Skip to main content
SpringerLink
Log in

Inflammatory Bowel Disease

  • Chapter
  • First Online:
Pocket Handbook of GI Pharmacotherapeutics

Part of the book series: Clinical Gastroenterology ((CG))

  • 892 Accesses

Abstract

Crohn’s disease and ulcerative colitis are the two major forms of idiopathic inflammatory bowel diseases. Crohn’s disease is a condition of chronic transmural inflammation which may potentially involve any location of the alimentary tract. Ulcerative colitis is a chronic idiopathic inflammatory condition affecting the large bowel. This chapter reviews the recommended treatments for these conditions.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Van Assche G, Dignass A, Panes J, Beaugerie L, Karagiannis J, Allez M, Ochsenkühn T, Orchard T, Rogler G, Louis E, Kupcinskas L, Mantzaris G, Travis S, Stange E. The second European evidence-based consensus on the diagnosis and management of Crohn’s disease: definitions and diagnosis. J Crohn’s Colitis. 2010;4(1):7–27.

    Article  Google Scholar 

  2. Dubinsky MC, Lamothe S, Yang HY, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology. 2000;118:705–13.

    Article  CAS  PubMed  Google Scholar 

  3. Dubinsky MC, Yang H, Hassard PV, Seidman EG, Kam LY, Abreu MT, et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with IBD. Gastroenterology. 2002;122:904–15.

    Article  CAS  PubMed  Google Scholar 

  4. Feldman ML, Sleisenger MH, Fordtran JS, Friedman LS, Brandt LJ. Sleisenger and Fordtran’s gastrointestinal and liver disease: pathophysiology, diagnosis, management. Philadelphia: Saunders/Elsevier; 2010.

    Google Scholar 

  5. Hendy P, Hart A, Irving P. Anti-TNFdrug and antidrug antibody level monitoring in IBD: a practical guide. Frontline Gastroenterol. 2014. doi:10.1136/flgastro-2014-100527.

    Google Scholar 

  6. Kornbluth A, Sachar DB. Ulcerative colitis practice guidelines in adults: American College of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol. 2010;105:501–23.

    Article  PubMed  Google Scholar 

  7. Steenholdt C, Brynskov J, Thomsen OO, Munck LK, et al. Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial. Gut. 2014;63:919–27.

    Article  PubMed  Google Scholar 

  8. UpToDate® 2015

    Google Scholar 

  9. Vaughn BP, Martinez-Vazquez M, Patwardhan VR, et al. Proactive therapeutic concentration monitoring of infliximab may improve outcomes for patients with inflammatory bowel disease: results from a pilot observational study. Inflamm Bowel Dis. 2014;20:1996–2003.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Gastroenterology & Hepatology, University of Connecticut Health Center, 263 Farmington Ave., Farmington, CT, 06030, USA

    Houman Rezaizadeh M.D.

  2. Gastroenterology-Hepatology Fellowship Program, University of Connecticut Health Center, 263 Farmington Ave., Farmington, CT, 06030-1235, USA

    Erik Olson D.O.

Authors
  1. Houman Rezaizadeh M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Erik Olson D.O.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Houman Rezaizadeh M.D. .

Editor information

Editors and Affiliations

  1. Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, Connecticut, USA

    George Y. Wu

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Rezaizadeh, H., Olson, E. (2016). Inflammatory Bowel Disease. In: Wu, G. (eds) Pocket Handbook of GI Pharmacotherapeutics. Clinical Gastroenterology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-33317-5_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-33317-5_5

  • Published:

  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-33315-1

  • Online ISBN: 978-3-319-33317-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation