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Centralized HMES with Environment Adaptation for Production of Radiopharmaceuticals

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Service Orientation in Holonic and Multi-Agent Manufacturing

Part of the book series: Studies in Computational Intelligence ((SCI,volume 640))

Abstract

The paper presents an intelligent hybrid control solution for the production of radiopharmaceuticals that irradiates radioactive isotopes of neutron-defficient radionuclides type by in cyclotrons. To achieve requirements such as: highest number of orders accepted daily, shortest production time and safe operating conditions, a hybrid control system based on a dual architecture: centralized HMES with ILOG planning and decentralized parameter monitoring and control via SCADA is developed. Experimental results are reported.

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References

  1. Iverson, Ch. et al. (eds.): 15.9.2 radiopharmaceuticals. In: AMA Manual of Style (10th edn). Oxford University Press, Oxford, Oxfordshire (2007). ISBN 978-0-19-517633-9

    Google Scholar 

  2. Schwochau, K.: Technetium. Wiley-VCH (2000). ISBN 3-527-29496-1

    Google Scholar 

  3. Ell, P., Gambhir, S.: Nuclear Medicine in Clinical Diagnosis and Treatment. Churchill Livingstone (2004). ISBN 978-0-443-07312-0

    Google Scholar 

  4. http://www.sciencedaily.com/releases/2010/07/100708111326.htm

  5. http://www.ansto.gov.au/_data/assets/pdf_file/0019/32941/Nuclear_Medicine_Brochure_May08.pdf

  6. Mas, J.C.: A patient’s guide to nuclear medicine procedures: English–Spanish. Soc. Nucl. Med (2008). ISBN 978-0-9726478-9-2

    Google Scholar 

  7. Medema, J., Luurtsema, G., Keizer, H., Tjilkema, S., Elsinga, P.H., Franssen, E.J.F., Paans, A.M.J., Vaalburg, W.: Fully automated and unattended [18F] fluoride and [18F] FDG production using PLC controlled systems. In: Proceedings of the 31st European Cyclotron Progress Meeting, Zurich (1997)

    Google Scholar 

  8. Kusiak, A.: Intelligent Manufacturing Systems. Prentice Hall, Englewood Cliffs (1990). ISBN 0-13-468364-1

    MATH  Google Scholar 

  9. Tsai, W.T.: Service-oriented system engineering: a new paradigm. In: Proceedings of the 2005 IEEE International Workshop on Service-Oriented System Engineering (SOSE’05). IEEE Computer Society (2005). 0-7695-2438-9/05

    Google Scholar 

  10. De Deugd, S., Carroll, R., Kelly, K.E., Millett, B., Ricker, J.: SODA: service-oriented device architecture. IEEE Pervasive Comput. 5(3), 94–96 (2006)

    Article  Google Scholar 

  11. McFarlane, D., Giannikas, V., Wong, C.Y., Harrison, M.: Product intelligence in industrial control: theory and practice. Ann. Rev. Control 37, 69–88 (2013)

    Article  Google Scholar 

  12. Van Brussel, H., Wyns, J., Valckenaers, P., Bongaerts, L., Peeters, P.: Reference architecture for holonic manufacturing systems: PROSA. Comput. Ind. (Special Issue on Intelligent Manufacturing Systems) 37(3), 255–276 (1998)

    Google Scholar 

  13. Leitao, P., Restivo, F.: ADACOR: a holonic architecture for agile and adaptive manufacturing control. Comput. Ind. 57(2), 121–130 (2006)

    Article  Google Scholar 

  14. Raileanu, S., Anton, F., Iatan, A., Borangiu, Th., Anton, S., Morariu, O.: Resource scheduling based on energy consumption for sustainable manufacturing. J. Intell. Manuf. Springer (2015). Print ISSN: 0956-5515, On line ISSN: 1572-8145, doi:10.1007/s10845-015-1142-5

    Google Scholar 

  15. Novas, J.M., Bahtiar, R., Van Belle, J., Valckenaers, P.: An approach for the integration of a scheduling system and a multiagent manufacturing execution system. towards a collaborative framework. In: Proceedings of the 14th IFAC Symposium INCOM’12, Bucharest, pp. 728–733, IFAC Papers OnLine (2012)

    Google Scholar 

  16. www.constraintsolving.com/solvers. Consulted in Oct 2015

  17. ILOG: (2009). www-01.ibm.com/software/websphere/ilog/. Consulted in Oct 2015

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Acknowledgment

This work is supported by the Sectorial Operational Programme Human Resources Development (SOP HRD), financed from the European Social Fund and the Romanian Government under the contract number POSDRU/159/1.5/S/137390/.

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Correspondence to Silviu Răileanu .

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Răileanu, S., Borangiu, T., Silişteanu, A. (2016). Centralized HMES with Environment Adaptation for Production of Radiopharmaceuticals. In: Borangiu, T., Trentesaux, D., Thomas, A., McFarlane, D. (eds) Service Orientation in Holonic and Multi-Agent Manufacturing. Studies in Computational Intelligence, vol 640. Springer, Cham. https://doi.org/10.1007/978-3-319-30337-6_1

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  • DOI: https://doi.org/10.1007/978-3-319-30337-6_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-30335-2

  • Online ISBN: 978-3-319-30337-6

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