Abstract
This subsection focuses on perceived abnormalities of osseous overgrowth or prominent protuberances that are within normal limits or are not atypical in certain age groups (e.g., benign hyperostosis frontalis in middle-aged females). This also includes perceived abnormalities of calvarial contour or multifocal irregularities in adults that may simulate disease. Many disease states that cause diffuse bony overgrowth are not covered here except as an occasional comparison case, since there can be a myriad causes/diseases for this appearance that range from malignant neoplastic (e.g., diffuse metastatic disease), benign (e.g., fibrous dysplasia), or metabolic (e.g., Paget disease or thalassemia).
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McKinney, A.M. (2017). Normal Variations in Calvarial Contour, Irregular Ossification/Aeration, and Inward/Outward Projections/Protuberances. In: Atlas of Normal Imaging Variations of the Brain, Skull, and Craniocervical Vasculature . Springer, Cham. https://doi.org/10.1007/978-3-319-39790-0_29
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