Late Effects of Treatment and Palliative Care

  • Eric Chang
  • Robert Goldsby
  • Sabine Mueller
  • Anu BanerjeeEmail author
Part of the Pediatric Oncology book series (PEDIATRICO)


Identifying late effects of treatment and integrating palliative care when appropriate are increasingly recognized as important elements of childhood tumor management. Patients with CNS tumors are at a high risk for mortality, and survivors have high morbidity rates related to the late effects of treatment. While intensified therapy has improved average 5-year survival in patients with pediatric brain tumors to 73 % (Ostrom et al. 2014) from less than 60 % in 1975–1979 (Linabery and Ross 2008), it has also increased the long-term consequences. Survivors may develop a spectrum of late effects ranging from subtle memory loss and cosmetic anomalies to severe neurological disabilities and recurrent neoplasms. While seemingly quite different, both palliative and late-effects care focus on improving quality of life for patients and need to be integrated into the overall care plan.


Palliative Care Growth Hormone Deficiency Cranial Radiation Childhood Cancer Survivor Pediatric Brain Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer International Publishing 2017

Authors and Affiliations

  • Eric Chang
    • 1
  • Robert Goldsby
    • 2
  • Sabine Mueller
    • 3
  • Anu Banerjee
    • 2
    Email author
  1. 1.Department of Radiation OncologyUniversity of California Los AngelesLos AngelesUSA
  2. 2.Division of Hematology/Oncology, Departments of PediatricsUniversity of California San Francisco & UCSF Benioff Children’s HospitalSan FranciscoUSA
  3. 3.Departments of Neurology, Neurosurgery and PediatricsUniversity of California San Francisco & UCSF Benioff Children’s HospitalSan FranciscoUSA

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