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Applied Immunohistochemistry in the Evaluation of Skin Neoplasms pp 3–24Cite as

Immunohistology and Molecular Studies of Epithelial Tumors

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Abstract

Cutaneous epidermal neoplasms, including basal cell carcinoma and squamous cell carcinoma, often display characteristic microscopic findings that are readily recognized and do not constitute a diagnostic challenge for the dermatopathologist. There are occasional cases, however, that show atypical or ambiguous features and an unequivocal diagnosis is not easily rendered. In a small biopsy sample, these challenges can be amplified. Accurate diagnosis of cutaneous epidermal neoplasms is of paramount importance because therapeutic management and disease staging can be drastically different between the entities. Immunohistochemical studies, when appropriately applied, help in such distinction and play an essential role in their differentiation.

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Authors and Affiliations

  1. Dermatopathology Division, Miraca Life Sciences, Irving, TX, USA

    Heather Froehlich M.D.

  2. Miraca Life Sciences, Dermatopathology Division, 6655 MacArthur Boulevard, Dallas, Texas, 75039, USA

    Jose A. Plaza M.D.

Authors
  1. Heather Froehlich M.D.
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  2. Jose A. Plaza M.D.
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Correspondence to Heather Froehlich M.D. .

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Editors and Affiliations

  1. Miraca Life Sciences, Dermatopathology Division, Dallas, Texas, USA

    Jose A. Plaza

  2. Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

    Victor G. Prieto

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Froehlich, H., Plaza, J.A. (2016). Immunohistology and Molecular Studies of Epithelial Tumors. In: Plaza, J., Prieto, V. (eds) Applied Immunohistochemistry in the Evaluation of Skin Neoplasms. Springer, Cham. https://doi.org/10.1007/978-3-319-30590-5_1

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  • DOI: https://doi.org/10.1007/978-3-319-30590-5_1

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