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In Patients with Iliofemoral Deep Vein Thrombosis Does Clot Removal Improve Functional Outcome When Compared to Traditional Anticoagulation?

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Difficult Decisions in Vascular Surgery

Part of the book series: Difficult Decisions in Surgery: An Evidence-Based Approach ((DDSURGERY))

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Abstract

Iliofemoral deep vein thrombosis is a common clinical condition which often results in post-thrombotic syndrome, a cause of long-term morbidity due to diminished function. The mainstays of treatment for deep vein thrombosis include anticoagulation and compression therapy but these only prevent propagation of the venous clot. Therapeutic options which actively remove clot decrease the risk of post-thrombotic syndrome when compared to conventional anticoagulation alone, an effect attributed to alleviated obstruction and decreased damage to venous valves. Removal of venous clot with catheter-directed thrombolysis is a safe, effective treatment option which can improve functional outcomes in iliofemoral deep vein thrombosis. In patients with contraindication to thrombolytic therapy, surgical thrombectomy is an alternative which also improves functional outcomes in iliofemoral deep vein thrombosis.

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Authors and Affiliations

  1. Department of Radiology, University of Chicago, Chicago, IL, USA

    Mikin V. Patel MD, MBA & Brian Funaki MD

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  1. Mikin V. Patel MD, MBA
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  2. Brian Funaki MD
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Correspondence to Brian Funaki MD .

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Editors and Affiliations

  1. The University of Chicago Medical Center and Biological Science Division, Chicago, Illinois, USA

    Christopher L. Skelly

  2. The University of Chicago Medical Center and Biological Science Division, Chicago, Illinois, USA

    Ross Milner

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Patel, M.V., Funaki, B. (2017). In Patients with Iliofemoral Deep Vein Thrombosis Does Clot Removal Improve Functional Outcome When Compared to Traditional Anticoagulation?. In: Skelly, C., Milner, R. (eds) Difficult Decisions in Vascular Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer, Cham. https://doi.org/10.1007/978-3-319-33293-2_34

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  • DOI: https://doi.org/10.1007/978-3-319-33293-2_34

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