Abstract
Breakpoint graph is a key data structure to study genome rearrangements. The problem of Breakpoint Graph Decomposition (BGD), which asks for a largest collection of edge-disjoint cycles in a breakpoint graph, is a crucial step in computing rearrangement distances between genomes. This problem for genomes of unsigned genes is proved NP-hard, and the best known approximation ratio is 1.4193+\(\epsilon \) [1]. In this paper, we present a polynomial time algorithm to detect whether a breakpoint graph can be decomposed into none other than 2-cycles. Our algorithm can be used to detect if there exists a sorting scenario between two genomes without reusing any breakpoints.
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Pu, L., Jiang, H. (2016). Can a Breakpoint Graph be Decomposed into None Other Than 2-Cycles?. In: Zhu, D., Bereg, S. (eds) Frontiers in Algorithmics. FAW 2016. Lecture Notes in Computer Science(), vol 9711. Springer, Cham. https://doi.org/10.1007/978-3-319-39817-4_20
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DOI: https://doi.org/10.1007/978-3-319-39817-4_20
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