Abstract
An assessment of the morphological parameters in renal imaging is an integral point of the evaluation of kidneys’ diseases and organ growth in children. The aim of this study is to create useful pathophysiological tools that will help as to a more accurate and detailed diagnosis in kidney studies.
To estimate the volume and length of kidney in conjunction with the usage of 3D volume rendering images, we created algorithms to reconstruct and analyse the data of Technetium-99m dimercaptosuccinic acid (DMSA) scan. This study included 414 children of which 173 were boys and 241 girls, ageing from 1 month to 18 years old (infants – children – adolescents). The results of this analysis established that the renal size was larger on the left side than the right side and that there was no significant gender-related difference between them. Furthermore it was noted that a rapid renal growth occurs during the first year of life and then this growth rate stabilizes in linear fashion. From the three-dimensional images and quantitative analysis of the kidneys, we accomplished to ascribe some renal abnormalities, such as damage of renal cortex (scars), distention of the pelvis and congenital abnormalities. Our mathematical models can be applied in conjunction with other software applications of Medical Imaging, enabling the extraction of valuable quantitative, morphological and dosimetric information.
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Ttofi, E., Lyra, M. (2016). 3D SPECT Reconstruction and Analysis of Kidney Morphology in Childhood – Use of Mathematical Models. In: Kyriacou, E., Christofides, S., Pattichis, C. (eds) XIV Mediterranean Conference on Medical and Biological Engineering and Computing 2016. IFMBE Proceedings, vol 57. Springer, Cham. https://doi.org/10.1007/978-3-319-32703-7_62
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DOI: https://doi.org/10.1007/978-3-319-32703-7_62
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