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Hyperbaric Oxygen Therapy for Critical Limb Ischemia

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Critical Limb Ischemia

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Abstract

Tissue hypoxia as a result of arterial insufficiency can lead to tissue injury and loss. Compromised tissue due to ischemia, even after prompt restoration of arterial flow, following acute injury can be further damaged through the complex processes of reperfusion injury. Threatened tissue due to chronic limb ischemia can manifest as chronic ischemic wounds and rest pain. Hyperbaric oxygen therapy (HBO) is an important tool in hypoxic tissue management by significantly increasing plasma oxygen concentration and oxygen capillary diffusion distance. This chapter will review important physiologic mechanisms of HBO in the management of ischemic injury as well as potential applications to clinical scenarios of ischemia, including critical limb ischemia.

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Authors and Affiliations

  1. Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USA

    Raymond C. Shields MD

  2. Division of Cardiovascular Diseases, and Preventive, Occupational, and Aerospace Medicine, Mayo clinic, Rochester, MN, USA

    Raymond C. Shields MD

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  1. Raymond C. Shields MD
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Editors and Affiliations

  1. Loyola University Medical Center, Maywood, Illinois, USA

    Robert S. Dieter

  2. Northwestern Medicine Central DuPage Hospital, Glen Ellyn, Illinois, USA

    Raymond A. Dieter, Jr

  3. The University of Tennessee Medical Center, Knoxville, Tennessee, USA

    Raymond A. Dieter, III

  4. West Virginia University, Charleston, West Virginia, USA

    Aravinda Nanjundappa

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Shields, R.C. (2017). Hyperbaric Oxygen Therapy for Critical Limb Ischemia. In: Dieter, R., Dieter, Jr, R., Dieter, III, R., Nanjundappa, A. (eds) Critical Limb Ischemia. Springer, Cham. https://doi.org/10.1007/978-3-319-31991-9_43

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  • DOI: https://doi.org/10.1007/978-3-319-31991-9_43

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