Abstract
Arteriovenous malformations are abnormal lesions, a tangle (or nidus) of blood vessels connecting directly, which means without capillaries, veins, and arteries in the brain. The redirection of the arterial blood away from brain parenchyma and through the nidus is referred to as a shunt. High blood flow and shunting of high-pressure arterial blood cause the feeder arteries and veins to dilate the nidus and make it vulnerable to bleeding due to ruptures that might happen when these lesions remain untreated.
Invasive surgical procedures and radiologic interventions seem to be the method of choice. Image-guided stereotactic radiosurgery in its multiple technologic appearances as the Linac, Gamma Knife, or CyberKnife radiosurgery could affect in combined regimens the lesion and avoid bleeding, when performed in combination with radiologic interventions and surgery.
Consecutively, it demonstrates a noninvasive high-precision and safe technique in treating patients (f/m) with traceable improvement of quality of life. Image-guided stereotactic radiosurgery is cost-efficient.
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References
Ding D, Starke RM, Kano H, Mathieu D, Huang P, Kondziolka D, et al. Radiosurgery for cerebral arteriovenous malformations in a randomized trial of unruptured brain arteriovenous malformations (ARUBA)-eligible patients: a multicenter study. Stroke. 2016;47(2):342–9.
Oermann EK, Rubinsteyn A, Ding D, Mascitelli J, Starke RM, Bederson JB, et al. Using a machine learning approach to predict outcomes after radiosurgery for cerebral arteriovenous malformations. Sci Rep. 2016;6:21161.
Ogilvy CS, Stieg PE, Awad I, Brown Jr RD, Kondziolka D, Rosenwasser R, et al. Recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association. Circulation. 2001;103(21):2644–57.
Ogilvy CS, Stieg PE, Awad I, Brown Jr RD, Kondziolka D, Rosenwasser R, et al. AHA Scientific Statement: recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association. Stroke. 2001;32(6):1458–71.
Mohr JP, Parides MK, Stapf C, Moquete E, Moy CS, Overbey JR, et al. Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial. Lancet. 2014;383(9917):614–21.
Mohr JP. Results of ARUBA are applicable to most patients with nonruptured arteriovenous malformations. Stroke. 2014;45(5):1541–2.
van Beijnum J, van der Worp HB, Buis DR, Al-Shahi Salman R, Kappelle LJ, Rinkel GJ, et al. Treatment of brain arteriovenous malformations: a systematic review and meta-analysis. JAMA. 2011;306(18):2011–9.
Moorthy RK, Rajshekhar V. Stereotactic radiosurgery for intracranial arteriovenous malformations: a review. Neurol India. 2015;63(6):841–51.
Mau CY, Sabourin VM, Gandhi CD, Prestigiacomo CJ. SLAM: stereotactic radiosurgery of large arteriovenous malformations: meta-analysis of hemorrhage in high-grade Pollock-Flickinger arteriovenous malformations. World Neurosurg. 2015.
Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, et al. Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm. J Neurosurg. 2016;124(1):163–74.
Ding D, Xu Z, Shih HH, Starke RM, Yen CP, Sheehan JP. Stereotactic radiosurgery for partially resected cerebral arteriovenous malformations. World Neurosurg. 2016;85:263–72.
Cohen-Inbar O, Ding D, Sheehan JP. Stereotactic radiosurgery for deep intracranial arteriovenous malformations, part 2: Basal ganglia and thalamus arteriovenous malformations. J Clin Neurosci. 2016;24:37–42.
Cohen-Inbar O, Ding D, Chen CJ, Sheehan JP. Stereotactic radiosurgery for deep intracranial arteriovenous malformations, part 1: Brainstem arteriovenous malformations. J Clin Neurosci. 2016;24:30–6.
Zeiler FA, Janik MK, McDonald PJ, Kaufmann AM, Fewer D, Butler J, et al. Gamma Knife radiosurgery for pediatric arteriovenous malformations: a Canadian experience. Can J Neurol Sci. 2015;1–5.
Shin SS, Murdoch G, Hamilton RL, Faraji AH, Kano H, Zwagerman NT, et al. Pathological response of cavernous malformations following radiosurgery. J Neurosurg. 2015;123(4):938–44.
Sheehan J, Ding D, Starke RM. Radiosurgery and cavernous malformations. J Neurosurg. 2015;123(4):935–6.
Mariashev SA, Golanov AV, Konovalov AN, Gorlachev GE, Iakovlev SB, Dalechina AV, et al. The outcomes of stereotactic radiotherapy in patients with cerebral arteriovenous malformations. Zh Vopr Neirokhir Im N N Burdenko. 2015;79(1):14–32.
Lindvall P, Grayson D, Bergstrom P, Bergenheim AT. Hypofractionated stereotactic radiotherapy in medium-sized to large arteriovenous malformations. J Clin Neurosci. 2015;22(6):955–8.
Lee SH, Lim YJ. Stereotactic radiosurgery for cavernous malformations: prejudice from ignorance. Acta Neurochir. 2015;157(1):51–2.
Lee CC, Chen CJ, Ball B, Schlesinger D, Xu Z, Yen CP, et al. Stereotactic radiosurgery for arteriovenous malformations after Onyx embolization: a case–control study. J Neurosurg. 2015;123(1):126–35.
Kida Y, Hasegawa T, Iwai Y, Shuto T, Satoh M, Kondoh T, et al. Radiosurgery for symptomatic cavernous malformations: a multi-institutional retrospective study in Japan. Surg Neurol Int. 2015;6 Suppl 5:S249–57.
Jung H, Shah A. Factors determining obliteration in intracranial arteriovenous malformations and associated complications with stereotactic radiosurgery. Clin Neurol Neurosurg. 2015;136:71–2.
Jabbour P, Daou B, Andrews D. Stereotactic radiosurgery for arteriovenous malformations with radiosurgery-based arteriovenous malformation score <1. World Neurosurg. 2015;83(4):488–9.
Hanakita S, Shin M, Koga T, Igaki H, Saito N. Outcomes of volume-staged radiosurgery for cerebral arteriovenous malformations larger than 20cm3 with more than 3 years of follow-up. World Neurosurg. 2015.
Hanakita S, Koga T, Shin M, Igaki H, Saito N. The long-term outcomes of radiosurgery for arteriovenous malformations in pediatric and adolescent populations. J Neurosurg Pediatr. 2015;16(2):222–31.
Galvan De la Cruz OO, Ballesteros-Zebadua P, Moreno-Jimenez S, Celis MA, Garcia-Garduno OA. Stereotactic radiosurgery for pediatric patients with intracranial arteriovenous malformations: variables that may affect obliteration time and probability. Clin Neurol Neurosurg. 2015;129:62–6.
Ding D, Xu Z, Yen CP, Starke RM, Sheehan JP. Radiosurgery for unruptured cerebral arteriovenous malformations in pediatric patients. Acta Neurochir. 2015;157(2):281–91.
Ding D, Xu Z, Yen CP, Starke RM, Sheehan JP. Radiosurgery for cerebral arteriovenous malformations in elderly patients: effect of advanced age on outcomes after intervention. World Neurosurg. 2015;84(3):795–804.
Ding D, Starke RM, Kano H, Mathieu D, Huang P, Kondziolka D, et al. Radiosurgery for cerebral arteriovenous malformations in a randomized trial of unruptured brain arteriovenous malformations (ARUBA)-eligible patients: a multicenter study. Stroke. 2015.
Ding D, Sheehan JP, Starke RM, Durst CR, Raper DM, Conger JR, et al. Embolization of cerebral arteriovenous malformations with silk suture particles prior to stereotactic radiosurgery. J Clin Neurosci. 2015;22(10):1643–9.
Ding D, Quigg M, Starke RM, Xu Z, Yen CP, Przybylowski CJ, et al. Radiosurgery for temporal lobe arteriovenous malformations: effect of temporal location on seizure outcomes. J Neurosurg. 2015;123(4):924–34.
Ding D. Predicting outcomes from radiosurgery for intracranial arteriovenous malformations: effect of embolization, prior hemorrhage, and nidus anatomy. Neurol Sci. 2015;36(6):1025–6.
Ding D. Effect of stereotactic radiosurgery on the hemorrhage risk of cerebral cavernous malformations: fact or fiction? Acta Neurochir. 2015;157(1):49–50.
Chytka T, Liscak R, Kozubikova P, Vymazal J. Radiosurgery for large arteriovenous malformations as a single-session or staged treatment. Stereotact Funct Neurosurg. 2015;93(5):342–7.
Xu F, Zhong J, Ray A, Manjila S, Bambakidis NC. Stereotactic radiosurgery with and without embolization for intracranial arteriovenous malformations: a systematic review and meta-analysis. Neurosurg Focus. 2014;37(3), E16.
Baranoski JF, Grant RA, Hirsch LJ, Visintainer P, Gerrard JL, Gunel M, et al. Seizure control for intracranial arteriovenous malformations is directly related to treatment modality: a meta-analysis. J Neurointerv Surg. 2014;6(9):684–90.
Gross BA, Du R. Natural history of cerebral arteriovenous malformations: a meta-analysis. J Neurosurg. 2013;118(2):437–43.
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Badakhshi, H. (2016). Arteriovenous Malformations of the Central Nervous System. In: Image-Guided Stereotactic Radiosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-39189-2_8
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DOI: https://doi.org/10.1007/978-3-319-39189-2_8
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