Abstract
The urinary tract is commonly subjected to stressors that can result in atypical and suspicious findings in a voided urine specimen (see Table 8.1). The most common stressors include indwelling catheters, various toxins, ischemic changes, calculi, bladder and kidney infections, immune mediated cystitis, and inflammatory reactions to radiation therapy, immunotherapy and chemotherapy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Readings
Ubago JM, Mehta V, Wojcik EM, Barkan GA. Evaluation of atypical urine cytology progression to malignancy. Cancer Cytopathol. 2013;121:387–91.
Halling KC, Kipp BR. Bladder cancer detection using FISH (UroVysion assay). Adv Anat Pathol. 2008;15:279–86.
Tapia C, Glatz K, Obermann EC, et al. Evaluation of chromosomal aberrations in patients with benign conditions and reactive changes in urinary cytology. Cancer Cytopathol. 2011;119:404–10.
Rosenthal DL, Vandenbussche CJ, Burroughs FH, Sathiyamoorthy S, Guan H, Owens C. The Johns Hopkins Hospital template for urologic cytology samples: part I- creating the template. Cancer Cytopathol. 2013;121:15–20.
VandenBussche CJ, Sathiyamoorthy S, Owens CL, et al. The Johns Hopkins Hospital template for urologic cytology samples. Parts II and III improving the predictability of indeterminate results in urinary cytologic samples: an outcomes and cytomorphologic study. Cancer Cytopathol. 2013;121:21–8.
Voulgaris E, Pentheroudakis G, Pappa L, et al. Positive urinary cytology in patients with lung cancer in the absence of obvious urinary tract metastases. Lung Cancer. 2011;73:51–8.
Bostwick DG, Hossain D. Does subdivision of the “atypical” urine cytology increase predictive accuracy for urothelial carcinoma? Diagn Cytopathol. 2014;42:1034–44.
Kryvenko ON, Epstein JI. Pseudocarcinomatous urothelial hyperplasia of the bladder: clinical findings and follow-up of 70 patients. J Urol. 2013;189:2083–6.
Farinola MA, Lawler LP, Rosenthal DL. Plasmacytoma with involvement of the urinary bladder: report of a case diagnosed by urine cytology. Acta Cytol. 2003;47(5):787–91.
Florescu MC, Miles CD, Florescu DF. What do we know about adenovirus in renal transplantation? Nephrol Dial Transplant. 2013;28:2003–10.
Goldstein ML, Whitman T, Renshaw AA. Significance of cell groups in voided urine. Acta Cytol. 1998;42:290–4.
Guan H, Rosenthal DL, Erozan YS. Mullerianosis of the urinary bladder: report of a case with diagnosis suggested in urine cytology and review of the literature. Diagn Cytopathol. 2012;40:997–1001.
Vergara-Lluri ME, Hu E, Rao J-Y, et al. Comparative evaluation of ProEx C and ImmunoCyt/uCyt assays in atypical urine cytology. Arch Pathol Lab Med. 2014;138:1215–22.
Mokhtar GA, Al-Dousari M, Al-Ghamedi D. Diagnostic significance of atypical category in the voided urine samples: a retrospective study in a tertiary care center. Urol Ann. 2010;2:100–6.
Yoshida K, Ishida M, Kagotani A, et al. Small cell carcinoma of the urinary bladder and prostate: cytological analyses of four cases with emphasis on the usefulness of cytological examination. Oncol Lett. 2014;7:369–72.
Nabi G, Greene D, Donnel MO. Suspicious urinary cytology with negative evaluation for malignancy in the diagnostic investigation of hematuria: how to follow up? J Clin Pathol. 2004;57:365–8.
Deshpande V, McKee GT. Analysis of atypical urine cytology in a tertiary care center. Cancer Cytopathol. 2005;105:468–75.
Piaton E, Decaussin-Petrucci M, Mege-Lechevallier F, et al. Diagnostic terminology for urinary cytology reports including the new subcategories ‘atypical urothelial cells of undetermined significance (AUC-US) and ‘cannot exclude high grade’ (AUC-H). Cytopathology. 2014;25:27–38.
Ton Nu TN, Kassouf W, Ahmadi-Kaliji B, et al. The value of the ‘suspicious for urothelial carcinoma’ cytology category : a correlative study of 4 years including 337 patients. Cancer Cytopathol. 2014;122:796–803.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Samedi, V.G., Bocklage, T. (2016). Urinary Tract Cytology. In: Pitfalls in Diagnostic Cytopathology With Key Differentiating Cytologic Features. Essentials in Cytopathology, vol 27. Springer, Cham. https://doi.org/10.1007/978-3-319-39809-9_8
Download citation
DOI: https://doi.org/10.1007/978-3-319-39809-9_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-39807-5
Online ISBN: 978-3-319-39809-9
eBook Packages: MedicineMedicine (R0)