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Dental Stem Cells and Growth Factors

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Book cover Dental Stem Cells: Regenerative Potential

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

Abstract

The aim of the regenerative medicine and tissue engineering is to regenerate and repair the damaged cells and tissues in order to establish the normal functions [1]. The regenerative medicine involves the use of scaffolds, growth factors and stem cells [2]. Regeneration of the tissues exists naturally due to the presence of stem cells with the potential to self-regenerate and differentiate into one of more specialized cell types [3]. Fundamental to our understanding of regenerative medicine is the knowledge of growth factors that effect on a broad range of cellular activities including migration, proliferation, differentiation and apoptosis of cells, including stem/progenitor cells. Growth factors and cytokines may act as signaling molecules that modulate cell behavior by mediating intracellular communication. The effects of various growth factors on dental stem cells and how they may participate in dental pulp-dentin regeneration will be explained.

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Authors and Affiliations

  1. Centre for Integrative Biology (CIBIO), University of Trento, Trento, Italy

    Paolo Ghensi

  2. Department of Neurosciences, University of Padova, Padova, Italy

    Paolo Ghensi

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  1. Department of Biomedical Sciences, University of Padova, Padova, Italy

    Barbara Zavan

  2. Department of Neurosciences, University of Padova, Padova, Italy

    Eriberto Bressan

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Ghensi, P. (2016). Dental Stem Cells and Growth Factors. In: Zavan, B., Bressan, E. (eds) Dental Stem Cells: Regenerative Potential. Stem Cell Biology and Regenerative Medicine. Humana Press, Cham. https://doi.org/10.1007/978-3-319-33299-4_5

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