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Pruritus in Hematological Diseases (Including Aquagenic Pruritus)

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Pruritus

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Abstract

Hematological disorders are malignant neoplasms that derive from myeloid and lymphoid cell lineages. Lymphomas, chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) and others monoclonal gammopathies derived from the lymphoid line while acute and chronic myelogenous leukemia (AML and CML), myelodysplastic syndrome (MDS) and myeloproliferative neosplasms (MPN) are from myeloid origin. A simplified classification is presented in Table 36.2.

Among the numerous symptoms that could be described by patients suffering from hematological malignancies, pruritus is perhaps the most common clinical feature. It is often described as generalized and chronic itch. Recently, pruritus associated with hematological disorders has been defined as paraneoplastic pruritus (Weisshaar et al., Acta Derm Venereol 95(3):261–265, 2015).

This chapter will neither discussed about treatment-induced pruritus described in many cases in hematological malignancies nor about cutaneous T-cell lymphoma (CTCL) and mastocytosis, presented in another chapters (Chap. 22, Mastocytosis, and Chap. 27, Cutaneous Lymphoma, respectively).

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Authors and Affiliations

  1. Laboratory of Neurosciences of Brest, University of Western Brittany, Brest, France

    Christelle Le Gall-Ianotto PhD

  2. Laboratory of Neurosciences of Brest, University Hospital of Brest, Brest, France

    Christelle Le Gall-Ianotto PhD

  3. Laboratory of Neurosciences of Brest, Department of Dermatology, University Hospital, University of Brest, Brest, France

    Laurent Misery MD, PhD

  4. Department of Dermatology and Laboratory of Skin Neurophysiology, University of Western Brittany, Brest, France

    Laurent Misery MD, PhD

Authors
  1. Christelle Le Gall-Ianotto PhD
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  2. Laurent Misery MD, PhD
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Correspondence to Christelle Le Gall-Ianotto PhD .

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Editors and Affiliations

  1. Department of Dermatology, University of Brest, Brest, France

    Laurent Misery

  2. Center of Chronic Pruritus, University Hospital Münster, Münster, Nordrhein-Westfalen, Germany

    Sonja Ständer

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© 2016 Springer-Verlag London

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Le Gall-Ianotto, C., Misery, L. (2016). Pruritus in Hematological Diseases (Including Aquagenic Pruritus). In: Misery, L., Ständer, S. (eds) Pruritus. Springer, Cham. https://doi.org/10.1007/978-3-319-33142-3_36

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  • DOI: https://doi.org/10.1007/978-3-319-33142-3_36

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  • Online ISBN: 978-3-319-33142-3

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