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The Examination, Differential Diagnosis, and Management of Toothache Pain

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Abstract

The most common reason given for dental emergencies is a toothache. This pain is usually associated with dental caries which has caused inflammation in the dental pulp and/or progressed into the periradicular region. Pulpal and periradicular diagnoses contribute to more than 90 % of reported toothache pain. Dental emergencies can be treated efficiently, and pain relief can be provided. There exists a significant subset of reported toothache pain which is not associated with caries, pulpal, or periradicular structures. Patients in this subset are reported to have experienced little or no relief of their pain as they have received different dental procedures including endodontic and exodontia often without a clear diagnosis. There are three other main groups of diagnoses that need to be considered in addition to the pulpal and periradicular diagnoses: referred pain, neuropathic pain, and nonodontogenic pain. A dilemma may occur when diagnostic criteria are not well understood, the signs and symptoms are not a clear match for any diagnostic criteria, and when health-care practitioners provide treatment without a clear diagnosis.

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References

  • Abd-Elmeguid A, Yu DC. Dental pulp neurophysiology: part 1. Clinical and diagnostic implications. J Can Dent Assoc. 2009;75(1):55–9.

    PubMed  Google Scholar 

  • Allerbring M, Haegerstam G. Chronic idiopathic orofacial pain. A long-term follow-up study. Acta Odontol Scand. 2004;62(2):66–9.

    Article  PubMed  Google Scholar 

  • Alonso AA, Nixdorf DR. Case series of four different headache types presenting as tooth pain. J Endod. 2006;32(11):1110–3.

    Article  PubMed  Google Scholar 

  • Argoff CE. Recent developments in the treatment of osteoarthritis with NSAIDS. Curr Med Res Opin. 2011;27(7):1315–27.

    Article  PubMed  Google Scholar 

  • Battrum DE, Gutmann JL. Phantom tooth pain: a diagnosis of exclusion. Int Endod J. 1996;29:190–4.

    Article  PubMed  Google Scholar 

  • Bender IB. Pulpal pain diagnosis – a review. J Endod. 2000;26(3):175–9.

    Article  PubMed  Google Scholar 

  • Boeira GF, Correa MB, Peres KG, Peres MA, Santos IS, Matijasevich A, Barros AJ, Dmarco FF. Caries is the main cause for dental pain in childhood: finding from birth cohort. Caries Res. 2012;46(5):488–95.

    Article  PubMed  Google Scholar 

  • Clark GT. Persistent orodental pain, atypical odontalgia, and phantom tooth pain: when are they neuropathic disorders? CDA J. 2006;34(8):599–609.

    Google Scholar 

  • De Siqueira SR, Nóbrega JC, Valle LB, et al. Idiopathic trigeminal neuralgia: clinical aspects and dental procedures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;98:311–5.

    Article  PubMed  Google Scholar 

  • DeAngelis AF, Chambers IG, Hall GM. Temporomandibular joint disorders in patients referred for third molar extraction. Aust Dent J. 2009;54:323–5.

    Article  PubMed  Google Scholar 

  • Docampo J, Gonzalez N, Muňoz A, et al. Neurovascular study of the trigeminal nerve at 3 T MRI. Neuroradiol J. 2015;28(1):28–35.

    PubMed  PubMed Central  Google Scholar 

  • Ehrmann EH. The diagnosis of referred orofacial dental pain. Aust Endod J. 2002;28(2):75–81.

    Article  PubMed  Google Scholar 

  • Ekanayake L, Weerasekare C, Ekanayake N. Needs and demands for dental care in patients attending University Dental Hospital in Sri Lanka. Int Dent J. 2001;51(2):67–72.

    Article  PubMed  Google Scholar 

  • Ferguson J. Rhinosinusitis in oral medicine and dentistry. Aust Dent J. 2014;59:289–95.

    Article  PubMed  Google Scholar 

  • Fernandez-de-las-Peñas C, et al. Bilateral widespread mechanical sensitivity in women with myofascial temporomandibular disorder: evidence of impairment in central nociceptive processing. J Pain. 2009;10(11):1170–8.

    Article  PubMed  Google Scholar 

  • Files DK, Jausurawong T, Katrajian R, Danoff R. Multiple sclerosis. Prim Care Clin Office Pract. 2015;42:159–75.

    Article  Google Scholar 

  • Fricton J. Myogenous temporomandibular disorders: diagnostic and management considerations. Dent Clin N Am. 2007;51:61–83.

    Article  PubMed  Google Scholar 

  • Fricton J. Temporomandibular disorders: a human systems approach. CDA J. 2014;42(8):523–32.

    Google Scholar 

  • Friend LA, Glenwright HD. An experimental investigation into the localization of pain from the dental pulp. Oral Surg Oral Med Oral Pathol. 1968;25(5):765–74.

    Article  PubMed  Google Scholar 

  • Ge HY, Wang K, Madeline P, Svensson P, Sessle BJ, Arendt-Nielsen L. Simultaneous modulation of exteroceptive suppression periods in the trapezius and temporalis muscles by experimental muscle pain. Clin Neurophysiol. 2004;115:1399–408.

    Article  PubMed  Google Scholar 

  • Handa T, Fukuda K, Ichinohe T. Effect of combination of trigger point injection and stellate ganglion block on non-odontogenic mandibular molar pain referred from masseter muscle: a case report. Bull Tokyo Dent Coll. 2013;54(3):171–5.

    Article  PubMed  Google Scholar 

  • Iqbal M, Kim S, Yoon F. An investigation into differential diagnosis of pulp and periapical pain: a PennEndo database study. J Endod. 2007;33(5):548–51.

    Article  PubMed  Google Scholar 

  • Kreiner M, Okeson JP, Michelis V, et al. Craniofacial pain as the sole symptom of cardiac ischemia: a prospective multicenter study. J Am Dent Assoc. 2007;138(1):74–9.

    Article  PubMed  Google Scholar 

  • Lacerda JT, Simioinato EM, Peres KG, Traebert J, Marcenes W. Dental pain as the reason for visiting a dentist in a Brazilian adult population. Rev Saude Publica. 2004;38(3):453–8.

    Article  PubMed  Google Scholar 

  • Linn J, Trantor I, Teo N, Thanigaivel R, Goss AN. The differential diagnosis of toothache from other orofacial pains in clinical practice. Aust Dent J. 2007;52(1 suppl):S100–4.

    Article  PubMed  Google Scholar 

  • Lopez-Lopez J, Adserias-Garriga MJ, Garcia-Vicente L, et al. Orofacial pain of cardiac origin, serial of clinical cases. Med Oral Patol Oral Cir Bucal. 2012;17(4):e633–7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Mandel L. Salivary gland disorders. Dent Clin N Am. 2011;55(1):121–40.

    Article  PubMed  Google Scholar 

  • Masunobu T, Kurioka T, Miyagawa Y, et al. Minimally invasive surgery of sialolithiasis using sialendoscopy. Auris Nasus Larynx. 2014;41(6):528–31.

    Article  Google Scholar 

  • McCarthy JP, McClanahan S, Hodges J, Bowles WR. Frequency of localization of the painful tooth by patients presenting for an endodontic emergency. J Endod. 2010;36(5):801–5.

    Article  PubMed  Google Scholar 

  • Nixdorf DR, Moana-Filho EJ, Law AS, et al. Frequency of persistent tooth pain after root canal therapy: a systematic review and meta-analysis. J Endod. 2010;36(2):224–30.

    Article  PubMed  PubMed Central  Google Scholar 

  • Okeson J. Joint intracapsular disorders: diagnostic and nonsurgical management considerations. Dent Clin N Am. 2007;51:85–103.

    Article  PubMed  Google Scholar 

  • Oliveira LG, Hurst ND, Magajna PW. Bedside emergency ultrasound in a case of acute parotid duct sialolithiasis. J Emerg Med. 2014;47(2):e49–51.

    Article  PubMed  Google Scholar 

  • Oshima K, Ishii T, Ogura Y, et al. Clinical investigation of patients who develop neuropathic tooth pain after endodontic procedures. J Endod. 2009;35(7):958–61.

    Article  PubMed  Google Scholar 

  • Romero-Reyes M, Uyanik JM. Orofacial pain management: current perspectives. J Pain Res. 2014;7:99–115.

    Article  PubMed  PubMed Central  Google Scholar 

  • Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, et al. Clinical practice guideline (update): adult sinusitis. Otolaryngol Head Neck Surg. 2015;152(2S):S1–39.

    PubMed  Google Scholar 

  • Sato J, Saitoh T, Notani KI, et al. Diagnostic significance of carbamazepine and trigger zones in trigeminal neuralgia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97:18–22.

    Article  PubMed  Google Scholar 

  • Tordik PA, Webb TD, Weber CD. Pulpal and apical diagnosis. Clin Update Navl Postgrad Dental School. 2010;32(2):1–2.

    Google Scholar 

  • Venskutonis T, Daugela P, Strazdas M, Juodzbalys G. Accuracy of digital radiography and cone beam computed tomography on periapical radiolucency detection in endodontically treated teeth. J Oral Maxillofac Res. 2014;5(2):1–7.

    Article  Google Scholar 

  • Von Eckardstein KL, Keil M, Rohde V. Unnecessary dental procedures as a consequence of trigeminal neuralgia. Neurosurg Rev. 2014. doi:10.1007/s10143-014-0591-1.

    Google Scholar 

  • Willison HJ, Jacobs BC, van Doorn PA. Guillain-Barré syndrome. 2016. The Lancet Published online Feb 29, doi:10.1016/S0140-6736(16)00339-1.

  • Woolf CJ. Central sensitization: implications for the diagnosis and treatment of pain. Pain. 2011;152(3 Suppl):S2–15.

    Article  PubMed  Google Scholar 

  • Wright EF. Referred craniofacial pain patterns in patients with temporomandibular disorder. J Am Dent Assoc. 2000;131(9):1307–15.

    Article  PubMed  Google Scholar 

  • Yatani H, Komiayama O, Matsuka Y, et al. Systematic review and recommendations for nonodontogenic toothache. J Oral Rehabil. 2014;41:843–52.

    Article  PubMed  Google Scholar 

Books and Chapters

  • Sharav Y, Benoliel L. The diagnostic process. In: Orofacial pain & headache. New York: Mosby Elsevier; 2008. p. 1–17.

    Chapter  Google Scholar 

  • Simons DG, Travell JG, Simons LS. Chapter 2. General overview. In: Travell and Simons’ myofascial pain and dysfunction. The trigger point manual volume 1. Upper half of body. 2nd ed. New York: Lippincot Williams & Wilkins; 1999. p. 11–93.

    Google Scholar 

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Correspondence to Christopher J. Spencer ODS .

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Spencer, C.J. (2017). The Examination, Differential Diagnosis, and Management of Toothache Pain. In: Weinstein, G., Zientz, M. (eds) The Dental Reference Manual. Springer, Cham. https://doi.org/10.1007/978-3-319-39730-6_19

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  • DOI: https://doi.org/10.1007/978-3-319-39730-6_19

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