Abstract
Diffusion Tensor Imaging (DTI), the Fractional Anisotropy (FA) is used to measure the integrity of the white matter (WM); it is considered as a biomarker for stroke recovery. This measure is highly sensitive to applied pre-processing steps; in particular, the presence of a lesion may result into severe misregistration. In this paper, it is proposed to quantitatively assess the impact of large stroke lesions onto the registration process. To reduce this impact, a new registration algorithm, that localizes the lesion via Bayesian estimation, is proposed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
See BRATS (http://braintumorsegmentation.org) and ISLES (http://www.isles-challenge.org): 2015’ medical imaging challenges on lesion segmentation.
References
Andersen, S.M., Rapcsak, S.Z., Beeson, P.M.: Cost function masking during normalization of brains with focal lesions: still a necessity? NeuroImage 53(1), 78–84 (2010)
Beg, M., Miller, M., Trouvé, A., Younes, L.: Computing large deformation metric mappings via geodesic flows of diffeomorphisms. Int. J. Comput. Vis. 61(2), 139–157 (2005)
Brett, M., Leff, A.P., Rorden, C., Ashburner, J.: Spatial normalization of brain images with focal lesions using cost function masking. Neuroimage 14(2), 486–500 (2001)
Ceccarelli, A., Jackson, J., Tauhid, S., Arora, A., Gorky, J., Dell’Oglio, E., Bakshi, A., Chitnis, T., Khoury, S., Weiner, H., Guttmann, C., Bakshi, R., Neema, M.: The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis. Am. J. Neuroradiol. 33(8), 1579–1585 (2012)
Jenkinson, M., Beckmann, C.F., Behrens, T.E., Woolrich, M.W., Smith, S.M.: FSL. NeuroImage 62(2), 782–790 (2012)
Lindenberg, R., Renga, V., Zhu, L.L., Betzler, F., Alsop, D., Schlaug, G.: Structural integrity of corticospinal motor fibers predicts motor impairment in chronic stroke. Neurology 74(4), 280–287 (2010)
Ripolles, P., Marco-Pallares, J., de Diego-Balaguer, R., Miro, J., Falip, M., Juncadella, M., Rubio, F., Rodriguez-Fornells, A.: Analysis of automated methods for spatial normalization of lesioned brains. Neuroimage 60(2), 1296–1306 (2012)
Scott, D.W.: Multivariate density estimation and visualization. Handbook of Computational Statistics, pp. 549–569. Springer, Heidelberg (2012)
Smith, S.M., Jenkinson, M., Johansen-Berg, H., Rueckert, D., Nichols, T.E., Mackay, C.E., Watkins, K.E., Ciccarelli, O., Cader, M.Z., Matthews, P.M., Behrens, T.E.: Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. NeuroImage 31(4), 1487–1505 (2006)
Song, J., Young, B.M., Nigogosyan, Z., Walton, L.M., Nair, V.A., Grogan, S.W., Tyler, M.E., Farrar-Edwards, D., Caldera, K.E., Sattin, J.A., Williams, J.C., Prabhakaran, V.: Characterizing relationships of DTI, fMRI, and motor recovery in stroke rehabilitation utilizing brain-computer interface technology. Frontiers in Neuroengineering 7, 31 (2014)
Vargas, P., Gaudron, M., Valabrgue, R., Bertasi, E., Humbert, F., Lehricy, S., Samson, Y., Rosso, C.: Assessment of corticospinal tract (CST) damage in acute stroke patients: comparison of tract-specific analysis versus segmentation of a CST template. J. Magn. Reson. Imaging 37(4), 836–845 (2013)
Acknowledgments
This study was partially supported by PHRC-HERMES, and by French ANR projects e-SwallHome (ANR-13-TECS-0011) and ERATRANIRMA (ANR-12-EMMA-0056).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this paper
Cite this paper
Renard, F., Urvoy, M., Jaillard, A. (2016). Bayesian Stroke Lesion Estimation for Automatic Registration of DTI Images. In: Crimi, A., Menze, B., Maier, O., Reyes, M., Handels, H. (eds) Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2015. Lecture Notes in Computer Science(), vol 9556. Springer, Cham. https://doi.org/10.1007/978-3-319-30858-6_9
Download citation
DOI: https://doi.org/10.1007/978-3-319-30858-6_9
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-30857-9
Online ISBN: 978-3-319-30858-6
eBook Packages: Computer ScienceComputer Science (R0)