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Treatment of Childhood-Onset Bipolar Disorder

  • Dana Baker Kaplin
  • Robert L. FindlingEmail author
Chapter
Part of the Milestones in Drug Therapy book series (MDT)

Abstract

Pediatric bipolar disorder (PBD) is a serious condition, and a substantive need exists for evidence-based treatments for children and adolescents suffering from this condition. A fundamental intervention used in this patient population is pharmacotherapy. Despite the importance of medication treatment in this patient population, only limited amounts of methodologically stringent data exist pertaining to this form of intervention. The evidence that does exist suggests that some psychotropic medications can provide salutary effects for youths suffering from bipolar I disorder (BD-I). Also relevant is the pharmacotherapy of genetically at-risk children suffering from bipolar spectrum disorder and treatment of psychiatric comorbidities. Further placebo-controlled trials are needed in order to better characterize the efficacy and safety of psychotropic medications in this population.

Keywords

Pediatric bipolar disorder Pharmacotherapy Acute treatment Maintenance therapy Children Adolescents 

Notes

Acknowledgments/Disclosures

Dr. Findling receives or has received research support, acted as a consultant, and/or served on a speaker’s bureau for Alcobra, American Academy of Child & Adolescent Psychiatry, American Physician Institute, American Psychiatric Press, AstraZeneca, Bracket, Bristol-Myers Squibb, CogCubed, Cognition Group, Coronado Biosciences, Dana Foundation, Elsevier, Forest, GlaxoSmithKline, Guilford Press, Johns Hopkins University Press, Johnson and Johnson, Jubilant Clinsys, KemPharm, Lilly, Lundbeck, Merck, NIH, Neurim, Novartis, Noven, Otsuka, Oxford University Press, Pfizer, Physicians Postgraduate Press, Purdue, Rhodes Pharmaceuticals, Roche, Sage, Shire, Sunovion, Supernus Pharmaceuticals, Transcept Pharmaceuticals, Validus, and WebMD. Ms. Kaplin has no conflict of interest to disclose, financial or otherwise.

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Copyright information

© Springer International Publishing Switzerland (outside the USA)  2016

Authors and Affiliations

  1. 1.Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral SciencesJohns Hopkins University School of MedicineBaltimoreUSA
  2. 2.The Johns Hopkins Hospital, Bloomberg Children’s Center; Kennedy Krieger InstituteBaltimoreUSA

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