Estimation of the Endotracheal Tube Pressure Drop During HFPV: A Flow-Independent Model

  • Miloš AjčevićEmail author
  • Umberto Lucangelo
  • Agostino Accardo
Conference paper
Part of the IFMBE Proceedings book series (IFMBE, volume 57)


High frequency percussive ventilation (HFPV) is a non-conventional ventilatory modality which has proven very effective and safe in patients with acute respiratory failure. HFPV ventilator measures airway pressure that represents the sum of the endotracheal tube pressure drop and the tracheal pressure dissipated to inflate a lung. The estimation of the difference between the peak airway and tracheal pressure ∆Pp may be very useful to the clinician to avoid lung injury. The aim of this study is to provide a comprehensive solution for estimation of ∆Pp in adult endotracheal tubes, by developing a flow-independent model, based on endotracheal tube size, ventilator set parameters (i.e. peak pressures, pulsatile frequencies) and patient’s respiratory system resistance and compliance. The model for the estimation of ∆Pp was determined by using the Least Absolute Shrinkage and Selection Operator (LASSO) regularized least-squares regression technique. The identified model was successively assessed on test data set.


HFPV Respiratory signal processing Model identification LASSO Endotracheal tubes 


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Miloš Ajčević
    • 1
    Email author
  • Umberto Lucangelo
    • 2
  • Agostino Accardo
    • 1
  1. 1.Department of Engineering and ArchitectureUniversity of TriesteTriesteItaly
  2. 2.Department of Perioperative Medicine, Intensive Care and Emergency, Cattinara HospitalUniversity of TriesteTriesteItaly

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