Abstract
Shockwave treatments are commonly used in the management of tendon injuries and there is increasing evidence for its clinical effectiveness. There is a paucity of fundamental (in vivo) studies investigating the biological action of shockwave therapy. Destruction of calcifications, pain relief and mechanotransduction-initiated tissue regeneration and remodeling of the tendon are considered to be the most important working mechanisms. The heterogeneity of systems (focussed shockwave therapy vs. radial pressurewave therapy), treatment protocols and study populations, and the fact that there seem to be responders and non-responders, continue to make it difficult to give firm recommendations with regard to the most optimal shockwave therapy approach. Specific knowledge with regard to the effects of shockwave therapy in patients with metabolic tendon disorders is not available. Further fundamental and clinical research is required to determine the value of shockwave therapy in the management of tendinopathy.
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Abbreviations
- CGRP:
-
calcitonin gene-related peptide
- EFD:
-
energy flux density
- EH:
-
electrohydraulic
- EM:
-
electromagnetic
- F-SWT:
-
focused shockwave therapy
- IL:
-
interleukin
- MMP:
-
matrix metalloproteases
- PE:
-
piezoelectric
- R-PWT:
-
radial pressure wave therapy
- SWT:
-
shockwave therapy
- TGF-β1:
-
transforming growth factor β1
References
Huisstede BM, Gebremariam L, van der Sande R, Hay EM, Koes BW (2011) Evidence for effectiveness of Extracorporal Shock-Wave Therapy (ESWT) to treat calcific and non-calcific rotator cuff tendinosis – a systematic review. Man Ther 16(5):419–433
Ioppolo F, Tattoli M, Di Sante L, Venditto T, Tognolo L, Delicata M et al (2013) Clinical improvement and resorption of calcifications in calcific tendinitis of the shoulder after shock wave therapy at 6 months’ follow-up: a systematic review and meta-analysis. Arch Phys Med Rehabil 94(9):1699–1706
Speed C (2014) A systematic review of shockwave therapies in soft tissue conditions: focusing on the evidence. Br J Sports Med 48(21):1538–1542
Mani-Babu S, Morrissey D, Waugh C, Screen H, Barton C (2015) The effectiveness of extracorporeal shock wave therapy in lower limb tendinopathy: a systematic review. Am J Sports Med 43(3):752–761
Yin MC, Ye J, Yao M, Cui XJ, Xia Y, Shen QX et al (2014) Is extracorporeal shock wave therapy clinical efficacy for relief of chronic, recalcitrant plantar fasciitis? A systematic review and meta-analysis of randomized placebo or active-treatment controlled trials. Arch Phys Med Rehabil 95(8):1585–1593
van der Worp H, van den Akker-Scheek I, van Schie H, Zwerver J (2013) ESWT for tendinopathy: technology and clinical implications. Knee Surg Sports Traumatol Arthrosc 21(6):1451–1458
Waugh CMCM (2015) In vivo biological response to extracorporeal shockwave therapy in human tendinopathy. Eur Cell Mater 29:268–280
Gerdesmeyer L, Maier M, Haake M, Schmitz C (2002) Physical-technical principles of extracorporeal shockwave therapy (ESWT). Orthopade 31(7):610–617
Cleveland RO, Chitnis PV, McClure SR (2008) Shock wave therapy: what really matters reply. Ultrasound Med Biol 34(11):1869–1870
Cleveland RO, Chitnis PV, McClure SR (2007) Acoustic field of a ballistic shock wave therapy device. Ultrasound Med Biol 33(8):1327–1335
Lohrer H, Nauck T, Dorn-Lange NV, Scholl J, Vester JC (2010) Comparison of radial versus focused extracorporeal shock waves in plantar fasciitis using functional measures. Foot Ankle Int 31(1):1–9
van der Worp H, Zwerver J, Hamstra M, van den Akker-Scheek I, Diercks RL (2014) No difference in effectiveness between focused and radial shockwave therapy for treating patellar tendinopathy: a randomized controlled trial. Knee Surg Sports Traumatol Arthrosc 22(9):2026–2032
Mariotto S, Cavalieri E, Amelio E, Ciampa AR, de Prati AC, Marlinghaus E et al (2005) Extracorporeal shock waves: from lithotripsy to anti-inflammatory action by NO production. Nitric Oxide 12(2):89–96
Rompe JD, Krischek O, Eysel P, Hopf C, Jage J (1998) Results of extracorporeal shock-wave application in lateral elbow tendopathy. Schmerz 12(2):105–111
Wess OJ (2008) A neural model for chronic pain and pain relief by extracorporeal shock wave treatment. Urol Res 36(6):327–334
Rio E, Moseley L, Purdam C, Samiric T, Kidgell D, Pearce AJ et al (2014) The pain of tendinopathy: physiological or pathophysiological? Sports Med 44(1):9–23
Maier M, Averbeck B, Milz S, Refior H, Schmitz C (2003) Substance P and prostaglandin E-2 release after shock wave application to the rabbit femur. Clin Orthop 1(406):237–245
Hausdorf J, Lemmens MA, Kaplan S, Marangoz C, Milz S, Odaci E et al (2008) Extracorporeal shockwave application to the distal femur of rabbits diminishes the number of neurons immunoreactive for substance P in dorsal root ganglia L5. Brain Res 1207(1):96–101
Takahashi N, Wada Y, Ohtori S, Saisu T, Moriya H (2003) Application of shock waves to rat skin decreases calcitonin gene-related peptide immunoreactivity in dorsal root ganglion neurons. Auton Neurosci Basic Clin 107(2):81–84
Hausdorf J, Lemmens MA, Heck KD, Grolms N, Korr H, Kertschanska S et al (2008) Selective loss of unmyelinated nerve fibers after extracorporeal shockwave application to the musculoskeletal system. Neuroscience 155(1):138–144
Schmitz C, DePace R (2009) Pain relief by extracorporeal shockwave therapy: an update on the current understanding. Urol Res 37(4):231–234
Khan KM, Scott A (2009) Mechanotherapy: how physical therapists’ prescription of exercise promotes tissue repair. Br J Sports Med 43(4):247–252
Chen Yeung-Jen YJ (2004–7) Extracorporeal shock waves promote healing of collagenase-induced Achilles tendinitis and increase TGF-beta1 and IGF-I expression. J Orthop Res 22(4):854–861
Wang Ching-Jen CJ (2003–11) Shock wave therapy induces neovascularization at the tendon-bone junction. A study in rabbits. J Orthop Res 21(6):984–989
Vetrano Mario M (2011–12) Extracorporeal shock wave therapy promotes cell proliferation and collagen synthesis of primary cultured human tenocytes. Knee Surg Sports Traumatol Arthrosc 19(12):2159–2168
Bosch GG (2009–4) The effect of focused extracorporeal shock wave therapy on collagen matrix and gene expression in normal tendons and ligaments. Equine Vet J 41(4):335–341
Bosch GG (2007–5) Effect of extracorporeal shock wave therapy on the biochemical composition and metabolic activity of tenocytes in normal tendinous structures in ponies. Equine Vet J 39(3):226–231
Han SH, Lee JW, Guyton GP, Parks BG, Courneya J, Schon LC (2009) Effect of extracorporeal shock wave therapy on cultured tenocytes. Foot Ankle Int 30(2):93–98
Waugh CM, Morrissey D, Jones E, Riley GP, Langberg H, Screen HR (2015) In vivo biological response to extracorporeal shockwave therapy in human tendinopathy. Eur Cell Mater 29:268–280; discussion 280
Mani-Babu S, Waugh CM, Screen HR, Maffulli N, Morrissey D (2013) The effects of extracorporeal shock wave therapy (ESWT) on type I collagen synthesis in the Achilles tendon: an intervention study on healthy participants. Int J Exp Pathol 94:A11–A12
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Glossary
- Energy flux density, (EFD, in mJ/mm2)
-
a term used to reflect the flow of shockwave energy in an area perpendicular to the direction of propagation. Shockwave dosage is broadly divided in high (EFD > 0.12 mJ/mm2) and low (EFD ≤ 0.12 mJ/mm2) energy delivery.
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Zwerver, J., Waugh, C., van der Worp, H., Scott, A. (2016). Can Shockwave Therapy Improve Tendon Metabolism?. In: Ackermann, P., Hart, D. (eds) Metabolic Influences on Risk for Tendon Disorders. Advances in Experimental Medicine and Biology, vol 920. Springer, Cham. https://doi.org/10.1007/978-3-319-33943-6_26
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DOI: https://doi.org/10.1007/978-3-319-33943-6_26
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