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Allogeneic Hematopoietic Cell Transplant in Sickle Cell Disease

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Abstract

Sickle cell disease (SCD) affects approximately 100,000 people in the United States and over 25 million people worldwide. The hemoglobin S mutation in the β-globin chain leads to hemoglobin polymerization under deoxygenated conditions and results in a myriad of acute and chronic complications and early death.

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Authors and Affiliations

  1. Departments of Medicine, Hematology and Oncology, University of Illinois, Chicago, IL, USA

    Santosh L. Saraf MD

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  1. Santosh L. Saraf MD
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Correspondence to Santosh L. Saraf MD .

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Editors and Affiliations

  1. Cancer Treatment Centers of America, Department of Hematology and Bone Marrow Transplantion, Zion, Illinois, USA

    Syed A. Abutalib

  2. Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, Massachusetts, USA

    Jean M. Connors

  3. Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

    Margaret V. Ragni

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Saraf, S.L. (2016). Allogeneic Hematopoietic Cell Transplant in Sickle Cell Disease. In: Abutalib, S., Connors, J., Ragni, M. (eds) Nonmalignant Hematology. Springer, Cham. https://doi.org/10.1007/978-3-319-30352-9_9

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  • DOI: https://doi.org/10.1007/978-3-319-30352-9_9

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