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Stem Cell Processing pp 107–129Cite as

Production of Clinical-Grade Mesenchymal Stem Cells

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Part of the book series: Stem Cells in Clinical Applications ((SCCA))

Abstract

Recent clinical applications of stem cells have demonstrated novel therapies for chronic diseases and certain kinds of cancers. The first clinical case was treated with hematopoietic stem cells over 50 years ago. Subsequently, mesenchymal stem cells (MSCs) have been clinically applied to various diseases. Furthermore, induced pluripotent stem cells were first clinically used in the last year. Some reports suggest that clinical applications of stem cells will increase from 2017 to 2020. One important requirement for the clinical usage of stem cells is the production of stem cells. The quality of stem cells significantly affects the treatment efficiency. This chapter presents some guidelines for MSC production according to good manufacturing practice (GMP) that helps to maintain the quality of stem cells from batch to batch as well as the clinical satisfaction. Because of the advantages of MSCs, these cells may become the most popular type of stem cells for clinical applications in the near future.

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Author information

Authors and Affiliations

  1. Laboratory of Stem Cell Research and Application, University of Science, Vietnam National University, Ho Chi Minh City, Vietnam

    Phuc Van Pham & Ngoc Bich Vu

  2. Biology-Biotechnology Faculty, University of Science, Vietnam National University, Ho Chi Minh City, Vietnam

    Phuc Van Pham

Authors
  1. Phuc Van Pham
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  2. Ngoc Bich Vu
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Correspondence to Phuc Van Pham .

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Editors and Affiliations

  1. Laboratory of Stem Cell Research and Application, University of Science Vietnam National University, Ho Chi Minh City, Vietnam

    Phuc Van Pham

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© 2016 Springer International Publishing Switzerland

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Van Pham, P., Vu, N.B. (2016). Production of Clinical-Grade Mesenchymal Stem Cells. In: Pham, P. (eds) Stem Cell Processing . Stem Cells in Clinical Applications. Springer, Cham. https://doi.org/10.1007/978-3-319-40073-0_6

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