongué CA (2012) Nitric oxide influences auxin signaling through S-nitrosylation of the Arabidopsis TRANSPORT INHIBITOR RESPONSE 1 auxin receptor. Plant J 70(3):492–500

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wang Y-Q, Feechan A, Yun B-W, Shafiei R, Hofmann A, Taylor P, Xue P, Yang F-Q, Xie Z-S, Pallas JA (2009) S-nitrosylation of AtSABP3 antagonizes the expression of plant immunity. J Biol Chem 284(4):2131–2137

    Article  CAS  PubMed  Google Scholar 

  • Wu C, Parrott AM, Liu T, Jain MR, Yang Y, Sadoshima J, Li H (2011) Distinction of thioredoxin transnitrosylation and denitrosylation target proteins by the ICAT quantitative approach. J Proteomics 74(11):2498–2509

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Xu S, Guerra D, Lee U, Vierling E (2013) S-nitrosoglutathione reductases are low-copy number, cysteine-rich proteins in plants that control multiple developmental and defense responses in Arabidopsis. Front Plant Sci 4:430

    Article  PubMed  PubMed Central  Google Scholar 

  • Yu M, Yun B-W, Spoel SH, Loake GJ (2012) A sleigh ride through the SNO: regulation of plant immune function by protein S-nitrosylation. Curr Opin Plant Biol 15(4):424–430

    Article  CAS  PubMed  Google Scholar 

  • Yu M, Lamattina L, Spoel SH, Loake GJ (2014) Nitric oxide function in plant biology: a redox cue in deconvolution. New Phytol 202(4):1142–1156

    Article  CAS  PubMed  Google Scholar 

  • Yun B-W, Spoel SH, Loake GJ (2011) Synthesis of and signalling by small, redox active molecules in the plant immune response. Biochim Biophys Acta Gen Sub 1820(6):770–776

    Article  Google Scholar 

  • Zaffagnini M, Morisse S, Bedhomme M, Marchand CH, Festa M, Rouhier N, Lemaire SD, Trost P (2013) Mechanisms of nitrosylation and denitrosylation of cytoplasmic glyceraldehyde-3-phosphate dehydrogenase from Arabidopsis thaliana. J Biol Chem 288(31):22777–22789

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

JBM would like to thank Alfonso Martín Escudero Foundation for funding his postdoctoral fellowship.

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  1. Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, King’s Buildings, Edinburgh, EH9 3JR, UK

    J. C. Begara-Morales & G. J. Loake

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  1. J. C. Begara-Morales
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Correspondence to G. J. Loake .

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  1. Universidad Nacional de Mar del Plata-CONICET, Instituto de Investigaciones Biológicas, Mar del Plata, Argentina

    Lorenzo Lamattina

  2. Universidad Nacional de Mar del Plata-CONICET, Instituto de Investigaciones Biológicas, Mar del Plata, Argentina

    Carlos García-Mata

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Begara-Morales, J.C., Loake, G.J. (2016). Protein Denitrosylation in Plant Biology. In: Lamattina, L., García-Mata, C. (eds) Gasotransmitters in Plants. Signaling and Communication in Plants. Springer, Cham. https://doi.org/10.1007/978-3-319-40713-5_10

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