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Hepatocellular Carcinoma pp 531–546Cite as

Radiation Therapy for Hepatocellular Carcinoma

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Part of the book series: Current Clinical Oncology ((CCO))

Abstract

There are many factors that have over time, contributed to the limited use of ionizing radiation in treating hepatocellular carcinoma. Primarily, it is due to the fact that delivery of tumorcidal doses of radiation to a tumor will exceed tolerance of the normal surrounding liver. X-rays produce nondiscriminatory cell killing in the already diseased liver of HCC patients. In the past, radiation beams could only be delivered in the simplest of geometric arrangements, which could not avoid enough normal liver tissue from X-rays to deliver doses of radiation to control solid tumors. Only in the past 15 years technological advancements in Radiation Oncology and Diagnostic Radiology allowed for innovative approaches in both external beam and brachytherapy for treatment of liver malignancies.

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Authors and Affiliations

  1. Radiation Oncology Research, Sarah Cannon Research Institute, Nashville, TN, USA

    Andrew S. Kennedy

  2. Department of Biomedical Engineering, North Carolina State University, Raleigh, NC, USA

    Andrew S. Kennedy

  3. Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC, USA

    Andrew S. Kennedy

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  1. Andrew S. Kennedy
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Correspondence to Andrew S. Kennedy .

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  1. Dokuz Eylul University, Izmir Biomedicine and Genome Center Dokuz Eylul University, Izmir, Izmir, Turkey

    Brian I. Carr

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© 2016 Springer International Publishing Switzerland

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Kennedy, A.S. (2016). Radiation Therapy for Hepatocellular Carcinoma. In: Carr, B. (eds) Hepatocellular Carcinoma. Current Clinical Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-34214-6_35

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  • DOI: https://doi.org/10.1007/978-3-319-34214-6_35

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