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Hypertension and Brain Damage pp 159–171Cite as

Management of High Blood Pressure in Intracerebral Haemorrhage

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Part of the book series: Updates in Hypertension and Cardiovascular Protection ((UHCP))

Abstract

Although intracerebral haemorrhage (ICH) represents a minority of all strokes, it remains a significant cause of morbidity and mortality worldwide. Early BP elevation is common after ICH, with many observations showing strong associations between increasing BP values and haematoma growth and subsequent poor outcomes. Recent evidence suggests that early intensive SBP lowering in acute ICH to <140 mmHg within a few hours is feasible and safe and can be effective in improving functional outcomes. The optimal timing for initiating BP lowering after ICH is unknown. However, optimal protection against death or disability after ICH was observed in patients without severe ICH and early planned surgery who achieved the greatest SBP reductions in the first hour after randomization, which was maintained consistently for 7 days. The optimal choice of drug and intensity of treatment remain elusive. Other factors, such as BP variability, obstructive sleep apnoea, obesity and other vascular risk factors, should also be considered in the acute care of ICH patients. Current large-scale trial results are needed to determine whether control of these potentially modifiable factors may improve clinical outcomes.

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References

  1. Chin JH, Vora N (2014) The global burden of neurologic diseases. Neurology 83:349–351

    Article  PubMed  PubMed Central  Google Scholar 

  2. Feigin VL, Forouzanfar MH, Krishnamurthi R et al (2014) Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet 383:245–254

    Article  PubMed  PubMed Central  Google Scholar 

  3. O’Donnell MJ, Xavier D, Liu L et al (2010) Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet 376:112–123

    Article  PubMed  Google Scholar 

  4. Arima H, Anderson CS, Wang JG et al (2010) Lower treatment blood pressure is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage. Hypertension 56:852–858

    Article  CAS  PubMed  Google Scholar 

  5. Kazui S, Minematsu K, Yamamoto H, Sawada T, Yamaguchi T (1997) Predisposing factors to enlargement of spontaneous intracerebral hematoma. Stroke 28:2370–2375

    Article  CAS  PubMed  Google Scholar 

  6. Fogelholm R, Avikainen S, Murros K (1997) Prognostic value and determinants of first-day mean arterial pressure in spontaneous supratentorial intracerebral hemorrhage. Stroke 28:1396–1400

    Article  CAS  PubMed  Google Scholar 

  7. Vemmos KN, Tsivgoulis G, Spengos K et al (2004) U-shaped relationship between mortality and admission blood pressure in patients with acute stroke. J Intern Med 255:257–265

    Article  CAS  PubMed  Google Scholar 

  8. Ohwaki K, Yano E, Nagashima H, Hirata M, Nakagomi T, Tamura A (2004) Blood pressure management in acute intracerebral hemorrhage: relationship between elevated blood pressure and hematoma enlargement. Stroke 35:1364–1367

    Article  PubMed  Google Scholar 

  9. Okumura K, Ohya Y, Maehara A, Wakugami K, Iseki K, Takishita S (2005) Effects of blood pressure levels on case fatality after acute stroke. J Hypertens 23:1217–1223

    Article  CAS  PubMed  Google Scholar 

  10. Zhang Y, Reilly KH, Tong W et al (2008) Blood pressure and clinical outcome among patients with acute stroke in Inner Mongolia, China. J Hypertens 26:1446–1452

    Article  CAS  PubMed  Google Scholar 

  11. Sakamoto Y, Koga M, Yamagami H et al (2013) Systolic blood pressure after intravenous antihypertensive treatment and clinical outcomes in hyperacute intracerebral hemorrhage: the stroke acute management with urgent risk-factor assessment and improvement-intracerebral hemorrhage study. Stroke 44:1846–1851

    Article  CAS  PubMed  Google Scholar 

  12. Anderson CS, Heeley E, Huang Y et al (2013) Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage. N Engl J Med 368:2355–2365

    Article  CAS  PubMed  Google Scholar 

  13. Tsai C-F, Thomas B, Sudlow CLM (2013) Epidemiology of stroke and its subtypes in Chinese vs white populations: a systematic review. Neurology 81:264–272

    Article  PubMed  PubMed Central  Google Scholar 

  14. Feigin VL, Lawes CM, Bennett DA, Barker-Collo SL, Parag V (2009) Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review. Lancet Neurol 8:355–369

    Article  PubMed  Google Scholar 

  15. Van Asch CJ, Luitse MJ, Rinkel GJ, van der Tweel I, Algra A, Klijn CJ (2010) Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol 9:167–176

    Article  PubMed  Google Scholar 

  16. Poon MTC, Fonville AF, Al-Shahi SR (2014) Long-term prognosis after intracerebral haemorrhage: systematic review and meta-analysis. J Neurol Neurosurg Psychiatry 85:660–667

    Article  PubMed  Google Scholar 

  17. Portenoy RK, Lipton RB, Berger AR, Lesser ML, Lantos G (1987) Intracerebral haemorrhage: a model for the prediction of outcome. J Neurol Neurosurg Psychiatry 50:976–979

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Barber M, Roditi G, Stott DJ, Langhorne P (2004) Poor outcome in primary intracerebral haemorrhage: results of a matched comparison. Postgrad Med J 80:89–92

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Tatu L, Moulin T, El Mohamad R, Vuillier F, Rumbach L, Czorny A (2000) Primary intracerebral hemorrhages in the Besançon stroke registry. Initial clinical and CT findings, early course and 30-day outcome in 350 patients. Eur Neurol 43:209–214

    Article  CAS  PubMed  Google Scholar 

  20. Eastern Stroke and Coronary Heart Disease Collaborative Research Group (1998) Blood pressure, cholesterol, and stroke in eastern Asia. Lancet 352:1801–1807

    Article  Google Scholar 

  21. Lawes CMM, Rodgers A, Bennett DA et al (2003) Blood pressure and cardiovascular disease in the Asia Pacific region. J Hypertens 21:707–716

    Article  CAS  PubMed  Google Scholar 

  22. Arakawa S, Saku Y, Ibayashi S, Nagao T, Fujishima M (1998) Blood pressure control and recurrence of hypertensive brain hemorrhage. Stroke 29:1806–1809

    Article  CAS  PubMed  Google Scholar 

  23. Ariesen MJ, Claus SP, Rinkel GJE, Algra A (2003) Risk factors for intracerebral hemorrhage in the general population: a systematic review. Stroke 34:2060–2065

    Article  CAS  PubMed  Google Scholar 

  24. Rapsomaniki E, Timmis A, George J et al (2014) Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1 · 25 million people. Lancet 383:1899–1911

    Article  PubMed  PubMed Central  Google Scholar 

  25. Thrift AG, McNeil JJ, Forbes A, Donnan GA (1998) Three important subgroups of hypertensive persons at greater risk of intracerebral hemorrhage. Hypertension 31:1223–1229

    Article  CAS  PubMed  Google Scholar 

  26. Meretoja A, Strbian D, Putaala J et al (2012) SMASH-U: a proposal for etiologic classification of intracerebral hemorrhage. Stroke 43:2592–2597

    Article  PubMed  Google Scholar 

  27. Yeh S-J, Tang S-C, Tsai L-K, Jeng J-S (2014) Pathogenetical subtypes of recurrent intracerebral hemorrhage: designations by SMASH-U classification system. Stroke 45:2636–2642

    Article  PubMed  Google Scholar 

  28. Sessa M (2008) Intracerebral hemorrhage and hypertension. Neurol Sci 29(Suppl 2):S258–S259

    Article  PubMed  Google Scholar 

  29. Mizukami M, Kin H, Araki G, Mihara H, Yoshida Y (1976) Surgical treatment of primary intracerebral hemorrhage- part 1: new angiographical classification. Stroke 7:30–36

    Article  CAS  PubMed  Google Scholar 

  30. Davis SM, Broderick J, Hennerici M et al (2006) Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage. Neurology 66:1175–1181

    Article  CAS  PubMed  Google Scholar 

  31. Brott T, Broderick J, Kothari R et al (1997) Early hemorrhage growth in patients with intracerebral hemorrhage. Stroke 28:1–5

    Article  CAS  PubMed  Google Scholar 

  32. Fujii Y, Tanaka R, Takeuchi S, Koike T, Minakawa T, Sasaki O (1994) Hematoma enlargement in spontaneous intracerebral hemorrhage. J Neurosurg 80:51–57

    Article  CAS  PubMed  Google Scholar 

  33. Kazui S, Naritomi H, Yamamoto H, Sawada T, Yamaguchi T (1996) Enlargement of spontaneous intracerebral hemorrhage. Incidence and time course. Stroke 27:1783–1787

    Article  CAS  PubMed  Google Scholar 

  34. Flibotte JJ, Hagan N, O’Donnell J, Greenberg SM, Rosand J (2004) Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology 63:1059–1064

    Article  CAS  PubMed  Google Scholar 

  35. Gebel JM, Jauch EC, Brott TG et al (2002) Natural history of perihematomal edema in patients with hyperacute spontaneous intracerebral hemorrhage. Stroke 33:2631–2635

    Article  PubMed  Google Scholar 

  36. Carhuapoma JR, Hanley DF, Banerjee M, Beauchamp NJ (2003) Brain edema after human cerebral hemorrhage: a magnetic resonance imaging volumetric analysis. J Neurosurg Anesthesiol 15:230–233

    Article  PubMed  Google Scholar 

  37. Gong C, Hoff JT, Keep RF (2000) Acute inflammatory reaction following experimental intracerebral hemorrhage in rat. Brain Res 871:57–65

    Article  CAS  PubMed  Google Scholar 

  38. Xue M, Del Bigio MR (2000) Intracortical hemorrhage injury in rats: relationship between blood fractions and brain cell death. Stroke 31:1721–1727

    Article  CAS  PubMed  Google Scholar 

  39. Wallace JD, Levy LL (1981) Blood pressure after stroke. JAMA 246:2177–2180

    Article  CAS  PubMed  Google Scholar 

  40. Harper G, Castleden CM, Potter JF (1994) Factors affecting changes in blood pressure after acute stroke. Stroke 25:1726–1729

    Article  CAS  PubMed  Google Scholar 

  41. Robinson TG, Potter JF (2004) Blood pressure in acute stroke. Age Ageing 33:6–12

    Article  PubMed  Google Scholar 

  42. Qureshi AI, Ezzeddine MA, Nasar A et al (2007) Prevalence of elevated blood pressure in 563,704 adult patients with stroke presenting to the ED in the United States. Am J Emerg Med 25:32–38

    Article  PubMed  PubMed Central  Google Scholar 

  43. Fischer U, Cooney MT, Bull LM et al (2014) Acute post-stroke blood pressure relative to premorbid levels in intracerebral haemorrhage versus major ischaemic stroke: a population-based study. Lancet Neurol 13:374–384

    Article  PubMed  PubMed Central  Google Scholar 

  44. Zahuranec DB, Wing JJ, Edwards DF et al (2012) Poor long-term blood pressure control after intracerebral hemorrhage. Stroke 43:2580–2585

    Article  PubMed  PubMed Central  Google Scholar 

  45. Qureshi AI, Mendelow AD, Hanley DF (2009) Intracerebral haemorrhage. Lancet 373:1632–1644

    Article  PubMed  PubMed Central  Google Scholar 

  46. Fodstad H, Kelly PJ, Buchfelder M (2006) History of the cushing reflex. Neurosurgery 59:1132–1137; discussion 1137

    PubMed  Google Scholar 

  47. Willmot M, Leonardi-Bee J, Bath PMW (2004) High blood pressure in acute stroke and subsequent outcome: a systematic review. Hypertension 43:18–24

    Article  CAS  PubMed  Google Scholar 

  48. Manning L, Hirakawa Y, Arima H et al (2014) Blood pressure variability and outcome after acute intracerebral haemorrhage: a post-hoc analysis of INTERACT2, a randomised controlled trial. Lancet Neurol 13:364–373

    Article  PubMed  Google Scholar 

  49. Becker KJ, Baxter AB, Bybee HM, Tirschwell DL, Abouelsaad T, Cohen WA (1999) Extravasation of radiographic contrast is an independent predictor of death in primary intracerebral hemorrhage. Stroke 30:2025–2032

    Article  CAS  PubMed  Google Scholar 

  50. Daverat P, Castel JP, Dartigues JF, Orgogozo JM (1991) Death and functional outcome after spontaneous intracerebral hemorrhage. A prospective study of 166 cases using multivariate analysis. Stroke 22:1–6

    Article  CAS  PubMed  Google Scholar 

  51. Tuhrim S, Dambrosia JM, Price TR et al (1991) Intracerebral hemorrhage: external validation and extension of a model for prediction of 30-day survival. Ann Neurol 29:658–663

    Article  CAS  PubMed  Google Scholar 

  52. Mayer SA, Sacco RL, Shi T, Mohr JP (1994) Neurologic deterioration in noncomatose patients with supratentorial intracerebral hemorrhage. Neurology 44:1379–1384

    Article  CAS  PubMed  Google Scholar 

  53. Leira R, Dávalos A, Silva Y et al (2004) Early neurologic deterioration in intracerebral hemorrhage: predictors and associated factors. Neurology 63:461–467

    Article  CAS  PubMed  Google Scholar 

  54. Lisk DR, Pasteur W, Rhoades H, Putnam RD, Grotta JC (1994) Early presentation of hemispheric intracerebral hemorrhage: prediction of outcome and guidelines for treatment allocation. Neurology 44:133–139

    Article  CAS  PubMed  Google Scholar 

  55. Fujii Y, Takeuchi S, Sasaki O, Minakawa T, Tanaka R (1998) Multivariate analysis of predictors of hematoma enlargement in spontaneous intracerebral hemorrhage. Stroke 29:1160–1166

    Article  CAS  PubMed  Google Scholar 

  56. Arima H, Tzourio C, Butcher K et al (2006) Prior events predict cerebrovascular and coronary outcomes in the PROGRESS trial. Stroke 37:1497–1502

    Article  PubMed  Google Scholar 

  57. Hanger HC, Wilkinson TJ, Fayez-Iskander N, Sainsbury R (2007) The risk of recurrent stroke after intracerebral haemorrhage. J Neurol Neurosurg Psychiatry 78:836–840

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  58. Izumihara A, Suzuki M, Ishihara T (2005) Recurrence and extension of lobar hemorrhage related to cerebral amyloid angiopathy: multivariate analysis of clinical risk factors. Surg Neurol 64:160–164; discussion 164

    Article  PubMed  Google Scholar 

  59. Inagawa T (2005) Recurrent primary intracerebral hemorrhage in Izumo City, Japan. Surg Neurol 64:28–35; discussion 35–6

    Article  PubMed  Google Scholar 

  60. Zahuranec DB, Gonzales NR, Brown DL et al (2006) Presentation of intracerebral haemorrhage in a community. J Neurol Neurosurg Psychiatry 77:340–344

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  61. Langhorne P, Fearon P, Ronning OM et al (2013) Stroke unit care benefits patients with intracerebral hemorrhage: systematic review and meta-analysis. Stroke 44:3044–3049

    Article  PubMed  Google Scholar 

  62. Anderson CS, Huang Y, Wang JG et al (2008) Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. Lancet Neurol 7:391–399

    Article  PubMed  Google Scholar 

  63. Qureshi AI, Bliwise DL, Bliwise NG, Akbar MS, Uzen G, Frankel MR (1999) Rate of 24-hour blood pressure decline and mortality after spontaneous intracerebral hemorrhage: a retrospective analysis with a random effects regression model. Crit Care Med 27:480–485

    Article  CAS  PubMed  Google Scholar 

  64. Kidwell CS, Heiss W-D (2012) Advances in stroke: imaging. Stroke 43:302–304

    Article  PubMed  Google Scholar 

  65. Kim-Han JS, Kopp SJ, Dugan LL, Diringer MN (2006) Perihematomal mitochondrial dysfunction after intracerebral hemorrhage. Stroke 37:2457–2462

    Article  PubMed  Google Scholar 

  66. Powers WJ, Zazulia AR, Videen TO et al (2001) Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage. Neurology 57:18–24

    Article  CAS  PubMed  Google Scholar 

  67. Anderson CS, Huang Y, Arima H et al (2010) Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT). Stroke 41:307–312

    Article  PubMed  Google Scholar 

  68. Qureshi AI, Palesch YY, Martin R et al (2010) Effect of systolic blood pressure reduction on hematoma expansion, perihematomal edema, and 3-month outcome among patients with intracerebral hemorrhage: results from the antihypertensive treatment of acute cerebral hemorrhage study. Arch Neurol 67:570–576

    Article  PubMed  Google Scholar 

  69. Koch S, Romano JG, Forteza AM, Otero CM, Rabinstein AA (2008) Rapid blood pressure reduction in acute intracerebral hemorrhage: feasibility and safety. Neurocrit Care 8:316–321

    Article  PubMed  Google Scholar 

  70. Xu M (2011) Effect of blood pressure lowering strategy on the enlargement of hematoma and clinical outcome in patients with acute intracerebral haemorrhage. Chinese J Cerebrovasc Dis 8:23–27

    Google Scholar 

  71. Meyer JS, Bauer RB (1962) Medical treatment of spontaneous intracranial hemorrhage by the use of hypotensive drugs. Neurology 12:36–47

    Article  CAS  PubMed  Google Scholar 

  72. Suri MFK, Suarez JI, Rodrigue TC et al (2008) Effect of treatment of elevated blood pressure on neurological deterioration in patients with acute intracerebral hemorrhage. Neurocrit Care 9:177–182

    Article  PubMed  Google Scholar 

  73. Itabashi R, Toyoda K, Yasaka M et al (2008) The impact of hyperacute blood pressure lowering on the early clinical outcome following intracerebral hemorrhage. J Hypertens 26:2016–2021

    Article  CAS  PubMed  Google Scholar 

  74. Powers WJ (1993) Acute hypertension after stroke: the scientific basis for treatment decisions. Neurology 43:461–467

    Article  CAS  PubMed  Google Scholar 

  75. Kuwata N, Kuroda K, Funayama M, Sato N, Kubo N, Ogawa A (1995) Dysautoregulation in patients with hypertensive intracerebral hemorrhage. A SPECT study. Neurosurg Rev 18:237–245

    Article  CAS  PubMed  Google Scholar 

  76. Morgenstern LB, Hemphill JC, Anderson C et al (2010) Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 41:2108–2129

    Article  PubMed  PubMed Central  Google Scholar 

  77. Bath P, Chalmers J, Powers W et al (2003) International Society of Hypertension (ISH): statement on the management of blood pressure in acute stroke. J Hypertens 21:665–672

    Article  PubMed  Google Scholar 

  78. Stroke Foundation of New Zealand and New Zealand Guidelines Group (2010) Clinical guidelines for stroke management 2010. Stroke Foundation of New Zealand, Wellington

    Google Scholar 

  79. Qureshi AI (2007) Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH): rationale and design. Neurocrit Care 6:56–66

    Article  CAS  PubMed  Google Scholar 

  80. Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) Investigators (2010) Antihypertensive treatment of acute cerebral hemorrhage. Crit Care Med 38:637–648

    Article  Google Scholar 

  81. Sandset EC, Bath PMW, Boysen G et al (2011) The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial. Lancet 377:741–750

    Article  CAS  PubMed  Google Scholar 

  82. Hemphill JC, Greenberg SM, Anderson CS et al (2015) Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 46:2032–2060

    Article  PubMed  Google Scholar 

  83. Arima H, Heeley E, Delcourt C et al (2015) Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2. Neurology 84:464–471

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  84. Wang X, Arima H, Heeley E et al (2015) Magnitude of blood pressure reduction and clinical outcomes in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial study. Hypertension 65:1026–1032

    Article  CAS  PubMed  Google Scholar 

  85. Sakamoto Y, Koga M, Todo K et al (2015) Relative systolic blood pressure reduction and clinical outcomes in hyperacute intracerebral hemorrhage: the SAMURAI-ICH observational study. J Hypertens 33:1069–1073

    Article  CAS  PubMed  Google Scholar 

  86. Steiner T, Al-Shahi Salman R, Beer R et al (2014) European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage. Int J Stroke 9:840–855

    Article  PubMed  Google Scholar 

  87. Grysiewicz RA, Ruland SD (2011) Hypertensive encephalopathy and acute blood pressure management after hemorrhagic stroke. In: Aiyagari V, Gorelick P (eds) Hypertension and stroke. Pathophysiology and management. Humana Press, New York

    Google Scholar 

  88. Pontes-Neto OM, Fernandes RMF, Sander HH et al (2010) Obstructive sleep apnea is frequent in patients with hypertensive intracerebral hemorrhage and is related to perihematoma edema. Cerebrovasc Dis 29:36–42

    Article  PubMed  Google Scholar 

  89. Woo D, Sauerbeck LR, Kissela BM et al (2002) Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study. Stroke 33:1190–1195

    Article  PubMed  Google Scholar 

  90. Gee P, Tallon C, Long N, Moore G, Boet R, Jackson S (2012) Use of recreational drug 1,3 Dimethylamylamine (DMAA) [corrected] associated with cerebral hemorrhage. Ann Emerg Med 60:431–434

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Neurology for Adults, Medical University of Gdansk, Gdansk, Poland

    Dariusz Gasecki & Bartosz Karaszewski

  2. Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland

    Krzysztof Narkiewicz

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  1. Dariusz Gasecki
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  2. Bartosz Karaszewski
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  3. Krzysztof Narkiewicz
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Correspondence to Dariusz Gasecki .

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  1. Hypertension & Vascular Risk Unit, Hospital Clínic, Barcelona, Spain

    Antonio Coca

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Gasecki, D., Karaszewski, B., Narkiewicz, K. (2016). Management of High Blood Pressure in Intracerebral Haemorrhage. In: Coca, A. (eds) Hypertension and Brain Damage. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-319-32074-8_12

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