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Diagnosis of Inherited and Acquired Platelet Disorders

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Molecular and Cellular Biology of Platelet Formation

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Abstract

In this chapter we will focus on current laboratory methods to identify platelet function tests to identify the underlying (genetic) defect, allowing to apply the best possible treatment options. There are many reviews written on platelet function assays, especially on drug-induced defects or on drug monitoring, as used in many point-of-care applications [1–3]. Here, we will focus less on the methods underlying the distinct platelet function assays, but rather discuss methods to identify inherited thrombocytopathies.

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Authors and Affiliations

  1. Center for Clinical Transfusion Medicine, Tübingen, Germany

    Tamam Bakchoul

  2. Experimental Biomedicine, University Hospital Würzburg, Josef-Schneider-Str. 2, D15, Würzburg, 97080, Germany

    Harald Schulze

Authors
  1. Tamam Bakchoul
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  2. Harald Schulze
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Correspondence to Harald Schulze .

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Editors and Affiliations

  1. Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany

    Harald Schulze

  2. Vascular Biology Programm, Harvard Medical School, Boston, Massachusetts, USA

    Joseph Italiano

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Bakchoul, T., Schulze, H. (2016). Diagnosis of Inherited and Acquired Platelet Disorders. In: Schulze, H., Italiano, J. (eds) Molecular and Cellular Biology of Platelet Formation. Springer, Cham. https://doi.org/10.1007/978-3-319-39562-3_17

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