Skip to main content
SpringerLink
Log in

Full Breast Ultrasonography of Malignant Lesions

  • Chapter
  • First Online:
Atlas of Full Breast Ultrasonography

  • 1526 Accesses

Abstract

The main clinical aspects of breast cancer and ultrasonography are discussed and illustrated, including risk factors, prevention, the pathological aspects that determine image forming in mammography, and ductal echography. The old and new criteria for diagnosis using ultrasonography are discussed, along with the concepts of multicentric and multifocal cancer in ductal anatomical interpretation, which are important in the assessment of the extent of disease and to avoid risk of recurrence of breast cancer with conservative surgery. Other advantages of full breast ultrasonography include its ability to diagnose particular types of the breast cancer and lymph node metastases.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Tot T (2007) The theory of the sick breast lobe and the possible consequences. Int J Surg Pathol 1:68–71

    Google Scholar 

  2. Georgescu AC, Andrei EM, Enachescu V, Bondari S (2013) New horizons in breast Doppler ductal echography: the positive and differential diagnosis of ductal ectasia, with etiopathological correlations. ECR, Vienna, EPOSTM. doi:10.1594/ecr2013/C-0667

  3. Grio R, Cellura A, Germao R et al (1998) Clinical efficacy of tamoxifen in the treatment of premenstrual mastodynia. Minerva Ginecol 50(3):101–103

    Google Scholar 

  4. Fujimoto Y, Hatama M, Tezuka K, Otani H et al (2005) Ultrasonic screening of the thyroid in the patients with breast complaints. In: Research and development in breast ultrasound. Springer, Tokyo, pp 167–169

    Chapter  Google Scholar 

  5. Fujimoto Y, Kato Y, Maekawa H et al (1988) Ultrasonic screening of thyroid in the patients with breast complaints. J Ultrasound Med 7:39–S283

    Google Scholar 

  6. Georgescu AC, Andrei ME, Manda A, Bondari S, Sendroiu I (2015) Contributions of imaging examinations in the diagnosis of the von Recklinghausen disease. ECR, Vienna, EPOSTM. doi:10.1594/ecr2015/C-1014

  7. Szymanowski K, Niepsuj-Biniaś J, Dera-Szymanowska A et al (2013) An influence of immunomodulation on Th1 and Th2 immune response in endometriosis in an animal model. Biomed Res Int 2013, Article ID 849492:7. doi:10.1155/2013/849492

    Google Scholar 

  8. Szymanowski K, Chmaj-Wierzchowska K, Yantczenko A et al (2009) Endometriosis prophylaxis and treatment with the newly developed xenogenic immunomodulator RESAN in an animal model. Eur J Obstet Gynecol Reprod Biol 142(2):145–148

    Article  CAS  PubMed  Google Scholar 

  9. Foschini MP, Baldovini C, Ishikawa Y, Eusebi V (2012) The value of large sections in surgical pathology. Int J Breast Cancer 2012, Article ID 785947:7. doi:10.1155/2012/785947

    Google Scholar 

  10. Cheatle GL (1906) Early recognition of cancer of the breast. Br Med J 1:1205–1210

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Cheatle GL (1914) The relation between ducts and acini to cysts and cancer of the breast. J R Soc Med 7:241–244

    CAS  Google Scholar 

  12. Wellings SR, Jensen HM (1973) On the origin and progression of ductal carcinoma in the human breast. J Natl Cancer Inst 50(5):1111–1116

    CAS  PubMed  Google Scholar 

  13. Foschini MP, Flamminio F, Miglio R et al (2007) The impact of large sections on the study of in situ and invasive duct carcinoma of the breast. Hum Pathol 38(12):1736–1743

    Article  PubMed  Google Scholar 

  14. Tot T (2010) Cost-benefit analysis of using large-format histology sections in routine diagnostic breast care. Breast 19(4):284–288

    Article  PubMed  Google Scholar 

  15. Tot T (2007) Clinical relevance of the distribution of the lesions in 500 consecutive breast cancer cases documented in large–format histologic sections. Cancer 110:2551–2560

    Article  PubMed  Google Scholar 

  16. Egan RL (1982) Multicentric breast carcinomas: clinical-radiographic-pathologic whole organ studies and 10-year survival. Cancer 49(6):1123–1130

    Article  CAS  PubMed  Google Scholar 

  17. Tot T, Gere M, Pekár G et al (2011) Breast cancer multifocality, disease extent, and survival. Hum Pathol 42(11):1761–1769

    Article  PubMed  Google Scholar 

  18. Martin JE (1988) Atlas of mammography. Histologic and mammographic correlations, 2nd edn. Williams & Wilkins, Baltimore, pp 69–268

    Google Scholar 

  19. Gallager HS, Martin JE (1969) The study of breast carcinoma by correlated mammography and subserial whole organ sectioning. Early observations. Cancer 23:855–873

    Article  CAS  PubMed  Google Scholar 

  20. Gallager HS, Martin JE (1969) Early phases in the development of breast cancer. Cancer 24:1170–1178

    Article  CAS  PubMed  Google Scholar 

  21. Teboul M (2010) Advantages of ductal echography (DE) over conventional breast investigation in the diagnosis of breast malignancies. Med Ultrason 12(1):32–42

    PubMed  Google Scholar 

  22. Baldovini C, Foschini MP (2012) Multifocality of breast cancer. In: Proceedings of the 27th congress of the Adriatic Society of Pathology, June 2012

    Google Scholar 

  23. Cooper AP (1840) On the anatomy of the breast. London, Longman, Orme, Green, Brown, and Longmans. (special collections, Scott Memorial Library, Thomas Jefferson University, http://jdc.jefferson.edu/cooper/)

  24. Sobin LH, Gospodarowicz MK, Wittekind C (eds) (2009) TNM classification of malignant tumors. 7th edn. Wiley Blackwell

    Google Scholar 

  25. Saslow D, Solomon D, Lawson H et al (2012) American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. CA Cancer J Clin 62(30):147–172, Epub, Mar 14

    Article  PubMed  PubMed Central  Google Scholar 

  26. American Cancer Society Guidelines for the Early Detection of Cancer (2014) www.cancer.org

  27. Amy D (2010) Lobar Ultrasound of the Breast. In: Breast Cancer, 1.T. Tot (ed). © Springer-Verlag London Limited. doi: 10.1007/978-1-84996-314-5_8

    Google Scholar 

  28. Amy D (2003) Sub-centimetric breast carcinoma. Echographic diagnosis. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  29. Stavros AT, Rapp LC, Parker HS (2004) Breast ultrasound. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  30. Mendelson EB, Baum JK, Berg WA et al (2003) Breast imaging reporting and data system BI-RADS: ultrasound, 1st edn. American College of Radiology, Reston

    Google Scholar 

  31. JSUM guidelines for mass image-forming lesions (2005) In: Ueno E, Shiina M, Kuboto K (eds) Research and development in breast ultrasound. Springer, Tokyo. pp 78–84

    Google Scholar 

  32. Japan Society of Ultrasonics in Medicine and JABTS- (Draft) (2003) Diagnostic guideline for mass image forming lesions. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  33. Chang R-F, Huang SF, Chen D-R, Moon WK (2003) Detection of spiculation in three-dimensional breast ultrasound. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  34. Kujiraoka Y, Ueno E, Yohno E, Morishima I, Tsunoda-Shimizu H (2005) Incident angle of the plunging artery of breast tumors. In: Research and development in breast ultrasound. Springer, Tokyo, pp 72–75

    Chapter  Google Scholar 

  35. LeCarpentier G (2008) 3D Doppler evaluation helps identify malignant breast lesions. Reuters Health. Radiology 249

    Google Scholar 

  36. Chou H-I (2003) Evaluation of periductal angiogenesis using contrast-enhanced ultrasound. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  37. Ricci P, Cantisani V, Ballesio L et al (2007) Benign and malignant breast lesions: efficacy of real time contrast-enhanced ultrasound vs. magnetic resonance imaging. Ultraschall Med 28(1):57–62, PMID: 17304413 [PubMed – indexed for MEDLINE]

    Article  CAS  PubMed  Google Scholar 

  38. Drudi FM, Cantisani V, Gnecchi M (2012) Contrast-enhanced ultrasound examination of the breast: a literature review. Ultraschall Med 33(7):E1–E7. doi:10.1055/s-0031-1299408, Epub 2012 May

    CAS  PubMed  Google Scholar 

  39. Watermann DO, Foldi M, Hanjalic-Beck A et al (2005) Three-dimensional ultrasound for the assessment of breast lesions. Ultrasound Obstet Gynecol 25:592–598

    Article  CAS  PubMed  Google Scholar 

  40. Vallone P, D’Angelo R, Filice S, Petrosino T, Rinaldo M, De Chiara A, Gallipoloi A (2005) Color-doppler using contrast medium in evaluating the response to neoadjuvant treatment in patients with locally advanced breast carcinoma. Anticancer Res 25:595–599, PubMed

    PubMed  Google Scholar 

  41. Singh S, Pradhan S, Shukla RC, Ansari MA, Kumar A (2005) Color doppler ultrasound as an objective assessment tool for chemotherapeutic response in advanced breast cancer. Breast Cancer 12:45–51

    Article  PubMed  Google Scholar 

  42. Kumar A, Singh S, Pradhan S et al (2007) Doppler ultrasound scoring to predict chemotherapeutic response in advanced breast cancer. World J Surg Oncol 5:99. doi:10.1186/1477-7819-5-99

    Article  PubMed  PubMed Central  Google Scholar 

  43. Chung SY, Yang I, Kim D, Shin SJ, Bae SH (2003) Characteristic US findings of inflammatory breast carcinoma: comparison with MR imaging. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  44. Lee KW, Chung SY, Yang I, Kim HD et al (2005) Inflammatory breast cancer. Clin Imaging 29(1):22–25. doi:10.1016/j.clinimag.2004.03.006

    PubMed  Google Scholar 

  45. Papotti M, Gugliotta P, Ghiringhello B, Busolati G (1984) Association of breast carcinoma and multiple intraductal papillomas: an histological and immunohistochemical investigation. Histopathology 8(6):963–975

    Article  CAS  PubMed  Google Scholar 

  46. Saad RS, Kanbour-Shakir A, Syed A, Kanbour A (2006) Sclerosing papillary lesion of the breast: a diagnosting pitfall for malignancy in fine needle aspiration biopsy. Diagn Cytopathol 34(2):114–118

    Article  PubMed  Google Scholar 

  47. Lefkowitz M, Lefkowitz W, Wargotz ES (1994) Intraductal (intracystic) papillary carcinoma of the breast and its variants: a clinicopathological study of 77 cases. Hum Pathol 25(8):802–809

    Article  CAS  PubMed  Google Scholar 

  48. Ueng S-H, Mezzetti T, Tavassoli AF (2009) Papillary neoplasms of the breast: a review. Arch Pathol Lab Med 133(6):893–907

    PubMed  Google Scholar 

  49. Svane G (2005) Ductal Carcinoma in Situ (DCIS): incidence, prognosis, and diagnostic aspects on mammography, galactography, and needle biopsies. In: Research and development in breast ultrasound. Springer, Tokyo, pp 114–118

    Chapter  Google Scholar 

  50. Takebe K, Izumori A (2005) The ultrasonographic diagnosis of nonpalpable DCIS without calcification on mammography and nipple discharge: advocacy of a new term, 3 non-DCIS. In: Research and development in breast ultrasound. Springer, Tokyo, pp 119–126

    Chapter  Google Scholar 

  51. Tanaka K, Sakuma H, Sakamoto G et al (2005) Characteristic mammography and ultrasonography findings of ductal carcinoma in situ of the breast arising in sclerosing adenosis. In: Research and development in breast ultrasound. Springer, Tokyo, pp 135–140

    Chapter  Google Scholar 

  52. Silverstein MJ, Recht A, Lagios M (eds) (2002) Ductal carcinoma in situ of the breast, 2nd edn. Silverstein/Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  53. Kim EK, Oh KK, Shin HC (1996) Paget’s disease of the breast: significance of mammographic findings. J Korean Radiol Soc 34(4):551–555

    Google Scholar 

  54. Choi SH, Chung SY, Lee KW et al (2001) Ultrasonography in Paget’s disease of the breast: comparison with mammographic findings. J Korean Soc Med Ultrasound 20(20):137–142

    Google Scholar 

  55. Bacchetta J, Juillard L, Cochat P et al (2009) Paraneoplastic glomerular diseases and malignancies. Crit Rev Oncol Hematol 70:39–58

    Article  PubMed  Google Scholar 

  56. Kijima Y, Yoshinaka H, Owaki T et al (2004) Breast cancer with nephrotic syndrome: report of two cases. Surg Today 34(9):755–759

    Article  PubMed  Google Scholar 

  57. Valcamonico F, Ferrari V, Simoncini E et al (2004) Paraneoplastic nephrotic syndrome in advanced breast cancer patient. A case report. Tumori 90(1):154–156

    PubMed  Google Scholar 

  58. Yoshizawa H, Akimoto T, Nishino K et al (2011) Nephrotic syndrome and renal failure in a patient with metastatic breast cancer. Clin Exp Nephrol 15(4):567–571. doi:10.007/s10157-011-0425-1, Epub 2011Mar 18

    Article  CAS  PubMed  Google Scholar 

  59. Oh KK (2003) The Paget’s disease and pagetoid extension of the breast cancers: 3-D sonographic and pathologic correlation. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  60. Sakita I, Yoshida T, Sohma I, Fukuchi N, Izawa H, Ebisui C, Hasuike Y, Ishizawa H, Kobayashi Y, Kotera I, Fujimoto T (2003) Determination of indication for sentinel lymph node biopsy using Doppler imaging. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  61. Wisner ER, Ferrara KW, Short RE, Ottoboni TB, Gabe JD, Patel D (2003) Sentinel node detection using contrast-enhanced power doppler ultrasound lymphography. Invest Radiol 38(60):358–365

    PubMed  Google Scholar 

  62. Britton PD, Goud A, Godward S, Barter S et al (2009) Use of ultrasound-guided axillary node core biopsy in staging of early breast cancer. Eur Radiol 19(3):561–569

    Article  CAS  PubMed  Google Scholar 

  63. Chung SY, Kim E-K, Oh KK (2003) Imaging findings of axillary abnormalities.13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  64. Okamoto T, Horiuchi K, Kodama H et al (2005) Probability of axillary lymph node metastasis when sentinel lymph node biopsy is negative in women with clinically node negative breast cancer: a Bayesian approach. Breast Cancer 02/12(3):203–210. doi:10.2325/jbcs.12.203

    Google Scholar 

  65. Kusama M, Kawamoto A, Kaise H et al (2003) Ultrasound with tissue harmonic imaging in detection of axillary lymph node metastases in breast cancer patients. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

  66. Esen G, Gurses B, Ylmaz MH et al (2005) Gray scale and power doppler US in the preoperative evaluation of axillary metastases in breast cancer patients with no palpable lymph nodes. Eur Radiol 15(6):1215–1223

    Article  PubMed  Google Scholar 

  67. Rashmi S, Govardhan HB, Satyajt P et al (2014) Colour doppler – an evaluation tool for assessment of breast tumor size, axillary lymph node size and chemotherapeutic response. J Cancer Treat Res 2(2):9–15. doi:10.11648/j.jctr.20140202.11

    Article  Google Scholar 

  68. Han SY, Kim HH (2003) Parasternal sonography of the internal mammary lymphatics in breast cancer. 13th International congress on the ultrasonic examination of the breast. International Breast Ultrasound School. The 10th meeting of Japan Association of Breast and Thyroid Sonology

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology and Imaging Diagnosis, County Emergency Clinical Hospital, Craiova, Dolj, Romania

    Aristida Colan-Georges

Authors
  1. Aristida Colan-Georges
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Colan-Georges, A. (2016). Full Breast Ultrasonography of Malignant Lesions. In: Atlas of Full Breast Ultrasonography. Springer, Cham. https://doi.org/10.1007/978-3-319-31418-1_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-31418-1_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31417-4

  • Online ISBN: 978-3-319-31418-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation