Alternative Vascular Access in Fetus

  • Guiti Milani
  • Younes BoudjemlineEmail author


Fetal echocardiography leads to the development of antenatal diagnosis [1]. In antenatal cardiology, proofs of evolution of congenital defect have been made: serial scans performed on fetuses with aortic valve disease demonstrated poor evolution of the left ventricle in some cases, leading to the concept of evolving hypoplastic left heart syndrome [2–4].


Fetal Heart Hypoplastic Left Heart Syndrome Aortic Valve Disease Antenatal Diagnosis Fetal Sheep 
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  1. 1.
    Kovalchin JP, Silverman NH. The impact of fetal echocardiography. Pediatr Cardiol. 2004;25:299–306.CrossRefPubMedGoogle Scholar
  2. 2.
    Trines J, Hornberger LK. Evolution of congenital heart disease in utero. Pediatr Cardiol. 2004;25:287–98.CrossRefPubMedGoogle Scholar
  3. 3.
    Hornberger LK, Need L, Benacerraf BR. Development of significant left and right ventricular hypoplasia in the second and third trimester fetus. J Ultrasound Med. 1996;15:655–9.PubMedGoogle Scholar
  4. 4.
    Hornberger LK, Sanders SP, Rein AJ, Spevak PJ, Parness IA, Colan SD. Left heart obstructive lesions and left ventricular growth in the mid trimester fetus: a longitudinal study. Circulation. 1995;92:1531–8.CrossRefPubMedGoogle Scholar
  5. 5.
    Maxwell D, Allan L, Tynan MJ. Balloon dilatation of the aortic valve in the fetus: a report of two cases. Br Heart J. 1991;65:256–8.CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    Tworetzky W, Wilkins-Haug L, Jennings R, van der Velde M, Marshall A, Marx G, Colan S, Benson C, Lock J, Perry S. Balloon dilation of severe aortic stenosis in the fetus potential for prevention of hypoplastic left heart syndrome candidate selection, technique, and results of successful intervention. Circulation. 2004;110:2125–31.CrossRefPubMedGoogle Scholar
  7. 7.
    Mäkikallio K, McElhinney DB, Levine JC, et al. Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal intervention. Circulation. 2006;113:1401–5.CrossRefPubMedGoogle Scholar
  8. 8.
    Daffos F, Capella-Pavlovsky M, Forestier F. Direct collection of fetal blood from the umbilical vein under echography. First results, prospects. Presse Med. 1983;12:1017.PubMedGoogle Scholar
  9. 9.
    Kohl T, Szabo Z, Suda K, Petrossian E, Ko E, Kececioglu D, Moore P, Silverman NH, Harrison MR, Chou TM, Hanley FL. Fetoscopic and open transumbilical fetal cardiac catheterization in sheep: potential approaches for human fetal cardiac intervention. Circulation. 1997;95:1048–53.CrossRefPubMedGoogle Scholar
  10. 10.
    Moise Jr KJ. Management of rhesus alloimmunization in pregnancy. Obstet Gynecol. 2008;112:164–76.CrossRefPubMedGoogle Scholar
  11. 11.
    McElhinney D, Tworetzky W, Lock J. Current status of fetal cardiac intervention. Circulation. 2010;121:1256–63.CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Kohl T, Strumper D, Witteler R, Merschhoff G, Alexiene R, Callenbeck C, Asfour B, Reckers J, Aryee S, Vahlhaus C, Vogt J, Van Aken H, Scheld HH. Fetoscopic direct fetal cardiac access in sheep: an important experimental milestone along the route to human fetal cardiac intervention. Circulation. 2000;102:1602–4.CrossRefPubMedGoogle Scholar
  13. 13.
    Jouannic JM, Boudjemline Y, Benifla JL, Bonnet D. Transhepatic ultrasound-guided cardiac catheterization in the fetal lamb. A new approach for cardiac interventions in fetuses. Circulation. 2005;111:736–41.CrossRefPubMedGoogle Scholar
  14. 14.
    Shim D, Lloyd TR, Cho KJ, et al. Transhepatic cardiac catheterization in children: evaluation of efficacy and safety. Circulation. 1995;92:1526–30.CrossRefPubMedGoogle Scholar
  15. 15.
    Edwards A, Veldman A, Nitsos I, Chan Y, Brew N, Teoh M, Menahem S, Schranz D, Wong F. A percutaneous fetal cardiac catheterization technique for pulmonary valvuloplasty and valvulotomy in a mid-gestation lamb model. Prenat Diagn. 2015;35:74–80.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Cardiologie Pédiatrique, Centre de Référence Malformations Cardiaques Congénitales Complexes – M3CNecker Hospital for Sick Children, Assistance Publique des Hôpitaux de ParisParisFrance
  2. 2.Université Paris V DescartesParisFrance

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