Abstract
The extension of Chargaff’s second rule, also called the DNA symmetry, is pointed as an universal law present in the genomes of species. Previously, a measure of the symmetry above that expected in independence contexts (exceptional symmetry) was proposed to evaluate the phenomenon globally. The global exceptional symmetry was found in several species. However, the analysis of exceptional symmetry by word was not studied in detail. In this work a new exceptional symmetry measure is proposed to evaluate the exceptional symmetry effect by symmetric word pair. We develop a detailed study of the exceptional symmetry by symmetric pairs. We also discuss the exceptional symmetry by symmetric word pair for several organisms: 7 viruses; 5 archaea; 5 bacteria; 14 eukaryotes.
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Afreixo, V., Rodrigues, J.M.O.S., Bastos, C.A.C., Silva, R.M. (2016). Exceptional Symmetry Profile: A Genomic Word Analysis. In: Saberi Mohamad, M., Rocha, M., Fdez-Riverola, F., Domínguez Mayo, F., De Paz, J. (eds) 10th International Conference on Practical Applications of Computational Biology & Bioinformatics. PACBB 2016. Advances in Intelligent Systems and Computing, vol 477. Springer, Cham. https://doi.org/10.1007/978-3-319-40126-3_16
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DOI: https://doi.org/10.1007/978-3-319-40126-3_16
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