Abstract
While the entity which is currently known as scleromyxedema had been described as early as 1906, the term did not become of dermatologic lexicon until the work of Gottron in 1954. At this time it became clear that scleromyxedema was a unique entity, sharing features of the benign cutaneous mucinoses and scleroderma, with specific, recognizable morphologic features. Scleromyxedema is a rare condition, which occurs without gender predilection, usually in the 6th decade of life. Eighty percent of patients will have an associated paraproteinemia, the most common being composed of IgG heavy chain and gamma light chain. A small percentage develop multiple myeloma or have this diagnosis at the time of development of skin manifestations.
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Crowe, D.R. (2016). Scleromyxedema. In: Crowe, D., Morgan, M., Somach, S., Trapp, K. (eds) Deadly Dermatologic Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-31566-9_22
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DOI: https://doi.org/10.1007/978-3-319-31566-9_22
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