Abstract
The effect of furosemide, glibenclamide, glimepiride, glipizide, insulin, metformin and oral contraceptives on the pharmacokinetics of pregabalin are described. Also, potential pharmacodynamic interactions are highlighted.
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Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Furosemide | Furosemide does not affect the pharmacokinetics of pregabalin [1] |
Glibenclamide ( glyburide ) | Glibenclamide does not affect the pharmacokinetics of pregabalin [1] |
Glimepiride | Glimepiride does not affect the pharmacokinetics of pregabalin [1] |
Glipizide | Glipizide does not affect the pharmacokinetics of pregabalin [1] |
Insulin | Insulin does not affect the pharmacokinetics of pregabalin [1] |
Metformin | Metformin does not affect the pharmacokinetics of pregabalin [1] |
Oral contraceptives | Oral contraceptives do not affect the pharmacokinetics of pregabalin [2] |
References
Janiczek-Dolphin N, Corrigan BW, Bockbrader HN. Diuretics, oral hypoglycaemic agents and insulin do not alter pregabalin pharmacokinetics. Epilepsia. 2005;46 (Suppl 6):115.
Bochbrader H, Miller R, Frame B, Lalonde R, Spiegel K, Barrett J. The concomitant use of pregabalin and oral contraceptives does not affect the efficacy of either agent. Epilepsia. 2005;46 (Suppl 8):170–1.
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Patsalos, P.N. (2016). Pregabalin. In: Antiepileptic Drug Interactions. Springer, Cham. https://doi.org/10.1007/978-3-319-32909-3_48
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DOI: https://doi.org/10.1007/978-3-319-32909-3_48
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