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Stem Cell Proteomics

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Manual of Cardiovascular Proteomics

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Abstract

Recent advances in stem cell and proteomic technology carry tremendous potential to impact our understanding of mechanistic underpinnings and fundamental pathophysiology of cardiovascular disease. In this chapter, we introduce investigators new to these disciplines to the various types of stem cells relevant to cardiovascular biology and how, when combined with state-of-the-art proteomic analyses, they may be exploited for mechanistic and translational studies related to cardiomyopathies, coronary atherosclerotic disease, and heart failure. Although the potential of these emerging technologies is just beginning to be explored, this chapter aims to illustrate how integration of novel stem cell and proteomic technologies is poised to make significant contributions to future advanced therapies and diagnostics in cardiovascular medicine.

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Acknowledgements

This work was supported by American Heart Association 15GRNT24980002 to R.G. and NIH grant R01HL094384 to A.S.O. E.K. is a member of the Medical Scientist Training Program at the Medical College of Wisconsin, which is partially supported by an NIH T32 grant GM080202. S.F. was partially supported by an American College of Cardiology Fellowship.

Author information

Authors and Affiliations

  1. Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, 53226, USA

    Matthew Waas, Erin M. Kropp & Rebekah L. Gundry PhD

  2. Division of Cardiology, Department of Internal Medicine, University of Washington Medical Center, Seattle, WA, 98195, USA

    Stephen Farris MD, Jennifer A. Beckman MSN, BSN, April Stempien-Otero MD & Claudius Mahr DO, FACC, FESC

  3. Department of Internal Medicine, University of Washington, Seattle, WA, USA

    Claudius Mahr DO, FACC, FESC

Authors
  1. Matthew Waas
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  2. Stephen Farris MD
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  3. Erin M. Kropp
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  4. Jennifer A. Beckman MSN, BSN
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  5. April Stempien-Otero MD
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  6. Claudius Mahr DO, FACC, FESC
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  7. Rebekah L. Gundry PhD
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Corresponding author

Correspondence to Rebekah L. Gundry PhD .

Editor information

Editors and Affiliations

  1. Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Giulio Agnetti

  2. Dept. of Physiology & Biophysics, University Mississippi Medical Center, Jackson, Mississippi, USA

    Merry L. Lindsey

  3. Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    D. Brian Foster

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© 2016 Springer International Publishing Switzerland

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Waas, M. et al. (2016). Stem Cell Proteomics. In: Agnetti, G., Lindsey, M., Foster, D. (eds) Manual of Cardiovascular Proteomics. Springer, Cham. https://doi.org/10.1007/978-3-319-31828-8_6

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  • DOI: https://doi.org/10.1007/978-3-319-31828-8_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31826-4

  • Online ISBN: 978-3-319-31828-8

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