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Hematopoietic Stem Cell Transplantation and Cardiotoxicity

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Manual of Cardio-oncology

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Abstract

Hematopoietic stem cell transplantation (HCT) is now used worldwide in the treatment of many malignant and non-malignant hematologic disorders and in the treatment of various solid tumors. Every year, many thousands of patients receive an autologous or allogeneic transplant procedure. Cardiac complications associated with HCT have been documented in several series, but the incidence of reported cardiotoxicity has varied largely among investigators, ranging from 2% to 28% probably reflecting patient selection, differences in HCT conditioning regimens and lack of universal grading system for cardiotoxic events.This chapter will focus on the cardiac complications occurring either in the early period following HCT or in the long-term phase.

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Authors and Affiliations

  1. Dipartimento di Ematologia, Medicina Trasfusionale e Biotecnologie, Unità di Terapia Intensiva Ematologica per il Trapianto Emopoietico, Ospedale Civile, Pescara, Italy

    Annalisa Natale, Stella Santarone & Paolo Di Bartolomeo

Authors
  1. Annalisa Natale
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  2. Stella Santarone
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  3. Paolo Di Bartolomeo
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Correspondence to Paolo Di Bartolomeo .

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Editors and Affiliations

  1. Cardiology Unit, IRCCS CRO-National Cancer Institute, Aviano (PN), Italy

    Chiara Lestuzzi

  2. Cardiology Unit, National Cancer Institute “Giovanni Paolo II”, Bari, Italy

    Stefano Oliva

  3. Medical Oncology Unit, Ospedale San Vincenzo, Taormina, Italy

    Francesco Ferraù

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Natale, A., Santarone, S., Di Bartolomeo, P. (2017). Hematopoietic Stem Cell Transplantation and Cardiotoxicity. In: Lestuzzi, C., Oliva, S., Ferraù, F. (eds) Manual of Cardio-oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-40236-9_16

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  • DOI: https://doi.org/10.1007/978-3-319-40236-9_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-40234-5

  • Online ISBN: 978-3-319-40236-9

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