Abstract
Patient selection for nerve sparing technique during radical prostatectomy has mostly centered upon nomograms to select patient at risk for pT3 disease. In such cases, nerve sparing may lead to a positive surgical margin and need for postoperative radiation therapy. MRI may add to nerve sparing planning; however, an alternate technique is frozen section analysis. Although many pathologists frown upon the expense and accuracy of frozen section analysis, the group from the Martini clinic in Hamburg, Germany has resurrected the concept by combining surgeon-led identification of posterior-lateral tissue for frozen section analysis followed by standard histopathology analysis. The main findings point to increased utilization of nerve sparing technique without compromising cancer control. Only frozen section positive cases are then re-resected into non-nerve or partial nerve sparing planes.
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Beyer, B., Haese, A., Graefen, M. (2016). Neurovascular Structure-Adjacent Frozen-Section Examination (NeuroSAFE) in Robot-Assisted Radical Prostatectomy. In: Davis, J. (eds) Robot-Assisted Radical Prostatectomy. Springer, Cham. https://doi.org/10.1007/978-3-319-32641-2_8
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DOI: https://doi.org/10.1007/978-3-319-32641-2_8
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