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Treatment at Relapse (Surgery and Systemic Treatments)

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Ovarian Cancers

Abstract

Relapses are an important part of epithelial ovarian cancer history due to the natural course of disease and due to inadequate primary treatment. Presently, first relapse means an evolution towards a chronic disease. However, treatments at relapse as chemotherapy, targeted therapy and potentially surgery have substantially prolonged life. So, it is of particular interest to give the patient the best strategy for a better life despite recurrences. Decision making is now mainly based on the expected chemosensitivity of the disease, which was reflected until now by platinum-free interval. This has recently changed. It illustrates biological features of the tumour and host’s profile such as immune and genetics characteristics. Quality of life remains the cornerstone of treatment choice, and benefit-risk balance evaluation should be the main goal for decision.

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Correspondence to Jacobus Pfisterer MD, PhD .

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Floquet, A., Pfisterer, J. (2017). Treatment at Relapse (Surgery and Systemic Treatments). In: Pujade-Lauraine, E., Ray-Coquard, I., Lécuru, F. (eds) Ovarian Cancers. Springer, Cham. https://doi.org/10.1007/978-3-319-32110-3_10

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  • DOI: https://doi.org/10.1007/978-3-319-32110-3_10

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