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Electrical Fluctuations on the Surfaces of Proteins from Hydrodynamic Data

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Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Abstract

We calculate the electrical capacitance on the surface of protein molecules from hydrodynamic data of the proteins. Then, we estimate the electrical fluctuations (charge, voltage) through the fluctuation-dissipation theorem which links the electrical capacitance of the system with these fluctuations. From the intrinsic viscosity of the proteins we estimate the polarizability which leads to the knowledge of the field and dipole fluctuations. From the fitting of the capacitance, polarizability and electrical fluctuations as a function of the molecular weight of the proteins we report numerical equations which allow to estimate these physical magnitudes for a given protein knowing the molecular weight. Charge fluctuations are in the fraction of unit charge range, voltage fluctuations are in the three mV digit range, field fluctuations are in the two digit mV/nm (106 V/m) range and the dipole moment fluctuations range from the two to three digit times the dipole moment of water molecule. These surface properties of proteins have not been reported before.

Keywords

Proteins electrical fluctuations Proteins dipole fluctuations Proteins field fluctuations Proteins voltage fluctuations 

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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  1. 1.Federal University of GoiásGoiâniaBrazil

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