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Physiological and Pathological Aspects of Full Breast Ultrasonography in Men and Children

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Abstract

In the male patient, US may help in distinguishing benign conditions of the mammary region, such as gynecomastia, from breast carcinoma. Many authors believe that the addition of US to mammography increases the diagnostic accuracy. However, US findings of malignancy in the male breast may be subtle, and the appearances of benign disease and malignant disease overlap. This chapter defines and illustrates the anatomy and the pathology of the breast in male and children from the point of view of full breast ultrasonography.

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References

  1. Georgescu AC, Enachescu V (2009) The diagnosis of gynecomastia by Doppler Ductal Ultrasonography. Etiopathogenic, endocrine and imaging correlations – partial data. Med Ultrason 11(3):33–40

    Google Scholar 

  2. Thomas DB, Jimenez LM, McTiernan A et al (1992) Breast cancer in men: risk factors with hormonal implications. Am J Epidemiol 135:734–748. PubMed Abstract

    CAS  PubMed  Google Scholar 

  3. Ramirez-Torres MA, Carrera A, Zambrana M (2000) High incidence of hyperestrogenemia and dyslipidemia in a group of infertile men. Ginecol Obstet Mex 68:224–229

    CAS  PubMed  Google Scholar 

  4. Fujimoto Y, Hatama M, Tezuka K, Otani H et al (2005) Ultrasonic screening of the thyroid in the patients with breast complaints. In: Research and development in breast ultrasound. Springer, Tokyo, pp 167–169

    Chapter  Google Scholar 

  5. Fujimoto Y, Kato Y, Maekawa H et al (1988) Ultrasonic screening of thyroid in the patients with breast complaints. J Ultrasound Med 7:39–S283

    Google Scholar 

  6. Benvenga S, Smedile G, Lo Giudice F et al (2000) Euthyroid hyperthyrotropinemia secondary to hyperestrogenemia in a male with congenital adrenal hyperplasia. Horm Metab Res 32(8):321–325, Page 50 of 50

    Article  CAS  PubMed  Google Scholar 

  7. De Rosa M, Zarrilli S, Di Sarno A et al (2003) Hyperprolactinemia in men. Clinical and biochemical features and response to treatment. Endocrine 20(1/2):75–82

    Article  PubMed  Google Scholar 

  8. Recchia AG, Vivacqua A, Gabriele S, Carpino A et al (2004) Xenoestrogens and the induction of proliferative effects in breast cancer cells via direct activation of oestrogen receptor alpha. Food Addit Contam 21(2):134–144

    Article  CAS  PubMed  Google Scholar 

  9. Vivacqua A, Recchia AG, Fasanella G, Gabriele S et al (2003) The food contaminants bisphenol A and 4-nonylphenol act as agonists for estrogen receptor alpha in MCF7 breast cancer cells. Endocrine 22(3):275–284

    Article  CAS  PubMed  Google Scholar 

  10. Evans GF, Anthony Y, Turnage RH et al (2001) The diagnostic accuracy of mammography in the evaluation of male breast disease. Am J Surg 181(2):96–100

    Article  CAS  PubMed  Google Scholar 

  11. Appelbaum AH, Evans GF, Levy KR et al (1999) Mammographic appearances of male breast disease. Radiographics 19(3):559–568

    Article  CAS  PubMed  Google Scholar 

  12. Cooper RA, Gunter BA, Ramamurthy L (1994) Mammography in men. Radiology 191(3):651–656

    Article  CAS  PubMed  Google Scholar 

  13. Berg WA (2006) Operator dependence of physician performed whole breast US: lesion detection and characterization. Radiology 214:355–365

    Article  Google Scholar 

  14. Hertl K, Marolt-Musik M, Kocijancic I et al (2009) Haematomas after percutaneous vacuum assisted breast biopsy. Ultraschall in Med 30:33–36. doi:10.1055/s-2007-963724

    Article  CAS  Google Scholar 

  15. Georgescu AC, Enachescu V, Bondari S (2010) The full breast Ultrasonography: an anatomical standardized imaging approach of the benign and malignant breast lesions. ECR, Vienna, EPOSTM. doi:10.1594/ecr2010/C-0434

  16. Georgescu AC, Enachescu V (2010) The diagnosis of gynecomastia by Doppler ductal ultrasonography: etiopathogenic, endocrine and imaging correlations. ECR, Vienna, EPOSTM. doi:10.1594/ecr2010/C-0420

  17. Renkes P, Gaucher P, Trechot P (1995) Spironolactone and hepatic toxicity. JAMA 273:376–377

    Article  CAS  PubMed  Google Scholar 

  18. Thompson D, Carter J (1993) Drug-induced gynecomastia. Pharmacotherapy 13:37–45

    CAS  PubMed  Google Scholar 

  19. Loube SD, Quirk RA (1975) Letter: breast cancer associated with administration of spironolactone. Lancet 1:1428–1429

    Article  CAS  PubMed  Google Scholar 

  20. Weiss RJ, Moysich BK, Swede H (2005) Epidemiology of male breast cancer. Cancer Epidemiol Biomarkers Prev 14(1):20–26

    PubMed  Google Scholar 

  21. Ruddy KJ, Winer EP (2013) Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship. Ann Oncol. doi:10.1093/annonc/mdt025

    PubMed  Google Scholar 

  22. Burga AM, Fadare O, Lininger RA et al (2006) Invasive carcinomas of the male breast: a morphologic study of the distribution of histologic subtypes and metastatic patterns in 778 cases. Virchows Arch 449(5):507–512

    Article  PubMed  PubMed Central  Google Scholar 

  23. Kornegoor R, Verschuur-Maes AH, Buerger H et al (2012) Molecular subtyping of male breast cancer by immunohistochemistry. Mod Pathol 25(3):398–404

    Article  CAS  PubMed  Google Scholar 

  24. Kujiraoka Y, Ueno E, Yohno E, Morishima I, Tsunoda-Shimizu H (2005) Incident angle of the plunging artery of breast tumors. In: Research and development in breast ultrasound. Springer, Tokyo, pp 72–75

    Chapter  Google Scholar 

  25. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA (1995) Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology 196:123–134

    Article  CAS  PubMed  Google Scholar 

  26. Olsson H, Bladstrom A, Alm P (2002) Male gynecomastia and risk for malignant tumours – a cohort study. BMC Cancer 2:26. doi:10.1186/1471-2407-2-26

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Georgescu AC, Andrei ME, Enachescu V, Bondari S (2013) New horizons in breast Doppler ductal echography: the positive and differential diagnosis of ductal ectasia, with etiopathological correlations. ECR, Viena, EPOSTM. doi:10.1594/ecr2013/C-0667

  28. Phillips BG, Pinkernell HB, Jing T-Y (1996) The association of hyperestrogenemia with coronary thrombosis in men. Arterioscler Thromb Vasc Biol 16:1383–1387

    Article  CAS  PubMed  Google Scholar 

  29. Luo JJ (2007) Hyperestrogenemia simulating kennedy disease. J Clin Neuromusc Dis 9(2):291–296

    Article  Google Scholar 

  30. Georgescu AC, Andrei ME, Manda A, Bondari S, Sendroiu I (2015) Contributions of imaging examinations in the diagnosis of the von Recklinghausen disease. ECR, Vienna, EPOSTM. doi:10.1594/ecr2015/C-1014

  31. Kaplowitz PB, Kemp S, Windle LM, Levitsky LL et al (2014) Precocious puberty. Medscape, 14 Oct. http://emedicine.medscape.com/article/924002-clinical

  32. Vade A, Lafita VS, Ward KA, Lim-Dunham JE, Bova D (2008) Role of breast sonography in imaging of adolescents with palpable solid breast masses. AJR Am J Roentgenol 191:659–663, © American Roentgen Ray Society

    Article  PubMed  Google Scholar 

  33. Bock K, Duda VF, Hadji P, Ramaswamy A, Schulz-Wendtland R, Klose K-J, Wagner U (2005) Pathologic breast conditions in childhood and adolescence evaluation by sonographic diagnosis. J Ultrasound Med 24:1347–1354, 0278–4297

    PubMed  Google Scholar 

  34. Weinstein SP, Conant EF, Orel SG, Zuckerman JA, Bellah R (2000) Spectrum of US findings in pediatric and adolescent patients with palpable breast masses. Radiographics 20:1613–1621, © RSNA, 2000

    Article  CAS  PubMed  Google Scholar 

  35. Kronemer KA, Rhee K, Siegel MJ et al (2001) Gray scale sonography of breast masses in adolescent girls. J Ultrasound Med 20(5):491–496, quiz 498. [Medline]

    CAS  PubMed  Google Scholar 

  36. Tot T (2007) The theory of the sick breast lobe and the possible consequences. Int J Surg Pathol 1:68–71

    Google Scholar 

  37. Chateil JF, Arboucalot F, Perel Y et al (1998) Breast metastasis in adolescent girls: US findings. Pediatr Radiol 28:832–835, CrossRef

    Article  CAS  PubMed  Google Scholar 

  38. Boothroyd A, Carty H (1994) Breast masses in childhood and adolescence: a presentation of 17 cases and a review of the literature. Pediatr Radiol 24:81–84, CrossRef

    Article  CAS  PubMed  Google Scholar 

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Colan-Georges, A. (2016). Physiological and Pathological Aspects of Full Breast Ultrasonography in Men and Children. In: Atlas of Full Breast Ultrasonography. Springer, Cham. https://doi.org/10.1007/978-3-319-31418-1_10

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  • DOI: https://doi.org/10.1007/978-3-319-31418-1_10

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31417-4

  • Online ISBN: 978-3-319-31418-1

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