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Personalized Medicine in Gastroenterology

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Personalized Medicine

Part of the book series: Europeanization and Globalization ((EAG,volume 2))

Abstract

Personalized medicine systematically uses all available information about a patient, including his/her molecular make-up, in order to optimize preventive, diagnostic, and/or therapeutic measures. In gastroenterology, it is mainly applied for managing inflammatory bowel diseases (therapeutic approach, drug toxicity), gastrointestinal malignancies (development of biomarkers of early recognition, therapy optimization), viral hepatitis (markers of response to therapy, optimization of therapy), H. pylori associated diseases (virulency, tendency to develop certain complications, response to therapy), and many other diseases. Despite the anticipated financial and ethical obstacles, personalized medicine offers the possibility of more precise diagnostics, more accurate therapy, and better prevention, which will in turn result in better long-term treatment outcomes.

Professor Davor Štimac, M.D., Ph.D., Head of KBC Rijeka, Division of Gastroenterology, Department of Internal medicine, University Hospital Rijeka, Rijeka, Croatia.

 Neven Franjić, M.D., Ph.D., Division of Gastroenterology, Department of Internal medicine, University Hospital Rijeka, Rijeka, Croatia.

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Notes

  1. 1.

    Guttmacher and Collins (2002) Zavod za javno zdravstvo “dr. Andrija Štampar”, Personalizirana medicina. Available at: http://www.stampar.hr/Default.aspx?art=2229&sec=16.

  2. 2.

    Hamburg and Collins (2010).

  3. 3.

    Issa (2007).

  4. 4.

    Gill et al. (2006).

  5. 5.

    Patel and Babyatsky (2008).

  6. 6.

    Barrett et al. (2008), Somma et al. (2013), Tešija Kuna (2013), and Mendoza and Abreu (2009).

  7. 7.

    Patel and Babyatsky (2008).

  8. 8.

    Weinshilboum and Sladek (1980).

  9. 9.

    Coenen et al. (2014).

  10. 10.

    Panaccione and Ghosh (2010).

  11. 11.

    Markowitz and Bertagnolli (2009).

  12. 12.

    Patel and Babyatsky (2008).

  13. 13.

    Lynch et al. (2010) and Chao (2012).

  14. 14.

    Ramchandani et al. (2007).

  15. 15.

    Yen and McLeod (2007).

  16. 16.

    Saito and Camilleri (2006).

  17. 17.

    Ge et al. (2009).

  18. 18.

    Morrow et al. (2009).

  19. 19.

    European Association for the Study of the Liver (2014).

  20. 20.

    Miki et al. (2012).

  21. 21.

    Wen et al. (2007) and Dossumbekova et al. (2006).

  22. 22.

    Malfertheiner et al. (2012).

  23. 23.

    Chong and Ensom (2003) and Hagymasi et al. (2011).

  24. 24.

    Ozawa et al. (2004) and Hunfeld et al. (2008).

  25. 25.

    D’Haens et al. (2008).

  26. 26.

    Dignass et al. (2010).

  27. 27.

    Bouvier et al. (2010).

  28. 28.

    Schmalfuss and Kolominsky-Rabas (2013).

  29. 29.

    Guttmacher and Collins (2002); Zavod za javno zdravstvo “dr. Andrija Štampar”, Personalizirana medicina. Available at: http://www.stampar.hr/Default.aspx?art=2229&sec=16.

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Author information

Authors and Affiliations

  1. Division of Gastroenterology, Department of Internal Medicine, University Hospital Rijeka, Rijeka, Croatia

    Davor Štimac M.D., Ph.D. & Neven Franjić M.D., Ph.D.

Authors
  1. Davor Štimac M.D., Ph.D.
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  2. Neven Franjić M.D., Ph.D.
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Corresponding author

Correspondence to Davor Štimac M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Jean Monnet Department of European Public Law, University of Rijeka, Rijeka, Croatia

    Nada Bodiroga-Vukobrat

  2. Croatian Academy of Sciences and Arts, Rijeka, Croatia

    Daniel Rukavina

  3. Department of Biotechnology, University of Rijeka , Rijeka, Croatia

    Krešimir Pavelić

  4. University of Applied Sciences, Hochschule für öffentliche Verwaltung und Finanzen Ludwigsburg, Ludwigsburg, Germany

    Gerald G. Sander

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Štimac, D., Franjić, N. (2016). Personalized Medicine in Gastroenterology. In: Bodiroga-Vukobrat, N., Rukavina, D., Pavelić, K., Sander, G. (eds) Personalized Medicine. Europeanization and Globalization, vol 2. Springer, Cham. https://doi.org/10.1007/978-3-319-39349-0_13

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  • DOI: https://doi.org/10.1007/978-3-319-39349-0_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-39347-6

  • Online ISBN: 978-3-319-39349-0

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