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Strategies for the Gene Modification of Megakaryopoiesis and Platelets

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Molecular and Cellular Biology of Platelet Formation

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Abstract

Platelets are the central players controlling blood hemostasis. Deregulation of their function leads to various bleeding disorders in human patients with sometimes life-threatening symptoms. To develop therapeutic approaches for these patients, we have to understand the mechanisms behind the diseases.

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Authors and Affiliations

  1. Research Group for Gene Modification in Stem Cells, LOEWE Centre for Cell and Gene Therapy Frankfurt, Paul-Ehrlich-Institute, Langen, Germany

    Lisette Johana Latorre Rey & Ute Modlich

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  1. Lisette Johana Latorre Rey
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  2. Ute Modlich
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Correspondence to Lisette Johana Latorre Rey .

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Editors and Affiliations

  1. Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany

    Harald Schulze

  2. Vascular Biology Programm, Harvard Medical School, Boston, Massachusetts, USA

    Joseph Italiano

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Rey, L.J.L., Modlich, U. (2016). Strategies for the Gene Modification of Megakaryopoiesis and Platelets. In: Schulze, H., Italiano, J. (eds) Molecular and Cellular Biology of Platelet Formation. Springer, Cham. https://doi.org/10.1007/978-3-319-39562-3_20

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