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Personalized Medicine: The Path to New Medicine

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Personalized Medicine

Part of the book series: Europeanization and Globalization ((EAG,volume 2))

Abstract

Personalised medicine is a new paradigm that represents a shift from current simplified consideration of the patient as a member of the population sharing common fate of disease towards the view that each patient is a unique individual. Every person has specific genomic/proteomic and metabolic signature that could account for specific clinical features of disease, response to treatment and disease severity. Therefore, disease and the treatment itself should be considered individually. Due to a number of reasons for introduction of new paradigm in medicine, implementation of personalised medicine is envisaged in several consecutive steps where projections of the levels of technology, medicine and integration need to be coordinated.

Professor Krešimir Pavelić, M.D. Ph.D., Head of Laboratory for High-Throughput Analytics, University Centre for High-Throughput Technologies, Department of Biotechnology, University of Rijeka, Rijeka, Croatia.

 Professor Sandra Kraljević Pavelić, Ph.D., University Centre for High-Throughput Technologies, Department of Biotechnology, University of Rijeka, Rijeka, Croatia.

 Assistant Professor Mirela Sedić, Ph.D., University Centre for High-Throughput Technologies, Department of Biotechnology, University of Rijeka, Rijeka, Croatia.

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Notes

  1. 1.

    Pavelić et al. (2015).

  2. 2.

    Bošnjak et al. (2008) and Kralj and Pavelić (2003).

  3. 3.

    Catchpoole et al. (2010).

  4. 4.

    Bošnjak et al. (2008), Kraljevic et al. (2006), and Van’t Veer and Bernards (2008).

  5. 5.

    ESF Forward Look (2012).

  6. 6.

    Aspinall and Hamermesh (2007).

  7. 7.

    Goldstein et al. (2003).

  8. 8.

    Aspinall and Hamermesh (2007), Goldstein et al. (2003), and Van't Veer and Bernards (2008).

  9. 9.

    Clark et al. (2006).

  10. 10.

    ESF Forward Look (2012), Bošnjak et al. (2008), Petricoin et al. (2002), and Li et al. (2008).

  11. 11.

    Pavelić et al. (2015) and Aspinall and Hamermesh (2007).

  12. 12.

    Petricoin et al. (2002) and Espina et al. (2004).

  13. 13.

    Editorial (2003).

  14. 14.

    ESF Forward Look (2012), Editorial (2003), and Ferrari (2005).

  15. 15.

    Sedić et al. (2014).

  16. 16.

    Walker and Mouton (2006), Pavelić et al. (2015), and Kraljević et al. (2004).

  17. 17.

    Bošnjak et al. (2008) and Kraljević and Pavelić (2005).

  18. 18.

    Pavelić et al. (2014), Catchpoole et al (2010), Subbiah (2007), and European Science Foundation (2005).

  19. 19.

    Astley (2007).

  20. 20.

    Müller and Kersten (2003).

  21. 21.

    Ries and Castle (2008).

  22. 22.

    Aspinall and Hamermesh (2007).

  23. 23.

    Hewitt (2011) and Spaventi et al. (1994).

  24. 24.

    ESF Forward Look (2012).

  25. 25.

    http://www.genome.gov/26525384, accessed on January 1st 2016.

  26. 26.

    Huser et al. (2014).

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Acknowledgements

This text is supported by the Croatian Science Foundation project “5709 – Perspectives of maintaining the social state: towards the transformation of social security systems for individuals in personalized medicine” and University of Rijeka research grants 13.11.1.1.11 and 13.11.1.2.01. We greatly acknowledge the project RISK “Development of University of Rijeka campus laboratory research infrastructure”, financed by European Regional Development Fund (ERDF).

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Authors and Affiliations

  1. Laboratory for High-Throughput Analytics, Department of Biotechnology, University Centre for High-Throughput Technologies, University of Rijeka, Rijeka, Croatia

    Krešimir Pavelić M.D., Ph.D.

  2. Department of Biotechnology, University Centre for High-Throughput Technologies, University of Rijeka, Rijeka, Croatia

    Sandra Kraljević Pavelić Ph.D. & Mirela Sedić Ph.D.

Authors
  1. Krešimir Pavelić M.D., Ph.D.
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  2. Sandra Kraljević Pavelić Ph.D.
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  3. Mirela Sedić Ph.D.
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Corresponding author

Correspondence to Krešimir Pavelić M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Jean Monnet Department of European Public Law, University of Rijeka, Rijeka, Croatia

    Nada Bodiroga-Vukobrat

  2. Croatian Academy of Sciences and Arts, Rijeka, Croatia

    Daniel Rukavina

  3. Department of Biotechnology, University of Rijeka , Rijeka, Croatia

    Krešimir Pavelić

  4. University of Applied Sciences, Hochschule für öffentliche Verwaltung und Finanzen Ludwigsburg, Ludwigsburg, Germany

    Gerald G. Sander

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Pavelić, K., Kraljević Pavelić, S., Sedić, M. (2016). Personalized Medicine: The Path to New Medicine. In: Bodiroga-Vukobrat, N., Rukavina, D., Pavelić, K., Sander, G. (eds) Personalized Medicine. Europeanization and Globalization, vol 2. Springer, Cham. https://doi.org/10.1007/978-3-319-39349-0_1

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  • DOI: https://doi.org/10.1007/978-3-319-39349-0_1

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