Skip to main content

Review of Automatic Segmentation Methods of White Matter Lesions on MRI Data

  • Conference paper
  • First Online:
Innovation in Medicine and Healthcare 2016 (InMed 2016)

Part of the book series: Smart Innovation, Systems and Technologies ((SIST,volume 60))

Included in the following conference series:

Abstract

White matter (WM) lesions are a phenomena perceived in magnetic resonance imaging (MRI) which is prevalent in many different brain pathologies, hence the general interest in automated methods for lesion segmentation (LS). We provide a short review of some commonly used state-of-the-art approaches. The article is focused on the machine learning techniques which researches use to construct semi- and fully-automated tools for LS. In addition, we mention the preprocessing steps, features extraction, LS databases and validation techniques.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Anbeek, P., Vincken, K.L., van Osch, M.J.P., Bisschops, R.H.C., van der Grond, J.: Automatic segmentation of different-sized white matter lesions by voxel probability estimation. Med. Image Anal. 8(3), 205–215 (2004) (Medical Image Computing and Computer-Assisted Intervention—MICCAI 2003)

    Google Scholar 

  2. Anbeek, P., Vincken, K.L., van Osch, M.J.P., Bisschops, R.H.C., van der Grond, J.: Probabilistic segmentation of white matter lesions in mri imaging. NeuroImage 21(3), 1037–1044 (2004)

    Google Scholar 

  3. Bijar, A., Khayati, R., Penalver-Benavent, A.: Increasing the contrast of the brain mr flair images using fuzzy membership functions and structural similarity indices in order to segment ms lesions. PLoS ONE 8(6), e65469 (2013)

    Google Scholar 

  4. de Boer, R., Vrooman, H.A., van der Lijn, F., Vernooij, M.W., Arfan Ikram, M., van der Lugt, A., Breteler, M.M.B., Niessen, W.J.: White matter lesion extension to automatic brain tissue segmentation on mri. NeuroImage 45(4), 1151–1161 (2009)

    Google Scholar 

  5. Garcia-Lorenzo, D., Francis, S., Narayanan, S., Arnold, D.L., Collins, D.L.: Review of automatic segmentation methods of multiple sclerosis white matter lesions on conventional magnetic resonance imaging. Med. Image Anal. 17(1), 1–18 (2013)

    Google Scholar 

  6. Jain, S., Sima, D.M., Ribbens, A., Cambron, M., Maertens, A., Van Hecke, W., De Mey, J., Barkhof, F., Steenwijk, M.D., Daams, M., Maes, F., Van Huffel, S., Vrenken, H., Smeets, D.: Automatic segmentation and volumetry of multiple sclerosis brain lesions from MR images. NeuroImage: Clinical 8, 367–375 (2015)

    Google Scholar 

  7. Klöppel, S., Abdulkadir, A., Hadjidemetriou, S., Issleib, S., Frings, L., Thanh, T., Mader, I., Teipel, S., Hüll, M., Ronneberger, O.: A comparison of different automated methods for the detection of white matter lesions in MRI data. NeuroImage 57(2), 416–422 (2011)

    Article  Google Scholar 

  8. Mitra, J., Bourgeat, P., Fripp, J., Ghose, S., Rose, S., Salvado, O., Connelly, A., Campbell, B., Palmer, S., Sharma, G., Christensen, Soren, Carey, L.: Lesion segmentation from multimodal MRI using random forest following ischemic stroke. NeuroImage 98, 324–335 (2014)

    Article  Google Scholar 

  9. Ramirez, J., Gibson, E., Quddus, A., Lobaugh, N.J., Feinstein, A., Levine, B., Scott, C.J.M., Levy-Cooperman, N., Gao, F.Q., Black, S.E.: Lesion explorer: a comprehensive segmentation and parcellation package to obtain regional volumetrics for subcortical hyperintensities and intracranial tissue. NeuroImage 54(2), 963–973 (2011)

    Article  Google Scholar 

  10. Roy, P.K., Bhuiyan, A., Janke, A., Desmond, P.M., Wong, T.Y., Abhayaratna, W.P., Storey, E., Ramamohanarao, K.: Automatic white matter lesion segmentation using contrast enhanced flair intensity and markov random field. Comput. Med. Imaging Graph. 45, 102–111 (2015)

    Google Scholar 

  11. Schmidt, P., Gaser, C., Arsic, M., Buck, D., Forschler, A., Berthele, A., Hoshi, M., Ilg, R., Schmid, V.J., Zimmer, C., Hemmer, B., Muhlau, M.: An automated tool for detection of flair-hyperintense white-matter lesions in multiple sclerosis. NeuroImage 59(4), 3774–3783 (2012)

    Article  Google Scholar 

  12. Seghier, M.L., Ramlackhansingh, A., Crinion, J., Leff, A.P., Price, C.J.: Lesion identification using unified segmentation-normalisation models and fuzzy clustering. NeuroImage 41(4), 1253–1266 (2008)

    Article  Google Scholar 

  13. Steenwijk, M.D., Pouwels, P.J.W., Daams, M., van Dalen, J.W., Caan, M.W.A., Richard, E., Barkhof, F., Vrenken, H.: Accurate white matter lesion segmentation by k nearest neighbor classification with tissue type priors (knn-ttps). NeuroImage: Clinical 3, 462–469 (2013)

    Google Scholar 

  14. Sweeney, E.M., Vogelstein, J.T., Cuzzocreo, J.L., Calabresi, P.A., Reich, D.S., Crainiceanu, C.M., Shinohara, R.T.: A comparison of supervised machine learning algorithms and feature vectors for ms lesion segmentation using multimodal structural mri. PLoS ONE 9(4), e95753 (2014)

    Google Scholar 

  15. Valverde, S., Oliver, A., Roura, E., Pareto, D., Vilanova, J.C., Ramio-Torrenta, L., Sastre-Garriga, J., Montalban, X., Rovira, A., Llado, X.: Quantifying brain tissue volume in multiple sclerosis with automated lesion segmentation and filling. NeuroImage: Clinical (2015)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Manuel Graña .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this paper

Cite this paper

Chyzhyk, D., Graña, M., Ritter, G. (2016). Review of Automatic Segmentation Methods of White Matter Lesions on MRI Data. In: Chen, YW., Tanaka, S., Howlett, R., Jain, L. (eds) Innovation in Medicine and Healthcare 2016. InMed 2016. Smart Innovation, Systems and Technologies, vol 60. Springer, Cham. https://doi.org/10.1007/978-3-319-39687-3_29

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-39687-3_29

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-39686-6

  • Online ISBN: 978-3-319-39687-3

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics