Abstract
In the previous Chap. 1 showed advantages and limitations of the 2D in vitro model. By taking into account the limitations of such a model, it is an evidence that there is a tremendous need to develop culture systems that more closely mimic the complexity of nervous tissue. It is required to scale up from 2D neuronal network model to 3D neuronal network model.
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Abeles M (1991) Corticonics: neural circuits of the cerebral cortex. Cambridge University Press, Cambridge
Balgude AP, Yu X et al (2001) Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. Biomaterials 22(10):1077–1084
Baranes D, Cove J et al (2007) Interconnected network of ganglion-like neural cell spheres formed on hydrozoan skeleton. Tissue Eng 13(3):473–482
Behravesh E, Emami K et al (2005) Comparison of genotoxic damage in monolayer cell cultures and three-dimensional tissue-like cell assemblies. Adv Space Res 35(2):260–267
Bellamkonda R, Ranieri JP et al (1995) Hydrogel-based three-dimensional matrix for neural cells. J Biomed Mater Res 29(5):663–671
Berthod F, Hayek D et al (1993) Collagen synthesis by fibroblasts cultured within a collagen sponge. Biomaterials 14(10):749–754
Birgersdotter A, Sandberg R et al (2005) Gene expression perturbation in vitro–a growing case for three-dimensional (3D) culture systems. Semin Cancer Biol 15(5):405–412
Blackshaw SE, Arkison S et al (1997) Promotion of regeneration and axon growth following injury in an invertebrate nervous system by the use of three-dimensional collagen gels. Proc Biol Sci 264(1382):657–661
Castillon N, Hinnrasky J et al (2002) Polarized expression of cystic fibrosis transmembrane conductance regulator and associated epithelial proteins during the regeneration of human airway surface epithelium in three-dimensional culture. Lab Invest 82(8):989–998
Choi HK, Won L et al (1993) Dopaminergic neurons grown in three-dimensional reaggregate culture for periods of up to one year. J Neurosci Methods 46(3):233–244
Chun TH, Hotary KB et al (2006) A pericellular collagenase directs the 3-dimensional development of white adipose tissue. Cell 125(3):577–591
Cukierman E, Pankov R et al (2001) Taking cell-matrix adhesions to the third dimension. Science 294(5547):1708–1712
Cukierman E, Pankov R et al (2002) Cell interactions with three-dimensional matrices. Curr Opin Cell Biol 14(5):633–639
Cullen DK, Wolf JA et al (2011) Neural tissue engineering and biohybridized microsystems for neurobiological investigation in vitro (Part 1). Crit Rev Biomed Eng 39(3):201–240
Desai A, Kisaalita WS et al (2006) Human neuroblastoma (SH-SY5Y) cell culture and differentiation in 3-D collagen hydrogels for cell-based biosensing. Biosens Bioelectron 21(8):1483–1492
Fawcett JW, Barker RA et al (1995) Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon. Exp Brain Res 106(2):275–282
Fawcett JW, Housden E et al (1989) The growth of axons in three-dimensional astrocyte cultures. Dev Biol 135(2):449–458
Friedl P, Zanker KS et al (1998) Cell migration strategies in 3-D extracellular matrix: differences in morphology, cell matrix interactions, and integrin function. Microsc Res Tech 43(5):369–378
Granet C, Laroche N et al (1998) Rotating-wall vessels, promising bioreactors for osteoblastic cell culture: comparison with other 3D conditions. Med Biol Eng Comput 36(4):513–519
Grinnell F (2000) Fibroblast-collagen-matrix contraction: growth-factor signalling and mechanical loading. Trends Cell Biol 10(9):362–365
Grinnell F (2003) Fibroblast biology in three-dimensional collagen matrices. Trends Cell Biol 13(5):264–269
Hindie M, Vayssade M et al (2006) Interactions of B16F10 melanoma cells aggregated on a cellulose substrate. J Cell Biochem 99(1):96–104
Hofmann RM (1993) To do tissue culture in two or three dimensions? That is the question. Stem Cells 11(2):105–111
Horie H, Akahori Y (1994) Three-dimensional cell aggregation enhances growth-promoting activity of NGF in adult DRG. NeuroReport 6(1):37–40
Huang YC, Huang YY (2006) Biomaterials and strategies for nerve regeneration. Artif Organs 30(7):514–522
Kiryushko D, Berezin V et al (2004) Regulators of neurite outgrowth: role of cell adhesion molecules. Ann N Y Acad Sci 1014:140–154
LaPlaca MC, Cullen DK et al (2005) High rate shear strain of three-dimensional neural cell cultures: a new in vitro traumatic brain injury model. J Biomech 38(5):1093–1105
Lee J, Cuddihy MJ et al (2008) Three-dimensional cell culture matrices: state of the art. Tissue engineering Part B, Reviews 14(1):61–86
Letourneau P (1975a) Possible roles of cell to substratum adhesion in neuronal morphogenesis. Dev Biol 44:77–91
Letourneau PC (1975b) Cell-to-substratum adhesion and guidance of axonal elongation. Dev Biol 44(1):92–101
Liu H, Lin J et al (2006) Effect of 3D scaffold and dynamic culture condition on the global gene expression profile of mouse embryonic stem cells. Biomaterials 27(36):5978–5989
Loers G, Schachner M (2007) Recognition molecules and neural repair. J Neurochem 101(4):865–882
Ma W, Fitzgerald W et al (2004) CNS stem and progenitor cell differentiation into functional neuronal circuits in three-dimensional collagen gels. Exp Neurol 190(2):276–288
Mao C, Kisaalita WS (2004) Characterization of 3-D collagen hydrogels for functional cell-based biosensing. Biosens Bioelectron 19(9):1075–1088
Masi L, Franchi A et al (1992) Adhesion, growth, and matrix production by osteoblasts on collagen substrata. Calcif Tissue Int 51(3):202–212
Miller BE, Miller FR et al (1985) Factors affecting growth and drug sensitivity of mouse mammary tumor lines in collagen gel cultures. Cancer Res 45(9):4200–4205
Pardo B, Honegger P (2000) Differentiation of rat striatal embryonic stem cells in vitro: monolayer culture vs. three-dimensional coculture with differentiated brain cells. J Neurosci Res 59(4):504–512
Pautot S, Wyart C et al (2008) Colloid-guided assembly of oriented 3D neuronal networks. Nat Methods 5(8):735–740
Pedersen JA, Swartz MA (2005) Mechanobiology in the third dimension. Ann Biomed Eng 33(11):1469–1490
Pusey PN, Vanmegen W (1986) Phase-behavior of concentrated suspensions of nearly hard colloidal spheres. Nature 320:340–342
Schindler M, Nur EKA et al (2006) Living in three dimensions: 3D nanostructured environments for cell culture and regenerative medicine. Cell Biochem Biophys 45(2):215–227
Schmeichel KL, Bissell MJ (2003) Modeling tissue-specific signaling and organ function in three dimensions. J Cell Sci 116(Pt 12):2377–2388
Schmidt CE, Leach JB (2003) Neural tissue engineering: strategies for repair and regeneration. Annu Rev Biomed Eng 5:293–347
Schuz A, Palm G (1989) Density of neurons and synapses in the cerebral cortex of the mouse. J Comp Neurol 286(4):442–455
Shany B, Vago R et al (2005) Growth of primary hippocampal neuronal tissue on an aragonite crystalline biomatrix. Tissue Eng 11(3–4):585–596
Smalley KS, Lioni M et al (2006) Life isn’t flat: taking cancer biology to the next dimension. In Vitro Cell Dev Biol Anim 42(8–9):242–247
van Blaaderen A, Ruel R et al (1997) Template-directed colloidal crystallization. Nature 385:321–324
Venstrom KA, Reichardt LF (1993) Extracellular matrix. 2: Role of extracellular matrix molecules and their receptors in the nervous system. FASEB J 7(11):996–1003
Wang F, Weaver VM et al (1998) Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proc Natl Acad Sci U S A 95(25):14821–14826
Willerth SM, Arendas KJ et al (2006) Optimization of fibrin scaffolds for differentiation of murine embryonic stem cells into neural lineage cells. Biomaterials 27(36):5990–6003
Xu T, Gregory CA et al (2006) Viability and electrophysiology of neural cell structures generated by the inkjet printing method. Biomaterials 27(19):3580–3588
Yamada KM, Pankov R et al (2003) Dimensions and dynamics in integrin function. Braz J Med Biol Res 36(8):959–966
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Frega, M. (2016). 3D Neuronal Networks: State of the Art. In: Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-30237-9_4
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