Abstract
Alzheimer’s disease has probably existed since mammals roamed the earth although it was not recognized as a disease until 1907. In that year, Alois Alzheimer, a German neuropathologist, published his landmark paper describing a mentally ill patient whose brain after death showed strange deposits later described as senile plaques and neurofibrillary tangles. These microbodies are now known to be the hallmarks of Alzheimer’s disease although they are also found in other dementing disorders such as vascular dementia and dementia pugilistica, also known as “punch-drunk syndrome,” so-called because it was first discovered in boxers who had sustained repeated blows to the head.
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de la Torre, J.C. (2016). Alzheimer’s Then and Now. In: Alzheimer’s Turning Point. Springer, Cham. https://doi.org/10.1007/978-3-319-34057-9_4
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DOI: https://doi.org/10.1007/978-3-319-34057-9_4
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