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The Thrombosed Hemodialysis Access

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Hemodialysis Access

Abstract

Vascular access is a lifeline for end-stage renal disease patients. The National Kidney Foundation-Kidney Dialysis Outcomes Quality Initiative (NKF-KDOQI) published practice guidelines that recommend all patients with stage IV or stage V chronic kidney disease to undergo fistula creation [1]. The guidelines also included an order of preference for AV access procedures in order to preserve viable access sites. The recommendations are based on autogenous fistulas having a superior patency than prosthetic grafts and tunneled catheters, as well as fewer complications and repeat interventions. Despite these recommendations, dialysis access fails and re-intervention is needed [2, 3]. While there are often signs that an access is failing, there are many options for both avoiding and treating the access failure as it occurs.

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References

  1. III. NKF-K/DOQI clinical practice guidelines for vascular access: update 2000. Am J Kidney Dis. 2001;37(1 Suppl 1):S137–81.

    Google Scholar 

  2. Albers FJ. Causes of hemodialysis access failure. Adv Ren Replace Ther. 1994;1(2):107–18.

    CAS  PubMed  Google Scholar 

  3. Brahmbhatt A, Misra S. The biology of hemodialysis vascular access failure. Semin Intervent Radiol. 2016;33(1):15–20.

    Article  PubMed  Google Scholar 

  4. Roy-Chaudhury P, et al. Venous neointimal hyperplasia in polytetrafluoroethylene dialysis grafts. Kidney Int. 2001;59(6):2325–34.

    Article  CAS  PubMed  Google Scholar 

  5. Porile JL, Richter M. Preservation of vascular access. J Am Soc Nephrol. 1993;4(4):997–1003.

    CAS  PubMed  Google Scholar 

  6. Bauer A, Limperger V, Nowak-Gottl U. End-stage renal disease and thrombophilia. Hamostaseologie. 2016;36(2):103–7.

    Google Scholar 

  7. Klamroth R, et al. The influence of thrombophilic risk factors on vascular access survival in chronic dialysis patients in a retrospective evaluation. Vasa. 2013;42(1):32–9.

    Article  PubMed  Google Scholar 

  8. Danis R, et al. Thrombophilias and arteriovenous fistula dysfunction in maintenance hemodialysis. J Thromb Thrombolysis. 2009;27(3):307–15.

    Article  PubMed  Google Scholar 

  9. Knoll GA, et al. Thrombophilia and the risk for hemodialysis vascular access thrombosis. J Am Soc Nephrol. 2005;16(4):1108–14.

    Article  PubMed  Google Scholar 

  10. Molino D, et al. Plasma levels of plasminogen activator inhibitor type 1, factor VIII, prothrombin activation fragment 1 + 2, anticardiolipin, and antiprothrombin antibodies are risk factors for thrombosis in hemodialysis patients. Semin Nephrol. 2004;24(5):495–501.

    Article  CAS  PubMed  Google Scholar 

  11. King DH, et al. Volume blood flow, static pressure ratio and venous conductance in native arterio-venous fistulae: three surveillance methods compared. J Vasc Access. 2015;16(3):211–7.

    Article  PubMed  Google Scholar 

  12. Paulson WD, Work J. Controversial vascular access surveillance mandate. Semin Dial. 2010;23(1):92–4.

    Article  PubMed  Google Scholar 

  13. White JJ, et al. Mathematical model demonstrates influence of luminal diameters on venous pressure surveillance. Clin J Am Soc Nephrol. 2007;2(4):681–7.

    Article  PubMed  Google Scholar 

  14. Sherman RA, Kapoian T. The role of recirculation in access monitoring. ASAIO J. 1998;44(1):40–1.

    Article  CAS  PubMed  Google Scholar 

  15. Roy-Chaudhury P, et al. Cellular phenotypes in human stenotic lesions from haemodialysis vascular access. Nephrol Dial Transplant. 2009;24(9):2786–91.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Lauvao LS, et al. Vein diameter is the major predictor of fistula maturation. J Vasc Surg. 2009;49(6):1499–504.

    Article  PubMed  Google Scholar 

  17. Maher J, et al. Massive arm edema following arteriovenous dialysis shunt creation in a patient with ipsilateral permanent pacemaker. J Clin Ultrasound. 2008;36(5):321–4.

    Article  PubMed  Google Scholar 

  18. Stone WJ, Wall MN, Powers TA. Massive upper extremity edema with arteriovenous fistula for hemodialysis. A complication of previous pacemaker insertion. Nephron. 1982;31(2):184–6.

    Article  CAS  PubMed  Google Scholar 

  19. Altman SD. A practical approach for diagnosis and treatment of central venous stenosis and occlusion. Semin Vasc Surg. 2007;20(3):189–94.

    Article  PubMed  Google Scholar 

  20. Napoli M, et al. Ultrasound guided brachial arterial angioplasty during the creation of a radio-cephalic arteriovenous fistula: a case report. J Vasc Access. 2006;7(1):38–42.

    CAS  PubMed  Google Scholar 

  21. Bojakowski K, et al. Preoperative ultrasonographic examination of the radial artery and the cephalic vein and risks of dialysis arterio-venous fistula dysfunction. Pol J Radiol. 2010;75(1):7–12.

    PubMed  PubMed Central  Google Scholar 

  22. Coentrao L, Faria B, Pestana M. Physical examination of dysfunctional arteriovenous fistulae by non-interventionalists: a skill worth teaching. Nephrol Dial Transplant. 2012;27(5):1993–6.

    Article  PubMed  Google Scholar 

  23. Schuman E, et al. Comparison of clinical assessment with ultrasound flow for hemodialysis access surveillance. Arch Surg. 2007;142(12):1129–33.

    Article  PubMed  Google Scholar 

  24. Tessitore N, et al. Clinical access assessment. J Vasc Access. 2014;15 Suppl 7:S20–7.

    PubMed  Google Scholar 

  25. Neville RF, et al. Venous hypertension associated with arteriovenous hemodialysis access. Semin Vasc Surg. 2004;17(1):50–6.

    Article  PubMed  Google Scholar 

  26. Sullivan KL, et al. Hemodynamics of failing dialysis grafts. Radiology. 1993;186(3):867–72.

    Article  CAS  PubMed  Google Scholar 

  27. Besarab A, et al. Venous access pressures and the detection of intra-access stenosis. ASAIO J. 1992;38(3):M519–23.

    Article  CAS  PubMed  Google Scholar 

  28. Moreno Sanchez T, et al. Value of doppler ultrasonography in the study of hemodialysis peripheral vascular access dysfunction. Radiologia. 2014;56(5):420–8.

    Article  CAS  PubMed  Google Scholar 

  29. Malik J, et al. Surveillance of arteriovenous accesses with the use of duplex Doppler ultrasonography. J Vasc Access. 2014;15 Suppl 7:S28–32.

    PubMed  Google Scholar 

  30. Bandyk DF. Interpretation of duplex ultrasound dialysis access testing. Semin Vasc Surg. 2013;26(2–3):120–6.

    Article  PubMed  Google Scholar 

  31. Scaffaro LA, et al. Maintenance of hemodialysis arteriovenous fistulas by an interventional strategy: clinical and duplex ultrasonographic surveillance followed by transluminal angioplasty. J Ultrasound Med. 2009;28(9):1159–65.

    PubMed  Google Scholar 

  32. Paulson WD, White JJ. Should arteriovenous fistulas and synthetic grafts undergo surveillance with pre-emptive correction of stenosis? Nat Clin Pract Nephrol. 2008;4(9):480–1.

    Article  PubMed  Google Scholar 

  33. Ram SJ, et al. A randomized controlled trial of blood flow and stenosis surveillance of hemodialysis grafts. Kidney Int. 2003;64(1):272–80.

    Article  PubMed  Google Scholar 

  34. Lumsden AB, et al. Cost efficacy of duplex surveillance and prophylactic angioplasty of arteriovenous ePTFE grafts. Ann Vasc Surg. 1998;12(2):138–42.

    Article  CAS  PubMed  Google Scholar 

  35. Asif A, et al. Inflow stenosis in arteriovenous fistulas and grafts: a multicenter, prospective study. Kidney Int. 2005;67(5):1986–92.

    Article  PubMed  Google Scholar 

  36. Paulson WD, et al. Inflow stenosis obscures recognition of outflow stenosis by dialysis venous pressure: analysis by a mathematical model. Nephrol Dial Transplant. 2008;23(12):3966–71.

    Article  PubMed  Google Scholar 

  37. Harp RJ, et al. Pulmonary hypertension among end-stage renal failure patients following hemodialysis access thrombectomy. Cardiovasc Intervent Radiol. 2005;28(1):17–22.

    Article  PubMed  Google Scholar 

  38. Turmel-Rodrigues LA. Hemodialysis graft declotting with the “lyse and wait” technique: a new name for an old recipe. J Vasc Interv Radiol. 1999;10(1):96–8.

    Article  CAS  PubMed  Google Scholar 

  39. Cynamon J, et al. Hemodialysis graft declotting: description of the “lyse and wait” technique. J Vasc Interv Radiol. 1997;8(5):825–9.

    Article  CAS  PubMed  Google Scholar 

  40. McCutcheon B, et al. A preliminary investigation of balloon angioplasty versus surgical treatment of thrombosed dialysis access grafts. Am Surg. 2003;69(8):663–7; discussion 668.

    PubMed  Google Scholar 

  41. Ko PJ, et al. Initial experience during balloon angioplasty assisted surgical thrombectomy for thrombosed hemodialysis grafts. Chang Gung Med J. 2003;26(3):178–83.

    PubMed  Google Scholar 

  42. Bitar G, Yang S, Badosa F. Balloon versus patch angioplasty as an adjuvant treatment to surgical thrombectomy of hemodialysis grafts. Am J Surg. 1997;174(2):140–2.

    Article  CAS  PubMed  Google Scholar 

  43. Schwartz CI, et al. Thrombosed dialysis grafts: comparison of treatment with transluminal angioplasty and surgical revision. Radiology. 1995;194(2):337–41.

    Article  CAS  PubMed  Google Scholar 

  44. Dapunt O, et al. Transluminal angioplasty versus conventional operation in the treatment of haemodialysis fistula stenosis: results from a 5-year study. Br J Surg. 1987;74(11):1004–5.

    Article  CAS  PubMed  Google Scholar 

  45. Tessitore N, et al. A prospective controlled trial on effect of percutaneous transluminal angioplasty on functioning arteriovenous fistulae survival. J Am Soc Nephrol. 2003;14(6):1623–7.

    Article  PubMed  Google Scholar 

  46. Cohen MA, et al. Improved treatment of thrombosed hemodialysis access sites with thrombolysis and angioplasty. Kidney Int. 1994;46(5):1375–80.

    Article  CAS  PubMed  Google Scholar 

  47. Kumpe DA, Cohen MA. Angioplasty/thrombolytic treatment of failing and failed hemodialysis access sites: comparison with surgical treatment. Prog Cardiovasc Dis. 1992;34(4):263–78.

    Article  CAS  PubMed  Google Scholar 

  48. Schwab SJ, et al. Transluminal angioplasty of venous stenoses in polytetrafluoroethylene vascular access grafts. Kidney Int. 1987;32(3):395–8.

    Article  CAS  PubMed  Google Scholar 

  49. Glanz S, et al. The role of percutaneous angioplasty in the management of chronic hemodialysis fistulas. Ann Surg. 1987;206(6):777–81.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  50. Smith TP, et al. Thrombosed synthetic hemodialysis access fistulas: the success of combined thrombectomy and angioplasty (technical note). AJR Am J Roentgenol. 1986;147(1):161–3.

    Article  CAS  PubMed  Google Scholar 

  51. Hunter DW, et al. Failing or thrombosed Brescia-Cimino arteriovenous dialysis fistulas. Angiographic evaluation and percutaneous transluminal angioplasty. Radiology. 1983;149(1):105–9.

    Article  CAS  PubMed  Google Scholar 

  52. Gaux JC, et al. Percutaneous transluminal angioplasty of stenotic lesions in dialysis vascular accesses. Eur J Radiol. 1983;3(3):189–93.

    CAS  PubMed  Google Scholar 

  53. Calsina L, et al. Treatment of arteriovenous haemodialysis graft thrombosis associated to venous anastomotic stenosis by surgical thrombectomy, covered stenting and high-pressure angioplasty. Nefrologia. 2013;33(4):564–70.

    PubMed  Google Scholar 

  54. Chan MG, et al. Evaluation of expanded polytetrafluoroethylene-covered stents for the treatment of venous outflow stenosis in hemodialysis access grafts. J Vasc Interv Radiol. 2011;22(5):647–53.

    Article  PubMed  Google Scholar 

  55. Shin BS, et al. Use of covered stents in the central vein: a feasibility study in a canine model. J Endovasc Ther. 2011;18(6):802–10.

    Article  PubMed  Google Scholar 

  56. Anaya-Ayala JE, et al. Efficacy of covered stent placement for central venous occlusive disease in hemodialysis patients. J Vasc Surg. 2011;54(3):754–9.

    Article  PubMed  Google Scholar 

  57. Sprouse 2nd LR, et al. Percutaneous treatment of symptomatic central venous stenosis [corrected]. J Vasc Surg. 2004;39(3):578–82.

    Article  PubMed  Google Scholar 

  58. Florescu MC, et al. Endovascular treatment of arteriovenous graft pseudoaneurysms, indications, complications, and outcomes: a systematic review. Hemodial Int. 2014;18(4):785–92.

    Article  PubMed  Google Scholar 

  59. Kershen LM, Marichal DA. Endovascular treatment of stent fracture and pseudoaneurysm formation in arteriovenous fistula dialysis access. Proc (Bayl Univ Med Cent). 2013;26(1):47–9.

    Google Scholar 

  60. Shah AS, et al. Endovascular treatment of hemodialysis access pseudoaneurysms. J Vasc Surg. 2012;55(4):1058–62.

    Article  PubMed  Google Scholar 

  61. Powell A, et al. Long-segment plication technique for arteriovenous fistulae threatened by diffuse aneurysmal degeneration: short-term results. Ann Vasc Surg. 2015;29(6):1327–31.

    Article  PubMed  Google Scholar 

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Correspondence to George H. Meier MD .

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Caldwell, E., Meier, G.H. (2017). The Thrombosed Hemodialysis Access. In: Shalhub, S., Dua, A., Shin, S. (eds) Hemodialysis Access. Springer, Cham. https://doi.org/10.1007/978-3-319-40061-7_35

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  • DOI: https://doi.org/10.1007/978-3-319-40061-7_35

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